| The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis SPS Rao, S Alonso, L Rand, T Dick, K Pethe Proceedings of the National Academy of Sciences 105 (33), 11945-11950, 2008 | 453 | 2008 |
| Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ... Nature medicine 19 (9), 1157-1160, 2013 | 392 | 2013 |
| Use of proteomics to identify novel virulence determinants that are required for Edwardsiella tarda pathogenesis PS Srinivasa Rao, Y Yamada, YP Tan, KY Leung Molecular microbiology 53 (2), 573-586, 2004 | 236 | 2004 |
| Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness S Khare, AS Nagle, A Biggart, YH Lai, F Liang, LC Davis, SW Barnes, ... Nature 537 (7619), 229-233, 2016 | 234 | 2016 |
| A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy K Pethe, PC Sequeira, S Agarwalla, K Rhee, K Kuhen, WY Phong, V Patel, ... Nature communications 1 (1), 1-8, 2010 | 221 | 2010 |
| Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability M Gengenbacher, SPS Rao, K Pethe, T Dick Microbiology 156 (1), 81-87, 2010 | 221 | 2010 |
| Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis S Hasan, S Daugelat, PSS Rao, M Schreiber PLoS Comput Biol 2 (6), e61, 2006 | 169 | 2006 |
| Opsonized virulent Edwardsiella tarda strains are able to adhere to and survive and replicate within fish phagocytes but fail to stimulate reactive oxygen intermediates PSS Rao, TM Lim, KY Leung Infection and immunity 69 (9), 5689-5697, 2001 | 163 | 2001 |
| A type III secretion system is required for Aeromonas hydrophila AH-1 pathogenesis HB Yu, PSS Rao, HC Lee, S Vilches, S Merino, JM Tomas, KY Leung Infection and immunity 72 (3), 1248-1256, 2004 | 144 | 2004 |
| The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease EK Schmitt, M Riwanto, V Sambandamurthy, S Roggo, C Miault, ... Angewandte Chemie 123 (26), 6011-6013, 2011 | 132 | 2011 |
| Functional genomics approach to the identification of virulence genes involved in Edwardsiella tarda pathogenesis PSS Rao, TM Lim, KY Leung Infection and immunity 71 (3), 1343-1351, 2003 | 126 | 2003 |
| Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin KL Low, PSS Rao, G Shui, AK Bendt, K Pethe, T Dick, MR Wenk Journal of bacteriology 191 (16), 5037-5043, 2009 | 122 | 2009 |
| The effectiveness of a commercial microbial product in poorly prepared tiger shrimp, Penaeus monodon (Fabricius), ponds M Shariff, FM Yusoff, TN Devaraja, PSS Rao Aquaculture Research 32 (3), 181-187, 2001 | 118 | 2001 |
| Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis SPS Rao, SB Lakshminarayana, RR Kondreddi, M Herve, LR Camacho, ... Science translational medicine 5 (214), 214ra168-214ra168, 2013 | 115 | 2013 |
| A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis PA Mak, SPS Rao, M Ping Tan, X Lin, J Chyba, J Tay, SH Ng, BH Tan, ... ACS chemical biology 7 (7), 1190-1197, 2012 | 114 | 2012 |
| A major catalase (KatB) that is required for resistance to H2O2 and phagocyte-mediated killing in Edwardsiella tarda PSS Rao, Y Yamada, KY Leung Microbiology 149 (9), 2635-2644, 2003 | 112 | 2003 |
| Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents SB Lakshminarayana, TB Huat, PC Ho, UH Manjunatha, V Dartois, T Dick, ... Journal of Antimicrobial Chemotherapy 70 (3), 857-867, 2015 | 92 | 2015 |
| Edwardsiella tarda mutants defective in siderophore production, motility, serum resistance and catalase activity JA Mathew, YP Tan, PSS Rao, TM Lim, KY Leung Microbiology 147 (2), 449-457, 2001 | 84 | 2001 |
| Design, synthesis and biological evaluation of indole-2-carboxamides, a promising class of anti-tuberculosis agents PWS Ravinder Reddy Kondreddi, Jan Jiricek, Srinivasa P Journal of Medicinal Chemistry, 2013 | 77 | 2013 |
| Direct inhibitors of InhA are active against Mycobacterium tuberculosis UH Manjunatha, SPS Rao, RR Kondreddi, CG Noble, LR Camacho, ... Science translational medicine 7 (269), 269ra3-269ra3, 2015 | 75 | 2015 |
