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Neel H. Shah
Neel H. Shah
Assistant Professor, Columbia University
Verifierad e-postadress på columbia.edu - Startsida
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Inteins: nature's gift to protein chemists
NH Shah, TW Muir
Chemical Science 5 (2), 446-461, 2014
4192014
Oligo (N-aryl glycines): a new twist on structured peptoids
NH Shah, GL Butterfoss, K Nguyen, B Yoo, R Bonneau, DL Rabenstein, ...
Journal of the American Chemical Society 130 (49), 16622-16632, 2008
2122008
Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering
NH Shah, GP Dann, M Vila-Perelló, Z Liu, TW Muir
Journal of the American Chemical Society 134 (28), 11338-11341, 2012
1672012
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
WL Lo, NH Shah, N Ahsan, V Horkova, O Stepanek, AR Salomon, ...
Nature immunology 19 (7), 733-741, 2018
1482018
Design of a Split Intein with Exceptional Protein Splicing Activity
AJ Stevens, ZZ Brown, NH Shah, G Sekar, D Cowburn, TW Muir
Journal of the American Chemical Society 138 (7), 2162-2165, 2016
1482016
ZAP-70 in signaling, biology, and disease
BB Au-Yeung, NH Shah, L Shen, A Weiss
Annual review of immunology 36, 127-156, 2018
1362018
A promiscuous split intein with expanded protein engineering applications
AJ Stevens, G Sekar, NH Shah, AZ Mostafavi, D Cowburn, TW Muir
Proceedings of the National Academy of Sciences 114 (32), 8538-8543, 2017
1192017
Deconstruction of the Ras switching cycle through saturation mutagenesis
P Bandaru, NH Shah, M Bhattacharyya, JP Barton, Y Kondo, JC Cofsky, ...
eLife 6, e27810, 2017
1142017
Streamlined expressed protein ligation using split inteins
M Vila-Perelló, Z Liu, NH Shah, JA Willis, J Idoyaga, TW Muir
Journal of the American Chemical Society 135 (1), 286-292, 2013
1082013
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor
NH Shah, Q Wang, Q Yan, D Karandur, TA Kadlecek, IR Fallahee, ...
Elife 5, e20105, 2016
922016
Naturally split inteins assemble through a “capture and collapse” mechanism
NH Shah, E Eryilmaz, D Cowburn, TW Muir
Journal of the American Chemical Society 135 (49), 18673-18681, 2013
892013
Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split intein
NH Shah, M Vila-Perelló, TW Muir
Angewandte Chemie (International ed. in English) 50 (29), 6511, 2011
862011
Structural and dynamical features of inteins and implications on protein splicing
E Eryilmaz, NH Shah, TW Muir, D Cowburn
Journal of Biological Chemistry 289 (21), 14506-14511, 2014
842014
Extein residues play an intimate role in the rate-limiting step of protein trans-splicing
NH Shah, E Eryilmaz, D Cowburn, TW Muir
Journal of the American Chemical Society 135 (15), 5839-5847, 2013
842013
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination
WL Lo, NH Shah, SA Rubin, W Zhang, V Horkova, IR Fallahee, ...
Nature immunology 20 (11), 1481-1493, 2019
752019
Peptoid atropisomers
B Paul, GL Butterfoss, MG Boswell, PD Renfrew, FG Yeung, NH Shah, ...
Journal of the American Chemical Society 133 (28), 10910-10919, 2011
672011
The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases
NH Shah, JF Amacher, LM Nocka, J Kuriyan
Critical Reviews in Biochemistry and Molecular Biology, 2018
652018
SPLIT INTEINS, CONJUGATES AND USES THEREOF
TW Muir, M Vila-perello, Z Liu, NH Shah
US Patent 20,150,344,549, 2015
632015
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning
HT Rube, C Rastogi, S Feng, JF Kribelbauer, A Li, B Becerra, LAN Melo, ...
Nature Biotechnology 40 (10), 1520-1527, 2022
592022
Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen
NH Shah, M Löbel, A Weiss, J Kuriyan
eLife 7, e35190, 2018
582018
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Artiklar 1–20