ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ... Neuron 88 (4), 678-690, 2015 | 816 | 2015 |
ANS binding reveals common features of cytotoxic amyloid species B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, ... ACS chemical biology 5 (8), 735-740, 2010 | 415 | 2010 |
Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils M Cheon, I Chang, S Mohanty, LM Luheshi, CM Dobson, M Vendruscolo, ... PLoS computational biology 3 (9), e173, 2007 | 256 | 2007 |
Oligomerization of amyloid Aβ16–22 peptides using hydrogen bonds and hydrophobicity forces G Favrin, A Irbäck, S Mohanty Biophysical Journal 87 (6), 3657-3664, 2004 | 165 | 2004 |
Monte Carlo update for chain molecules: biased Gaussian steps in torsional space G Favrin, A Irbäck, F Sjunnesson The Journal of Chemical Physics 114 (18), 8154-8158, 2001 | 130 | 2001 |
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS P Ciryam, IA Lambert-Smith, DM Bean, R Freer, F Cid, GG Tartaglia, ... Proceedings of the National Academy of Sciences 114 (20), E3935-E3943, 2017 | 110 | 2017 |
Folding of a small helical protein using hydrogen bonds and hydrophobicity forces G Favrin, A Irbäck, S Wallin Proteins: Structure, Function, and Bioinformatics 47 (2), 99-105, 2002 | 90 | 2002 |
esyN: network building, sharing and publishing DM Bean, J Heimbach, L Ficorella, G Micklem, SG Oliver, G Favrin PloS one 9 (9), e106035, 2014 | 66 | 2014 |
Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity E Speretta, TR Jahn, GG Tartaglia, G Favrin, TP Barros, S Imarisio, ... Journal of Biological Chemistry 287 (24), 20748-20754, 2012 | 61 | 2012 |
Intrinsic determinants of neurotoxic aggregate formation by the amyloid β peptide AC Brorsson, B Bolognesi, GG Tartaglia, SL Shammas, G Favrin, I Watson, ... Biophysical journal 98 (8), 1677-1684, 2010 | 59 | 2010 |
The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans E Khabirova, A Moloney, SJ Marciniak, J Williams, DA Lomas, SG Oliver, ... PloS one 9 (7), e102985, 2014 | 43 | 2014 |
A Monte Carlo approach for assessing the specificity of protein oligomers observed in nano-electrospray mass spectra LA Lane, BT Ruotolo, CV Robinson, G Favrin, JLP Benesch International Journal of Mass Spectrometry 283 (1-3), 169-177, 2009 | 39 | 2009 |
Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer's disease PM McKeever, TH Kim, AR Hesketh, L MacNair, D Miletic, G Favrin, ... Neurobiology of aging 57, 104-119, 2017 | 36 | 2017 |
Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly G Favrin, DM Bean, E Bilsland, H Boyer, BE Fischer, S Russell, ... Scientific Reports 3 (1), 3512, 2013 | 24 | 2013 |
Two-state folding over a weak free-energy barrier G Favrin, A Irbäck, B Samuelsson, S Wallin Biophysical journal 85 (3), 1457-1465, 2003 | 17 | 2003 |
Calculation of the free energy barriers in the oligomerisation of Abeta peptide fragments M Cheon, G Favrin, I Chang, CM Dobson, M Vendruscolo Front Biosci 13, 5614-5622, 2008 | 16 | 2008 |
Finite size effects in simulations of protein aggregation A Pawar, G Favrin PLoS One 3 (7), e2641, 2008 | 9 | 2008 |
Network approaches to the understanding of Alzheimer’s disease: from model organisms to humans J Yerbury, D Bean, G Favrin Systems Biology of Alzheimer's Disease, 447-458, 2016 | 6 | 2016 |
Sequence‐based study of two related proteins with different folding behaviors G Favrin, A Irbäck, S Wallin Proteins: Structure, Function, and Bioinformatics 54 (1), 8-12, 2004 | 5 | 2004 |
Big data approaches to dementia: Opportunities and challenges G Anderson, R Buckle, G Favrin, S Friend, D Geschwind, H Hu, S Oliver, ... Dementia Research and Care, 39, 2015 | 2 | 2015 |