Andrea Fleig, PhD MBA
Andrea Fleig, PhD MBA
Associate Director of Biomedical Research, The Queen's Medical Center
Verifierad e-postadress på hawaii.edu - Startsida
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CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
M Vig, C Peinelt, A Beck, DL Koomoa, D Rabah, M Koblan-Huberson, ...
Science 312 (5777), 1220-1223, 2006
13812006
LTRPC7 is a Mg· ATP-regulated divalent cation channel required for cell viability
MJS Nadler, MC Hermosura, K Inabe, AL Perraud, Q Zhu, AJ Stokes, ...
Nature 411 (6837), 590-595, 2001
9052001
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
AL Perraud, A Fleig, CA Dunn, LA Bagley, P Launay, C Schmitz, ...
Nature 411 (6837), 595-599, 2001
8772001
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7
C Schmitz, AL Perraud, CO Johnson, K Inabe, MK Smith, R Penner, ...
Cell 114 (2), 191-200, 2003
6892003
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization
P Launay, A Fleig, AL Perraud, AM Scharenberg, R Penner, JP Kinet
Cell 109 (3), 397-407, 2002
6612002
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
C Peinelt, M Vig, DL Koomoa, A Beck, MJS Nadler, M Koblan-Huberson, ...
Nature cell biology 8 (7), 771-773, 2006
6292006
CRACM1 multimers form the ion-selective pore of the CRAC channel
M Vig, A Beck, JM Billingsley, A Lis, S Parvez, C Peinelt, DL Koomoa, ...
Current Biology 16 (20), 2073-2079, 2006
6072006
TRPM2-mediated Ca 2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
S Yamamoto, S Shimizu, S Kiyonaka, N Takahashi, T Wajima, Y Hara, ...
Nature medicine 14 (7), 738-747, 2008
4872008
TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions
MK Monteilh-Zoller, MC Hermosura, MJS Nadler, AM Scharenberg, ...
The Journal of general physiology 121 (1), 49-60, 2003
4802003
CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties
A Lis, C Peinelt, A Beck, S Parvez, M Monteilh-Zoller, A Fleig, R Penner
Current Biology 17 (9), 794-800, 2007
4122007
TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+] i
D Prawitt, MK Monteilh-Zoller, L Brixel, C Spangenberg, B Zabel, A Fleig, ...
Proceedings of the national academy of sciences 100 (25), 15166-15171, 2003
3442003
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
M Kolisek, A Beck, A Fleig, R Penner
Molecular cell 18 (1), 61-69, 2005
3182005
CaT1 and the calcium release-activated calcium channel manifest distinct pore properties
T Voets, J Prenen, A Fleig, R Vennekens, H Watanabe, JGJ Hoenderop, ...
Journal of Biological Chemistry 276 (51), 47767-47770, 2001
2742001
TRPM4 regulates calcium oscillations after T cell activation
P Launay, H Cheng, S Srivatsan, R Penner, A Fleig, JP Kinet
Science 306 (5700), 1374-1377, 2004
2712004
The TRPM ion channel subfamily: molecular, biophysical and functional features
A Fleig, R Penner
Trends in pharmacological sciences 25 (12), 633-639, 2004
2702004
TRPM7 is essential for Mg 2+ homeostasis in mammals
LV Ryazanova, LJ Rondon, S Zierler, Z Hu, J Galli, TP Yamaguchi, ...
Nature communications 1 (1), 1-9, 2010
2552010
The store-operated calcium current ICRAC: nonlinear activation by InsP3 and dissociation from calcium release
AB Parekh, A Fleig, R Penner
Cell 89 (6), 973-980, 1997
2551997
TRPM2 functions as a lysosomal Ca2+-release channel in β cells
I Lange, S Yamamoto, S Partida-Sanchez, Y Mori, A Fleig, R Penner
Science signaling 2 (71), ra23-ra23, 2009
2522009
Transient Receptor Potential 1 Regulates Capacitative Ca2+ Entry and Ca2+ Release from Endoplasmic Reticulum in B Lymphocytes
Y Mori, M Wakamori, T Miyakawa, M Hermosura, Y Hara, M Nishida, ...
The Journal of experimental medicine 195 (6), 673-681, 2002
2322002
Dissociation of the store‐operated calcium current ICRAC and the Mg‐nucleotide‐regulated metal ion current MagNuM
MC Hermosura, MK Monteilh‐Zoller, AM Scharenberg, R Penner, A Fleig
The Journal of physiology 539 (2), 445-458, 2002
2122002
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