| Playing the end game: DNA double-strand break repair pathway choice JR Chapman, MRG Taylor, SJ Boulton Molecular cell 47 (4), 497-510, 2012 | 1296 | 2012 |
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ... Science 318 (5856), 1637-1640, 2007 | 884 | 2007 |
| DNA helicases Sgs1 and BLM promote DNA double-strand break resection S Gravel, JR Chapman, C Magill, SP Jackson Genes & development 22 (20), 2767-2772, 2008 | 553 | 2008 |
| RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection JR Chapman, P Barral, JB Vannier, V Borel, M Steger, A Tomas-Loba, ... Molecular cell 49 (5), 858-871, 2013 | 500 | 2013 |
| REV7 counteracts DNA double-strand break resection and affects PARP inhibition G Xu, JR Chapman, I Brandsma, J Yuan, M Mistrik, P Bouwman, ... Nature 521 (7553), 541-544, 2015 | 355 | 2015 |
| Phospho‐dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage JR Chapman, SP Jackson EMBO reports 9 (8), 795-801, 2008 | 297 | 2008 |
| BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair JR Chapman, AJ Sossick, SJ Boulton, SP Jackson Journal of cell science 125 (15), 3529-3534, 2012 | 255 | 2012 |
| Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair FR Day, KS Ruth, DJ Thompson, KL Lunetta, N Pervjakova, DI Chasman, ... Nature genetics 47 (11), 1294-1303, 2015 | 220 | 2015 |
| A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage J Lloyd, JR Chapman, JA Clapperton, LF Haire, E Hartsuiker, J Li, ... Cell 139 (1), 100-111, 2009 | 172 | 2009 |
| Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, ... Molecular cell 45 (4), 505-516, 2012 | 134 | 2012 |
| 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ H Ghezraoui, C Oliveira, JR Becker, K Bilham, D Moralli, C Anzilotti, ... Nature 560 (7716), 122-127, 2018 | 104 | 2018 |
| 53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms R Cuella-Martin, C Oliveira, HE Lockstone, S Snellenberg, N Grolmusova, ... Molecular cell 64 (1), 51-64, 2016 | 79 | 2016 |
| Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility DJ Wright, FR Day, ND Kerrison, F Zink, A Cardona, P Sulem, ... Nature genetics 49 (5), 674, 2017 | 59 | 2017 |
| The CST complex mediates end protection at double-strand breaks and promotes PARP inhibitor sensitivity in BRCA1-deficient cells M Barazas, S Annunziato, SJ Pettitt, I de Krijger, H Ghezraoui, SJ Roobol, ... Cell reports 23 (7), 2107-2118, 2018 | 53 | 2018 |
| Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression K Townsend, H Mason, AN Blackford, ES Miller, JR Chapman, ... Journal of Biological Chemistry 284 (49), 33939-33948, 2009 | 49 | 2009 |
| A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis N Altemose, N Noor, E Bitoun, A Tumian, M Imbeault, JR Chapman, ... Elife 6, e28383, 2017 | 46 | 2017 |
| The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis EM Taylor, SM Cecillon, A Bonis, JR Chapman, LF Povirk, HD Lindsay Nucleic acids research 38 (2), 441-454, 2010 | 44 | 2010 |
| H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids K Nakamura, G Saredi, JR Becker, BM Foster, NV Nguyen, TE Beyer, ... Nature cell biology 21 (3), 311-318, 2019 | 40 | 2019 |
| The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ... Nature communications 9 (1), 1-12, 2018 | 35 | 2018 |
| An essential role for the Zn 2+ transporter ZIP7 in B cell development C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ... Nature immunology 20 (3), 350-361, 2019 | 34 | 2019 |
