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Armin P. Schoech
Armin P. Schoech
Verifierad e-postadress på g.harvard.edu
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Leveraging polygenic functional enrichment to improve GWAS power
G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ...
The American Journal of Human Genetics 104 (1), 65-75, 2019
7992019
Mixed-model association for biobank-scale datasets
PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price
Nature genetics 50 (7), 906-908, 2018
5922018
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ...
Nature genetics 49 (10), 1421-1427, 2017
4122017
Functionally informed fine-mapping and polygenic localization of complex trait heritability
O Weissbrod, F Hormozdiari, C Benner, R Cui, J Ulirsch, S Gazal, ...
Nature genetics 52 (12), 1355-1363, 2020
2052020
Extreme polygenicity of complex traits is explained by negative selection
LJ O'Connor, AP Schoech, F Hormozdiari, S Gazal, N Patterson, AL Price
The American Journal of Human Genetics 105 (3), 456-476, 2019
2022019
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
F Hormozdiari, S Gazal, B Van De Geijn, HK Finucane, CJT Ju, PR Loh, ...
Nature genetics 50 (7), 1041-1047, 2018
1562018
Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations
S Gazal, PR Loh, HK Finucane, A Ganna, A Schoech, S Sunyaev, ...
Nature genetics 50 (11), 1600-1607, 2018
1422018
Population-specific causal disease effect sizes in functionally important regions impacted by selection
H Shi, S Gazal, M Kanai, EM Koch, AP Schoech, KM Siewert, SS Kim, ...
Nature communications 12 (1), 1098, 2021
1282021
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ...
Nature communications 10 (1), 790, 2019
1042019
The evolution of quorum sensing as a mechanism to infer kinship
J Schluter, AP Schoech, KR Foster, S Mitri
PLoS computational biology 12 (4), e1004848, 2016
742016
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits
AP Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
BioRxiv, 188086, 2017
222017
Facilitated diffusion buffers noise in gene expression
AP Schoech, NR Zabet
Physical Review E 90 (3), 032701, 2014
82014
Quantification of genetic components of population differentiation in UK Biobank traits reveals signals of polygenic selection
X Liu, PR Loh, LJ O’Connor, S Gazal, A Schoech, RM Maier, N Patterson, ...
Biorxiv, 357483, 2018
72018
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits
F Hormozdiari, S Gazal, B Geijn, H Finucane, CJT Ju, PR Loh, A Schoech, ...
bioRxiv, 203380, 2017
62017
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits. bioRxiv
A Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
September, 2017
62017
Mixed model association for biobank-scale data sets. bioRxiv
PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price
DOI: https://doi org/101101/194944, 2017
62017
Negative short-range genomic autocorrelation of causal effects on human complex traits
AP Schoech, O Weissbrod, LJ O’Connor, N Patterson, H Shi, Y Reshef, ...
bioRxiv, 2020.09. 23.310748, 2020
52020
Low-frequency variant functional architectures reveal strength of negative selection across coding and non-coding annotations
S Gazal, PR Loh, HK Finucane, A Ganna, A Schoech, S Sunyaev, ...
bioRxiv, 297572, 2018
32018
Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.
S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ...
Nature Genetics 51 (8), 1295-1295, 2019
12019
Statistical Inference of Signatures of Natural Selection in Human Complex Trait Genetic Architecture
AP Schoech
Harvard University, 2020
2020
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Artiklar 1–20