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Aditya Sudheer Vaidya
Aditya Sudheer Vaidya
Other namesAditya S.Vaidya
Senior Scientist, Chemical Biology Innovation
Verified email at milliporesigma.com
Title
Cited by
Cited by
Year
Dynamic control of plant water use using designed ABA receptor agonists
AS Vaidya, JDM Helander, FC Peterson, D Elzinga, W Dejonghe, ...
Science 366 (6464), eaaw8848, 2019
1362019
A rationally designed agonist defines subfamily IIIA abscisic acid receptors as critical targets for manipulating transpiration
AS Vaidya, FC Peterson, D Yarmolinsky, E Merilo, I Verstraeten, SY Park, ...
ACS Chemical Biology 12 (11), 2842-2848, 2017
692017
Chemical manipulation of plant water use
JDM Helander, AS Vaidya, SR Cutler
Bioorganic & Medicinal Chemistry 24 (3), 493-500, 2016
672016
A chimeric SERM–histone deacetylase inhibitor approach to breast cancer therapy
HK Patel, MI Siklos, H Abdelkarim, EL Mendonca, A Vaidya, PA Petukhov, ...
ChemMedChem 9 (3), 602-613, 2014
272014
Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’binding pose
AS Vaidya, R Neelarapu, A Madriaga, H Bai, E Mendonca, H Abdelkarim, ...
Bioorganic & medicinal chemistry letters 22 (21), 6621-6627, 2012
262012
Defining and exploiting hypersensitivity hotspots to facilitate abscisic acid agonist optimization
D Elzinga, E Sternburg, D Sabbadin, M Bartsch, SY Park, A Vaidya, ...
ACS chemical biology 14 (3), 332-336, 2019
252019
Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo
AS Vaidya, FC Peterson, J Eckhardt, Z Xing, SY Park, W Dejonghe, ...
Proceedings of the National Academy of Sciences 118 (38), e2108281118, 2021
232021
Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2
AS Vaidya, B Karumudi, E Mendonca, A Madriaga, H Abdelkarim, ...
Bioorganic & medicinal chemistry letters 22 (15), 5025-5030, 2012
212012
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine‐based Histone Deacetylase Inhibitors
H Abdelkarim, R Neelarapu, A Madriaga, AS Vaidya, I Kastrati, ...
ChemMedChem 12 (24), 2030-2043, 2017
132017
Selective control of parasitic nematodes using bioactivated nematicides
AR Burns, RJ Baker, M Kitner, J Knox, B Cooke, JR Volpatti, AS Vaidya, ...
Nature 618 (7963), 102-109, 2023
102023
Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release
S Harrington, JJ Knox, AR Burns, KL Choo, A Au, M Kitner, C Haeberli, ...
Communications biology 5 (1), 865, 2022
52022
Chemical approaches for improving plant water use
AS Vaidya, SR Cutler
Abscisic Acid: Methods and Protocols, 221-230, 2022
52022
A luciferase reporter assay to identify chemical activators of ABA signaling
I García-Maquilón, PL Rodriguez, AS Vaidya, J Lozano-Juste
Plant Chemical Genomics: Methods and Protocols, 113-121, 2021
52021
An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity
SY Park, J Qiu, S Wei, FC Peterson, J Beltrán, AV Medina-Cucurella, ...
Nature Chemical Biology 20 (1), 103-110, 2024
42024
PYL10 bound to the ABA pan-antagonist 4a
FC Peterson, AS Vaidya, BF Volkman, SR Cutler
(No Title), 2021
22021
In Planta Labeling Using a Clickable ER-Disrupting Probe Suggests a Role for Oleosins in Arabidopsis Seedling ER Integrity
W Dejonghe, AS Vaidya, SE Alfred, SR Cutler
ACS Chemical Biology 16 (11), 2151-2157, 2021
22021
Synthesis and characterization of abscisic acid receptor modulators
AS Vaidya, SY Park, Z Xing, SR Cutler
Methods in Enzymology 671, 435-470, 2022
12022
Unusually potent ABA receptor pan-antagonists
SR Cutler, A Vaidya
US Patent 11,641,857, 2023
2023
Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release
S Harrington, JJ Knox, AR Burns, KL Choo, A Au, M Kitner, C Haeberli, ...
bioRxiv, 2022.03. 12.484074, 2022
2022
INAUGURAL ARTICLE by a Recently Elected Academy Member: Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo
AS Vaidya, FC Peterson, J Eckhardt, Z Xing, SY Park, W Dejonghe, ...
Proceedings of the National Academy of Sciences of the United States of …, 2021
2021
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