| Protein structure prediction and structural genomics D Baker, A Sali Science 294 (5540), 93-96, 2001 | 1921 | 2001 |
| Design of a novel globular protein fold with atomic-level accuracy B Kuhlman, G Dantas, GC Ireton, G Varani, BL Stoddard, D Baker science 302 (5649), 1364-1368, 2003 | 1618 | 2003 |
| Contact order, transition state placement and the refolding rates of single domain proteins KW Plaxco, KT Simons, D Baker Journal of molecular biology 277 (4), 985-994, 1998 | 1610 | 1998 |
| Protein structure prediction using Rosetta CA Rohl, CEM Strauss, KMS Misura, D Baker Methods in enzymology 383, 66-93, 2004 | 1539 | 2004 |
| Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions KT Simons, C Kooperberg, E Huang, D Baker Journal of molecular biology 268 (1), 209-225, 1997 | 1450 | 1997 |
| Predicting protein structures with a multiplayer online game S Cooper, F Khatib, A Treuille, J Barbero, J Lee, M Beenen, A Leaver-Fay, ... Nature 466 (7307), 756-760, 2010 | 1390 | 2010 |
| Protein structure prediction and analysis using the Robetta server DE Kim, D Chivian, D Baker Nucleic acids research 32 (suppl_2), W526-W531, 2004 | 1229 | 2004 |
| Kemp elimination catalysts by computational enzyme design D Röthlisberger, O Khersonsky, AM Wollacott, L Jiang, J DeChancie, ... Nature 453 (7192), 190-195, 2008 | 1160 | 2008 |
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 1145 | 2011 |
| De novo computational design of retro-aldol enzymes L Jiang, EA Althoff, FR Clemente, L Doyle, D Röthlisberger, A Zanghellini, ... science 319 (5868), 1387-1391, 2008 | 1082 | 2008 |
| Protein–protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations JJ Gray, S Moughon, C Wang, O Schueler-Furman, B Kuhlman, CA Rohl, ... Journal of molecular biology 331 (1), 281-299, 2003 | 1027 | 2003 |
| A surprising simplicity to protein folding D Baker Nature 405 (6782), 39-42, 2000 | 927 | 2000 |
| Toward high-resolution de novo structure prediction for small proteins P Bradley, KMS Misura, D Baker Science 309 (5742), 1868-1871, 2005 | 916 | 2005 |
| Quantitative reactivity profiling predicts functional cysteines in proteomes E Weerapana, C Wang, GM Simon, F Richter, S Khare, MBD Dillon, ... Nature 468 (7325), 790-795, 2010 | 903 | 2010 |
| Pharmaco-metabonomic phenotyping and personalized drug treatment TA Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ... Nature 440 (7087), 1073-1077, 2006 | 849 | 2006 |
| Improving physical realism, stereochemistry, and side‐chain accuracy in homology modeling: four approaches that performed well in CASP8 E Krieger, K Joo, J Lee, J Lee, S Raman, J Thompson, M Tyka, D Baker, ... Proteins: Structure, Function, and Bioinformatics 77 (S9), 114-122, 2009 | 832 | 2009 |
| Native protein sequences are close to optimal for their structures B Kuhlman, D Baker Proceedings of the National Academy of Sciences 97 (19), 10383-10388, 2000 | 827 | 2000 |
| A simple physical model for binding energy hot spots in protein–protein complexes T Kortemme, D Baker Proceedings of the National Academy of Sciences 99 (22), 14116-14121, 2002 | 807 | 2002 |
| Macromolecular modeling with rosetta R Das, D Baker Annu. Rev. Biochem. 77, 363-382, 2008 | 803 | 2008 |
| Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction JB Siegel, A Zanghellini, HM Lovick, G Kiss, AR Lambert, JLS Clair, ... Science 329 (5989), 309-313, 2010 | 784 | 2010 |
Philip BradleyFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
