Philip Cole
Philip Cole
Professor, Harvard Medical School and Brigham and Women's Hospital
Verifierad e-postadress på bwh.harvard.edu - Startsida
Titel
Citeras av
Citeras av
År
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
Y Shi, F Lan, C Matson, P Mulligan, JR Whetstine, PA Cole, RA Casero, ...
Cell 119 (7), 941-953, 2004
38912004
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
X Zhang, J Gureasko, K Shen, PA Cole, J Kuriyan
Cell 125 (6), 1137-1149, 2006
14532006
Expressed protein ligation: a general method for protein engineering
TW Muir, D Sondhi, PA Cole
Proceedings of the National Academy of Sciences 95 (12), 6705-6710, 1998
12901998
Acetylation of tau inhibits its degradation and contributes to tauopathy
SW Min, SH Cho, Y Zhou, S Schroeder, V Haroutunian, WW Seeley, ...
Neuron 67 (6), 953-966, 2010
6612010
Ghrelin
TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ...
Molecular metabolism 4 (6), 437-460, 2015
5302015
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Y Liu, R Dentin, D Chen, S Hedrick, K Ravnskjaer, S Schenk, J Milne, ...
Nature 456 (7219), 269-273, 2008
5172008
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor
EM Bowers, G Yan, C Mukherjee, A Orry, L Wang, MA Holbert, NT Crump, ...
Chemistry & biology 17 (5), 471-482, 2010
5092010
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency‐associated genes
P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ...
Stem cells 28 (4), 713-720, 2010
4452010
HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF
OD Lau, TK Kundu, RE Soccio, S Ait-Si-Ali, EM Khalil, A Vassilev, ...
Molecular cell 5 (3), 589-595, 2000
3962000
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole
Nature 451 (7180), 846-850, 2008
3862008
Regulation of the p300 HAT domain via a novel activation loop
PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ...
Nature structural & molecular biology 11 (4), 308-315, 2004
3862004
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes
A Costanzo, P Merlo, N Pediconi, M Fulco, V Sartorelli, PA Cole, ...
Molecular cell 9 (1), 175-186, 2002
3742002
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
X Zhang, KA Pickin, R Bose, N Jura, PA Cole, J Kuriyan
Nature 450 (7170), 741-744, 2007
3302007
Mechanism and inhibition of cytochrome P-450 aromatase
PA Cole, CH Robinson
Journal of medicinal chemistry 33 (11), 2933-2942, 1990
3121990
A Src-like inactive conformation in the abl tyrosine kinase domain
NM Levinson, O Kuchment, K Shen, MA Young, M Koldobskiy, M Karplus, ...
PLoS Biol 4 (5), e144, 2006
2942006
Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling
W Lu, D Gong, D Bar-Sagi, PA Cole
Molecular cell 8 (4), 759-769, 2001
2762001
Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor
BP Barnett, Y Hwang, MS Taylor, H Kirchner, PT Pfluger, V Bernard, Y Lin, ...
Science 330 (6011), 1689-1692, 2010
2582010
Chemical probes for histone-modifying enzymes
PA Cole
Nature chemical biology 4 (10), 590-597, 2008
2562008
Mechanism-based design of a protein kinase inhibitor
K Parang, JH Till, AJ Ablooglu, RA Kohanski, SR Hubbard, PA Cole
Nature structural biology 8 (1), 37-41, 2001
2512001
Phosphoproteomic analysis of Her2/neu signaling and inhibition
R Bose, H Molina, AS Patterson, JK Bitok, B Periaswamy, JS Bader, ...
Proceedings of the National Academy of Sciences 103 (26), 9773-9778, 2006
2372006
Systemet kan inte utföra åtgärden just nu. Försök igen senare.
Artiklar 1–20