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Jenson Verghese
Jenson Verghese
Principal Scientist, Process Chemistry, Pfizer Inc.
Verified email at pfizer.com
Title
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Cited by
Year
First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa
J Verghese, A Liang, PPS Sidhu, M Hindle, Q Zhou, UR Desai
Bioorganic & medicinal chemistry letters 19 (15), 4126-4129, 2009
552009
High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine
RNDBFG E Yu, H. P. R. Mangunuru, N. S. Telang, C. J. Kong, J Verghese, S. E ...
Beilstein Journal of Organic Chemistry 14, 583 - 592, 2018
442018
Increasing global access to the high-volume HIV drug nevirapine through process intensification
J Verghese, C Kong, D Rivalti, E Yu, R Krack, J Alcázar, JB Manley, ...
Green Chemistry 19 (13), 2986-2991, 2017
392017
Flavone-based analogues inspired by the natural product simocyclinone D8 as DNA gyrase inhibitors
J Verghese, T Nguyen, LM Oppegard, LM Seivert, H Hiasa, KC Ellis
Bioorganic & medicinal chemistry letters 23 (21), 5874-5877, 2013
292013
Electrochemical oxidation of alcohols using nickel oxide hydroxide as heterogeneous electrocatalyst in batch and continuous flow
W Jud, CA Salazar, J Imbrogno, J Verghese, SM Guinness, JN Desrosiers, ...
Organic Process Research & Development 26 (5), 1486-1495, 2022
202022
Phenylalanine-based inactivator of AKT kinase: design, synthesis, and biological evaluation
T Nguyen, RA Coover, J Verghese, RG Moran, KC Ellis
ACS medicinal chemistry letters 5 (5), 462-467, 2014
192014
CoMFA study on thiazolidine-2, 4-diones for their antihyperglycemic activity
BR Prashantha Kumar, BJ Desai, J Vergheese, TK Praveen, B Suresh, ...
Letters in Drug Design & Discovery 5 (2), 79-87, 2008
122008
Rigid and flexible docking studies on PPAR-γ agonists: key interactions for a better antihyperglycemic activity and in silico pharmacodynamic activity versus experimental in …
BR Prashantha Kumar, S Sopna, J Verghese, B Desai, MJ Nanjan
Medicinal Chemistry Research 21, 624-633, 2012
62012
Metal‐Free Electrochemical Reduction of Disulfides in an Undivided Cell under Mass Transfer Control
BK Malviya, EC Hansen, CJ Kong, J Imbrogno, J Verghese, SM Guinness, ...
Chemistry–A European Journal 29 (66), e202302664, 2023
12023
Scalable Quasi-Divided Cell Operation Using Spinning Cylinder Electrode Technology: Multigram Electrochemical Synthesis of an Axitinib Intermediate
BK Malviya, EC Hansen, CJ Kong, J Imbrogno, J Verghese, SM Guinness, ...
Organic Process Research & Development 28 (3), 790-797, 2024
2024
Overriding Innate Decomposition Temperatures of an Avibactam Prodrug Precursor Using Data Science-Guided Synthesis
J Werth, M Butler, J Verghese, NM Do, L Samp, R Duzguner, ...
Organic Process Research & Development, 2023
2023
Utilizing Ni-Catalyzed Cross-Coupling as a Reversed Strategy for Homogeneous Deprotection of Benzyl Ethers in Batch and Flow
CE Griesbach, JN Desrosiers, L Sharninghausen, T Makowski, ...
Organic Process Research & Development, 2023
2023
J.-N. DESROSIERS, CO KAPPE, D. CANTILLO*(UNIVERSITY OF GRAZ AND RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH, GRAZ, AUSTRIA)
W JUD, CA SALAZAR, J IMBROGNO, J VERGHESE, SM GUINNESS
Org. Process Res. Dev 26, 1486-1495, 2022
2022
Key improvements towards the preparation of antiretroviral drug tenofovir
S Korwar, E Yu, AR Ehle, J Verghese, D Rivalti, F Gupton
ACS National Meeting & Exposition, San Francisco, CA, United States, ORGN-761, 2017
2017
Development of cost-​effective, streamlined access towards Nevirapine for batch and continuous manufacturing platforms
J Verghese, C Kong, S Ahmad, K Belecki, F Gupton
ACS National Meeting & Exposition, Philadelphia, PA, United States, ORGN-107, 2016
2016
Key process developments towards the preparation of tenofovir
A Ehle, J Verghese, D Rivalti, F Gupton
ACS National Meeting & Exposition, Philadelphia, PA, United States, ORGN-700, 2016
2016
Lowcost, high yield synthesis of nevirapine
TM Saeed Ahmad Frank Gupton Jenson VERGHESE
WO Patent WO2016118586A1, 2016
2016
Investigations of novel mechanisms of action for anti-bacterial and anti-cancer agent development
J Verghese
Virginia Commonwealth University, 2014
2014
Synthesis and Biochemical Studies on Sulfated Monomers of Low Molecular Weight Lignins
J Verghese
2009
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