Huimin Geng
Huimin Geng
Associate Adjunct Professor, UCSF
Verified email at
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A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy
WWL Choi, DD Weisenburger, TC Greiner, MA Piris, AH Banham, ...
Clinical cancer research 15 (17), 5494-5502, 2009
Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma
J Iqbal, DD Weisenburger, TC Greiner, JM Vose, T McKeithan, C Kucuk, ...
Blood, The Journal of the American Society of Hematology 115 (5), 1026-1036, 2010
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
I Velichutina, R Shaknovich, H Geng, NA Johnson, RD Gascoyne, ...
Blood, The Journal of the American Society of Hematology 116 (24), 5247-5255, 2010
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ...
Cancer discovery 7 (1), 38-53, 2017
TET1 is a tumor suppressor of hematopoietic malignancy
L Cimmino, MM Dawlaty, D Ndiaye-Lobry, YS Yap, S Bakogianni, Y Yu, ...
Nature immunology 16 (6), 653-662, 2015
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ...
Nature 473 (7347), 384-388, 2011
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
S Swaminathan, L Klemm, E Park, E Papaemmanuil, A Ford, SM Kweon, ...
Nature immunology 16 (7), 766-774, 2015
Metabolic gatekeeper function of B-lymphoid transcription factors
LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ...
Nature 542 (7642), 479-483, 2017
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
J Iqbal, C Kucuk, RJ Deleeuw, G Srivastava, W Tam, H Geng, D Klinkebiel, ...
Leukemia 23 (6), 1139-1151, 2009
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma
R Shaknovich, H Geng, NA Johnson, L Tsikitas, L Cerchietti, JM Greally, ...
Blood, The Journal of the American Society of Hematology 116 (20), e81-e89, 2010
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile
K Cramer-Morales, M Nieborowska-Skorska, K Scheibner, M Padget, ...
Blood, The Journal of the American Society of Hematology 122 (7), 1293-1304, 2013
Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma
JL Rubenstein, H Geng, EJ Fraser, P Formaker, L Chen, J Sharma, ...
Blood advances 2 (13), 1595-1607, 2018
RUNX1 is a key target in t (4; 11) leukemias that contributes to gene activation through an AF4-MLL complex interaction
AC Wilkinson, E Ballabio, H Geng, P North, M Tapia, J Kerry, D Biswas, ...
Cell reports 3 (1), 116-127, 2013
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma
MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ...
The Journal of clinical investigation 126 (9), 3351-3362, 2016
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia
Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ...
Nature 521 (7552), 357-361, 2015
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199
JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ...
Cell reports 13 (12), 2715-2727, 2015
Metal ion-directed functional metal–phenolic materials
H Geng, QZ Zhong, J Li, Z Lin, J Cui, F Caruso, J Hao
Chemical Reviews 122 (13), 11432-11473, 2022
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy
YT Hsieh, EJ Gang, H Geng, E Park, S Huantes, D Chudziak, K Dauber, ...
Blood, The Journal of the American Society of Hematology 121 (10), 1814-1818, 2013
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity
S De, R Shaknovich, M Riester, O Elemento, H Geng, M Kormaksson, ...
PLoS genetics 9 (1), e1003137, 2013
Erk negative feedback control enables pre-B cell transformation and represents a therapeutic target in acute lymphoblastic leukemia
S Shojaee, R Caeser, M Buchner, E Park, S Swaminathan, C Hurtz, ...
Cancer cell 28 (1), 114-128, 2015
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