First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa J Verghese, A Liang, PPS Sidhu, M Hindle, Q Zhou, UR Desai Bioorganic & medicinal chemistry letters 19 (15), 4126-4129, 2009 | 55 | 2009 |
High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine RNDBFG E Yu, H. P. R. Mangunuru, N. S. Telang, C. J. Kong, J Verghese, S. E ... Beilstein Journal of Organic Chemistry 14, 583 - 592, 2018 | 44 | 2018 |
Increasing global access to the high-volume HIV drug nevirapine through process intensification J Verghese, C Kong, D Rivalti, E Yu, R Krack, J Alcázar, JB Manley, ... Green Chemistry 19 (13), 2986-2991, 2017 | 39 | 2017 |
Flavone-based analogues inspired by the natural product simocyclinone D8 as DNA gyrase inhibitors J Verghese, T Nguyen, LM Oppegard, LM Seivert, H Hiasa, KC Ellis Bioorganic & medicinal chemistry letters 23 (21), 5874-5877, 2013 | 29 | 2013 |
Electrochemical oxidation of alcohols using nickel oxide hydroxide as heterogeneous electrocatalyst in batch and continuous flow W Jud, CA Salazar, J Imbrogno, J Verghese, SM Guinness, JN Desrosiers, ... Organic Process Research & Development 26 (5), 1486-1495, 2022 | 20 | 2022 |
Phenylalanine-based inactivator of AKT kinase: design, synthesis, and biological evaluation T Nguyen, RA Coover, J Verghese, RG Moran, KC Ellis ACS medicinal chemistry letters 5 (5), 462-467, 2014 | 19 | 2014 |
CoMFA study on thiazolidine-2, 4-diones for their antihyperglycemic activity BR Prashantha Kumar, BJ Desai, J Vergheese, TK Praveen, B Suresh, ... Letters in Drug Design & Discovery 5 (2), 79-87, 2008 | 12 | 2008 |
Rigid and flexible docking studies on PPAR-γ agonists: key interactions for a better antihyperglycemic activity and in silico pharmacodynamic activity versus experimental in … BR Prashantha Kumar, S Sopna, J Verghese, B Desai, MJ Nanjan Medicinal Chemistry Research 21, 624-633, 2012 | 6 | 2012 |
Metal‐Free Electrochemical Reduction of Disulfides in an Undivided Cell under Mass Transfer Control BK Malviya, EC Hansen, CJ Kong, J Imbrogno, J Verghese, SM Guinness, ... Chemistry–A European Journal 29 (66), e202302664, 2023 | 1 | 2023 |
Scalable Quasi-Divided Cell Operation Using Spinning Cylinder Electrode Technology: Multigram Electrochemical Synthesis of an Axitinib Intermediate BK Malviya, EC Hansen, CJ Kong, J Imbrogno, J Verghese, SM Guinness, ... Organic Process Research & Development 28 (3), 790-797, 2024 | | 2024 |
Overriding Innate Decomposition Temperatures of an Avibactam Prodrug Precursor Using Data Science-Guided Synthesis J Werth, M Butler, J Verghese, NM Do, L Samp, R Duzguner, ... Organic Process Research & Development, 2023 | | 2023 |
Utilizing Ni-Catalyzed Cross-Coupling as a Reversed Strategy for Homogeneous Deprotection of Benzyl Ethers in Batch and Flow CE Griesbach, JN Desrosiers, L Sharninghausen, T Makowski, ... Organic Process Research & Development, 2023 | | 2023 |
J.-N. DESROSIERS, CO KAPPE, D. CANTILLO*(UNIVERSITY OF GRAZ AND RESEARCH CENTER PHARMACEUTICAL ENGINEERING GMBH, GRAZ, AUSTRIA) W JUD, CA SALAZAR, J IMBROGNO, J VERGHESE, SM GUINNESS Org. Process Res. Dev 26, 1486-1495, 2022 | | 2022 |
Key improvements towards the preparation of antiretroviral drug tenofovir S Korwar, E Yu, AR Ehle, J Verghese, D Rivalti, F Gupton ACS National Meeting & Exposition, San Francisco, CA, United States, ORGN-761, 2017 | | 2017 |
Development of cost-effective, streamlined access towards Nevirapine for batch and continuous manufacturing platforms J Verghese, C Kong, S Ahmad, K Belecki, F Gupton ACS National Meeting & Exposition, Philadelphia, PA, United States, ORGN-107, 2016 | | 2016 |
Key process developments towards the preparation of tenofovir A Ehle, J Verghese, D Rivalti, F Gupton ACS National Meeting & Exposition, Philadelphia, PA, United States, ORGN-700, 2016 | | 2016 |
Lowcost, high yield synthesis of nevirapine TM Saeed Ahmad Frank Gupton Jenson VERGHESE WO Patent WO2016118586A1, 2016 | | 2016 |
Investigations of novel mechanisms of action for anti-bacterial and anti-cancer agent development J Verghese Virginia Commonwealth University, 2014 | | 2014 |
Synthesis and Biochemical Studies on Sulfated Monomers of Low Molecular Weight Lignins J Verghese | | 2009 |