| Harnessing conformational plasticity to generate designer enzymes RM Crean, JM Gardner, SCL Kamerlin Journal of the American Chemical Society 142 (26), 11324-11342, 2020 | 83 | 2020 |
| Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA CJ Holland, RM Crean, JM Pentier, B de Wet, A Lloyd, V Srikannathasan, ... The Journal of clinical investigation 130 (5), 2673-2688, 2020 | 56 | 2020 |
| Loop dynamics and enzyme catalysis in protein tyrosine phosphatases RM Crean, M Biler, MW van der Kamp, AC Hengge, SCL Kamerlin Journal of the American Chemical Society 143 (10), 3830-3845, 2021 | 49 | 2021 |
| Uncovering the relationship between the change in heat capacity for enzyme catalysis and vibrational frequency through isotope effect studies HBL Jones, RM Crean, C Matthews, AB Troya, MJ Danson, SD Bull, ... ACS Catalysis 8 (6), 5340-5349, 2018 | 20 | 2018 |
| Single residue on the WPD-loop affects the pH dependency of catalysis in protein tyrosine phosphatases R Shen, RM Crean, SJ Johnson, SCL Kamerlin, AC Hengge JACS Au 1 (5), 646-659, 2021 | 19 | 2021 |
| Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases R Shen, RM Crean, KJ Olsen, M Corbella, AR Calixto, T Richan, ... Chemical Science 13 (45), 13524-13540, 2022 | 15 | 2022 |
| Exposing the interplay between enzyme turnover, protein dynamics, and the membrane environment in monoamine oxidase B HBL Jones, RM Crean, A Mullen, EG Kendrick, SD Bull, SA Wells, ... Biochemistry 58 (18), 2362-2372, 2019 | 13 | 2019 |
| Molecular rules underpinning enhanced affinity binding of human T cell receptors engineered for immunotherapy RM Crean, BJ MacLachlan, F Madura, T Whalley, PJ Rizkallah, ... Molecular Therapy-Oncolytics 18, 443-456, 2020 | 12 | 2020 |
| Reliable In Silico Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA RM Crean, CR Pudney, DK Cole, MW Van der Kamp Journal of Chemical Information and Modeling 62 (3), 577-590, 2022 | 9 | 2022 |
| Peptide cargo tunes a network of correlated motions in human leucocyte antigens JR Hopkins, RM Crean, DAM Catici, AK Sewell, VL Arcus, ... The FEBS Journal 287 (17), 3777-3793, 2020 | 8 | 2020 |
| Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover SD Winter, HBL Jones, DM Răsădean, RM Crean, MJ Danson, ... ACS catalysis 11 (24), 14854-14863, 2021 | 7 | 2021 |
| Ground-state destabilization by active-site hydrophobicity controls the selectivity of a cofactor-free decarboxylase M Biler, RM Crean, AK Schweiger, R Kourist, SCL Kamerlin Journal of the American Chemical Society 142 (47), 20216-20231, 2020 | 7 | 2020 |
| Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses A Chancellor, R Alan Simmons, RC Khanolkar, V Nosi, A Beshirova, ... Journal of Experimental Medicine 220 (9), e20221939, 2023 | 4 | 2023 |
| KIF—key interactions finder: a program to identify the key molecular interactions that regulate protein conformational changes RM Crean, JSG Slusky, PM Kasson, SCL Kamerlin The Journal of Chemical Physics 158 (14), 2023 | 4 | 2023 |
| Correction to “Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases” RM Crean, M Biler, M Corbella, AR Calixto, MW van der Kamp, ... Journal of the American Chemical Society 144 (22), 10091-10093, 2022 | 4 | 2022 |
| Essential functional interplay of the catalytic groups in acid phosphatase M Pfeiffer, RM Crean, C Moreira, A Parracino, G Oberdorfer, L Brecker, ... ACS catalysis 12 (6), 3357-3370, 2022 | 4 | 2022 |
| Cooperative Conformational Transitions Underpin the Activation Heat Capacity in the Temperature Dependence of Enzyme Catalysis EJ Walker, CJ Hamill, R Crean, MS Connolly, AK Warrender, ... ACS catalysis 14 (7), 4379-4394, 2024 | 1 | 2024 |
| Key interaction networks: Identifying evolutionarily conserved non‐covalent interaction networks across protein families D Yehorova, RM Crean, PM Kasson, SCL Kamerlin Protein Science 33 (3), e4911, 2024 | 1 | 2024 |
| Sequence–Dynamics–Function Relationships in Protein Tyrosine Phosphatases RM Crean, M Corbella, AR Calixto, AC Hengge, SCL Kamerlin QRB Discovery, 1-37, 2023 | 1 | 2023 |
| Friends and Relatives: Insight Into Conformational Regulation from Orthologues and Evolutionary Lineages using KIF and KIN D Yehorova, RM Crean, PM Kasson, SCL Kamerlin Faraday Discussions, 2024 | | 2024 |
Kamerlin SC*Georgia Institute of TechnologyVerified email at gatech.edu
