|Mechanisms of photoaging and chronological skin aging|
GJ Fisher, S Kang, J Varani, Z Bata-Csorgo, Y Wan, S Datta, JJ Voorhees
Archives of dermatology 138 (11), 1462-1470, 2002
|Molecular basis of sun-induced premature skin ageing and retinoid antagonism|
GJ Fisher, SC Datta, HS Talwar, ZQ Wang, J Varani, S Kang, JJ Voorhees
Nature 379 (6563), 335-339, 1996
|Pathophysiology of premature skin aging induced by ultraviolet light|
GJ Fisher, ZQ Wang, SC Datta, J Varani, S Kang, JJ Voorhees
New England Journal of Medicine 337 (20), 1419-1429, 1997
|Vitamin a antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin1|
J Varani, RL Warner, M Gharaee-Kermani, SH Phan, S Kang, JH Chung, ...
Journal of Investigative Dermatology 114 (3), 480-486, 2000
|Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation|
J Varani, MK Dame, L Rittie, SEG Fligiel, S Kang, GJ Fisher, JJ Voorhees
The American journal of pathology 168 (6), 1861-1868, 2006
|Looking older: fibroblast collapse and therapeutic implications|
GJ Fisher, J Varani, JJ Voorhees
Archives of dermatology 144 (5), 666-672, 2008
|Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.|
MS Mulligan, J Varani, MK Dame, CL Lane, CW Smith, DC Anderson, ...
The Journal of clinical investigation 88 (4), 1396-1406, 1991
|In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin|
F Wang, LA Garza, S Kang, J Varani, JS Orringer, GJ Fisher, JJ Voorhees
Archives of Dermatology 143 (2), 155-163, 2007
|Effects of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts|
T Yamamoto, J Varani, HK Soong, PR Lighter
Ophthalmology 97 (9), 1204-1210, 1990
|Matrix Metalloproteinase‐1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV‐irradiated Human Skin¶|
M Brennan, H Bhatti, KC Nerusu, N Bhagavathula, S Kang, GJ Fisher, ...
Photochemistry and photobiology 78 (1), 43-48, 2003
|Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin|
GJ Fisher, T Quan, T Purohit, Y Shao, MK Cho, T He, J Varani, S Kang, ...
The American journal of pathology 174 (1), 101-114, 2009
|Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro|
J Varani, D Spearman, P Perone, SEG Fligiel, SC Datta, ZQ Wang, ...
The American journal of pathology 158 (3), 931-942, 2001
|Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.|
J Varani, SE Fligiel, GO Till, RG Kunkel, US Ryan, PA Ward
Laboratory investigation; a journal of technical methods and pathology 53 (6 …, 1985
|Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor‐stimulated human epidermal keratinocytes|
ME Zeigler, Y Chi, T Schmidt, J Varani
Journal of cellular physiology 180 (2), 271-284, 1999
|Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-γ inhibit keratinocyte proliferation|
CN Ellis, J Varani, GJ Fisher, ME Zeigler, HA Pershadsingh, SC Benson, ...
Archives of Dermatology 136 (5), 609-616, 2000
|Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.|
BJ Nickoloff, RS Mitra, J Varani, VM Dixit, PJ Polverini
The American journal of pathology 144 (4), 820, 1994
|Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro|
SEG Fligiel, J Varani, SC Datta, S Kang, GJ Fisher, JJ Voorhees
Journal of Investigative Dermatology 120 (5), 842-848, 2003
|Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases.|
J Varani, I Ginsburg, L Schuger, DF Gibbs, J Bromberg, KJ Johnson, ...
The American journal of pathology 135 (3), 435, 1989
|Improvement of naturally aged skin with vitamin a (retinol)|
R Kafi, HSR Kwak, WE Schumacher, S Cho, VN Hanft, TA Hamilton, ...
Archives of dermatology 143 (5), 606-612, 2007
|Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of β-catenin/TCF activation|
S Chakrabarty, V Radjendirane, H Appelman, J Varani
Cancer research 63 (1), 67-71, 2003