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Alberto Lleo
Alberto Lleo
Neurology Department. Hospital Sant Pau. Barcelona.
Verifierad e-postadress på santpau.es - Startsida
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
43342013
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21662019
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
14862015
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
8982017
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
8522022
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ...
Science translational medicine 6 (243), 243ra86-243ra86, 2014
7312014
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
R Ossenkoppele, WJ Jansen, GD Rabinovici, DL Knol, WM van der Flier, ...
Jama 313 (19), 1939-1950, 2015
6232015
Current pharmacotherapy for Alzheimer's disease
A Lleo, SM Greenberg, JH Growdon
Annu. Rev. Med. 57, 513-533, 2006
4952006
sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
M Suárez‐Calvet, G Kleinberger, MÁ Araque Caballero, M Brendel, ...
EMBO molecular medicine 8 (5), 466-476, 2016
4482016
A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo
L Serenó, M Coma, M Rodriguez, P Sánchez-Ferrer, MB Sánchez, I Gich, ...
Neurobiology of disease 35 (3), 359-367, 2009
4092009
CSF biomarker variability in the Alzheimer's Association quality control program
N Mattsson, U Andreasson, S Persson, MC Carrillo, S Collins, S Chalbot, ...
Alzheimer's & Dementia 9 (3), 251-261, 2013
3972013
Frontotemporal dementia and its subtypes: a genome-wide association study
R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ...
The Lancet Neurology 13 (7), 686-699, 2014
3722014
Consensus guidelines for lumbar puncture in patients with neurological diseases
S Engelborghs, E Niemantsverdriet, H Struyfs, K Blennow, R Brouns, ...
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 8, 111-126, 2017
3142017
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging …
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nat Genet 45 (12), 1452-1458, 2013
2912013
A novel Alzheimer disease locus located near the gene encoding tau protein
G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ...
Molecular psychiatry 21 (1), 108-117, 2016
2862016
Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation
A Lleó, O Berezovska, L Herl, S Raju, A Deng, BJ Bacskai, MP Frosch, ...
Nature medicine 10 (10), 1065-1066, 2004
2822004
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
2712021
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP
RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ...
Neurobiology of aging 31 (5), 725-731, 2010
2502010
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World …
P Lewczuk, P Riederer, SE O’bryant, MM Verbeek, B Dubois, PJ Visser, ...
The world journal of biological psychiatry 19 (4), 244-328, 2018
2462018
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study
R Guerreiro, OA Ross, C Kun-Rodrigues, DG Hernandez, T Orme, ...
The Lancet Neurology 17 (1), 64-74, 2018
2352018
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