Gunnar Keppler Gouras
Gunnar Keppler Gouras
Professor of Experimental Neurology, Lund University
Verifierad e-postadress på med.lu.se - Startsida
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Regulation of NMDA receptor trafficking by amyloid-β
EM Snyder, Y Nong, CG Almeida, S Paul, T Moran, EY Choi, AC Nairn, ...
Nature neuroscience 8 (8), 1051-1058, 2005
16342005
Intraneuronal Aβ42 accumulation in human brain
GK Gouras, J Tsai, J Naslund, B Vincent, M Edgar, F Checler, ...
The American journal of pathology 156 (1), 15-20, 2000
11092000
Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
RH Takahashi, TA Milner, F Li, EE Nam, MA Edgar, H Yamaguchi, ...
The American journal of pathology 161 (5), 1869-1879, 2002
7112002
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
H Xu, GK Gouras, JP Greenfield, B Vincent, J Naslund, L Mazzarelli, ...
Nature medicine 4 (4), 447-451, 1998
6101998
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
L Gasparini, GK Gouras, R Wang, RS Gross, MF Beal, P Greengard, H Xu
Journal of Neuroscience 21 (8), 2561-2570, 2001
5412001
Oligomerization of Alzheimer's β-amyloid within processes and synapses of cultured neurons and brain
RH Takahashi, CG Almeida, PF Kearney, F Yu, MT Lin, TA Milner, ...
Journal of Neuroscience 24 (14), 3592-3599, 2004
4792004
Chaperones increase association of tau protein with microtubules
F Dou, WJ Netzer, K Tanemura, F Li, FU Hartl, A Takashima, GK Gouras, ...
Proceedings of the National Academy of Sciences 100 (2), 721-726, 2003
4792003
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
JP Greenfield, J Tsai, GK Gouras, B Hai, G Thinakaran, F Checler, ...
Proceedings of the National Academy of Sciences 96 (2), 742-747, 1999
4391999
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
CG Almeida, D Tampellini, RH Takahashi, P Greengard, MT Lin, ...
Neurobiology of disease 20 (2), 187-198, 2005
3902005
Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides
GK Gouras, H Xu, RS Gross, JP Greenfield, B Hai, R Wang, P Greengard
Proceedings of the national academy of sciences 97 (3), 1202-1205, 2000
3742000
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
GK Gouras, CG Almeida, RH Takahashi
Neurobiology of aging 26 (9), 1235-1244, 2005
3502005
Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
GK Gouras, D Tampellini, RH Takahashi, E Capetillo-Zarate
Acta neuropathologica 119 (5), 523-541, 2010
3382010
β-Amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system
CG Almeida, RH Takahashi, GK Gouras
Journal of Neuroscience 26 (16), 4277-4288, 2006
2922006
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
F Li, NY Calingasan, F Yu, WM Mauck, M Toidze, CG Almeida, ...
Journal of neurochemistry 89 (5), 1308-1312, 2004
2782004
Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease
T Ma, CA Hoeffer, E Capetillo-Zarate, F Yu, H Wong, MT Lin, D Tampellini, ...
PloS one 5 (9), e12845, 2010
2022010
Evidence for phosphorylation and oligomeric assembly of presenilin 1
M Seeger, C Nordstedt, S Petanceska, DM Kovacs, GK Gouras, S Hahne, ...
Proceedings of the National Academy of Sciences 94 (10), 5090-5094, 1997
1811997
Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein …
CA Saura, G Chen, S Malkani, SY Choi, RH Takahashi, D Zhang, ...
Journal of Neuroscience 25 (29), 6755-6764, 2005
1682005
Plaque formation and the intraneuronal accumulation of β‐amyloid in Alzheimer's disease
RH Takahashi, T Nagao, GK Gouras
Pathology international 67 (4), 185-193, 2017
1522017
Generation and regulation of β‐amyloid peptide variants by neurons
GK Gouras, H Xu, JN Jovanovic, JD Buxbaum, R Wang, P Greengard, ...
Journal of neurochemistry 71 (5), 1920-1925, 1998
1431998
Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses
RH Takahashi, E Capetillo-Zarate, MT Lin, TA Milner, GK Gouras
Neurobiology of aging 31 (7), 1145-1152, 2010
1372010
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