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Heng Lin
Heng Lin
Verified email at med.umich.edu
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Year
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression
H Lin, S Wei, EM Hurt, MD Green, L Zhao, L Vatan, W Szeliga, R Herbst, ...
The Journal of clinical investigation 128 (2), 805-815, 2018
5612018
Effector T cells abrogate stroma-mediated chemoresistance in ovarian cancer
W Wang, I Kryczek, L Dostál, H Lin, L Tan, L Zhao, F Lu, S Wei, T Maj, ...
Cell 165 (5), 1092-1105, 2016
3912016
DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial–mesenchymal transition in human breast cancer
Q Lv, W Wang, J Xue, F Hua, R Mu, H Lin, J Yan, X Lv, X Chen, ZW Hu
Cancer research 72 (13), 3238-3250, 2012
1822012
TRB3 interacts with SMAD3 promoting tumor cell migration and invasion
F Hua, R Mu, J Liu, J Xue, Z Wang, H Lin, H Yang, X Chen, Z Hu
Journal of cell science 124 (19), 3235-3246, 2011
1512011
TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations
F Hua, K Li, JJ Yu, XX Lv, J Yan, XW Zhang, W Sun, H Lin, S Shang, ...
Nature communications 6 (1), 7951, 2015
1432015
Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy
J Li, W Wang, Y Zhang, M Cieślik, J Guo, M Tan, MD Green, W Wang, ...
The Journal of clinical investigation 130 (5), 2712-2726, 2020
1282020
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy
G Li, I Kryczek, J Nam, X Li, S Li, J Li, S Wei, S Grove, L Vatan, J Zhou, ...
Nature cell biology 23 (5), 526-537, 2021
1152021
Loss of immunity‐supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll‐like receptor 2‐deficient mice
H Lin, J Yan, Z Wang, F Hua, J Yu, W Sun, K Li, H Liu, H Yang, Q Lv, ...
Hepatology 57 (1), 171-182, 2013
1102013
Blocking TLR2 activity attenuates pulmonary metastases of tumor
HZ Yang, B Cui, HZ Liu, S Mi, J Yan, HM Yan, F Hua, H Lin, WF Cai, ...
PloS one 4 (8), e6520, 2009
1092009
BCL6 induces EMT by promoting the ZEB1-mediated transcription repression of E-cadherin in breast cancer cells
JM Yu, W Sun, F Hua, J Xie, H Lin, DD Zhou, ZW Hu
Cancer letters 365 (2), 190-200, 2015
1012015
Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
H Lin, I Kryczek, S Li, MD Green, A Ali, R Hamasha, S Wei, L Vatan, ...
Cancer Cell 39 (4), 480-493. e6, 2021
912021
Autophagy and the immune response
B Cui, H Lin, J Yu, J Yu, Z Hu
Autophagy: Biology and Diseases: Basic Science, 595-634, 2019
882019
Toll‐like receptor 4 activity protects against hepatocellular tumorigenesis and progression by regulating expression of DNA repair protein Ku70 in mice
Z Wang, J Yan, H Lin, F Hua, X Wang, H Liu, X Lv, J Yu, S Mi, J Wang, ...
Hepatology 57 (5), 1869-1881, 2013
652013
The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity
J Zhou, I Kryczek, S Li, X Li, A Aguilar, S Wei, S Grove, L Vatan, J Yu, ...
Nature immunology 22 (4), 460-470, 2021
612021
A combined strategy improves the solubility of aggregation-prone single-chain variable fragment antibodies
W Sun, J Xie, H Lin, S Mi, Z Li, F Hua, Z Hu
Protein expression and purification 83 (1), 21-29, 2012
602012
Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse
H Lin, X Liu, J Yu, F Hua, Z Hu
PLoS One 8 (10), e74130, 2013
552013
Targeting acute myeloid leukemia with a proapoptotic peptide conjugated to a toll‐like receptor 2‐mediated cell‐penetrating peptide
K Li, XX Lv, F Hua, H Lin, W Sun, WB Cao, XM Fu, J Xie, JJ Yu, Z Li, H Liu, ...
International journal of cancer 134 (3), 692-702, 2014
542014
Repairing DNA damage by XRCC6/KU70 reverses TLR4-deficiency-worsened HCC development via restoring senescence and autophagic flux
Z Wang, H Lin, F Hua, Z Hu
Autophagy 9 (6), 925-927, 2013
532013
Autophagic flux, supported by toll-like receptor 2 activity, defends against the carcinogenesis of hepatocellular carcinoma
H Lin, F Hua, ZW Hu
Autophagy 8 (12), 1859-1861, 2012
372012
Glycogen synthase kinase-3β negatively regulates TGF-β1 and Angiotensin II-mediated cellular activity through interaction with Smad3
F Hua, J Zhou, J Liu, C Zhu, B Cui, H Lin, Y Liu, W Jin, H Yang, Z Hu
European journal of pharmacology 644 (1-3), 17-23, 2010
322010
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