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PROF. DR. AJDA GURKAN
PROF. DR. AJDA GURKAN
Verifierad e-postadress på marmara.edu.tr
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Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells
Y Akkoç, Ö Berrak, ED Arısan, P Obakan, A Çoker-Gürkan, ...
Biomedicine & Pharmacotherapy 71, 161-171, 2015
792015
The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells
Ö Berrak, Y Akkoç, ED Arısan, A Çoker-Gürkan, P Obakan-Yerlikaya, ...
Biomedicine & Pharmacotherapy 77, 150-160, 2016
692016
Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-κB signaling and polyamine metabolism in breast cancer cells
A Coker-Gurkan, M Celik, M Ugur, ED Arisan, P Obakan-Yerlikaya, ...
Amino acids 50, 1045-1069, 2018
542018
Interleukin-1 receptor antagonist (IL-1RN) and interleukin-1B gene polymorphisms in Turkish patients with rheumatoid arthritis
A Arman, B Yilmaz, A Coker, N Inanc, H Direskeneli
Clin Exp Rheumatol 24 (6), 643-8, 2006
532006
Cathepsin K analysis in a pycnodysostosis cohort: demographic, genotypic and phenotypic features
A Arman, A Bereket, A Coker, PÖŞ Kiper, T Güran, B Özkan, Z Atay, ...
Orphanet journal of rare diseases 9, 1-8, 2014
492014
CDK inhibitors induce mitochondria-mediated apoptosis through the activation of polyamine catabolic pathway in LNCaP, DU145 and PC3 prostate cancer cells
E Damla Arisan, P Obakan, A Coker-Gurkan, A Calcabrini, E Agostinelli, ...
Current pharmaceutical design 20 (2), 180-188, 2014
472014
Interleukin-1 receptor antagonist gene VNTR polymorphism is associated with coronary artery disease
A Arman, O Soylu, A Yildirim, A Furman, N Ercelen, H Aydogan, A Coker, ...
Arquivos brasileiros de cardiologia 91, 293-298, 2008
432008
Assessment of Interleukin‐1 Gene Cluster Polymorphisms in Lone Atrial Fibrillation: New Insight into the Role of Inflammation in Atrial Fibrillation
B Gungor, A Ekmekci, A Arman, KS Ozcan, E Ucer, AT Alper, N Calik, ...
Pacing and Clinical Electrophysiology 36 (10), 1220-1227, 2013
422013
Curcumin prevented human autocrine growth hormone (GH) signaling mediated NF-κB activation and miR-183-96-182 cluster stimulated epithelial mesenchymal transition in T47D …
A Coker-Gurkan, D Bulut, R Genc, ED Arisan, P Obakan-Yerlikaya, ...
Molecular biology reports 46 (1), 355-369, 2019
412019
Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells
A Coker-Gurkan, ED Arisan, P Obakan, E Guvenir, NP Unsal
Experimental Cell Research 328 (1), 87-98, 2014
402014
Lack of association between IL‐1 and IL‐6 gene polymorphisms and myocardial infarction in Turkish population
A Çoker, A Arman, O Soylu, T Tezel, A Yildirim
International Journal of Immunogenetics 38 (3), 201-208, 2011
392011
Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells
D Coskun, P Obakan, ED Arisan, A Çoker-Gürkan, N Palavan-Ünsal
Experimental cell research 338 (1), 10-21, 2015
372015
Polyamine depletion enhances the roscovitine-induced apoptosis through the activation of mitochondria in HCT116 colon carcinoma cells
ED Arısan, A Çoker, N Palavan-Ünsal
Amino Acids 42, 655-665, 2012
342012
Calreticulin is a fine tuning molecule in epibrassinolide‐induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells
P Obakan‐Yerlikaya, ED Arisan, A Coker‐Gurkan, K Adacan, U Ozbey, ...
Molecular Carcinogenesis 56 (6), 1603-1619, 2017
322017
Diclofenac induced apoptosis via altering PI3K/Akt/MAPK signaling axis in HCT 116 more efficiently compared to SW480 colon cancer cells
ED Arisan, Z Ergül, G Bozdağ, Ö Rencüzoğulları, A Çoker-Gürkan, ...
Molecular biology reports 45 (6), 2175-2184, 2018
302018
Epibrassinolide‐induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate …
P Obakan, ED Arisan, A Coker‐Gurkan, N Palavan‐Unsal
The Prostate 74 (16), 1622-1633, 2014
302014
Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population
A Arman, A Coker, O Sarioz, N Inanc, H Direskeneli
Rheumatology international 32, 2199-2201, 2012
302012
Palbociclib, a selective CDK4/6 inhibitor, restricts cell survival and epithelial‐mesenchymal transition in Panc‐1 and MiaPaCa‐2 pancreatic cancer cells
O Rencuzogulları, PO Yerlikaya, AÇ Gürkan, ED Arısan, D Telci
Journal of cellular biochemistry 121 (1), 508-523, 2020
272020
Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells
E Damla Arisan, P Obakan, A Coker, N Palavan-Unsal
Molecular Medicine Reports 5 (5), 1323-1329, 2012
272012
SILAC-based mass spectrometry analysis reveals that epibrassinolide induces apoptosis via activating endoplasmic reticulum stress in prostate cancer cells
P Obakan, C Barrero, A Coker-Gurkan, ED Arisan, S Merali, ...
PLoS One 10 (9), e0135788, 2015
262015
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