Jonathan Ross Chapman
Jonathan Ross Chapman
Principal Investigator, Wellcome Trust Centre for Human Genetics, University of Oxford, UK
Verified email at - Homepage
Cited by
Cited by
Playing the end game: DNA double-strand break repair pathway choice
JR Chapman, MRG Taylor, SJ Boulton
Molecular cell 47 (4), 497-510, 2012
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ...
Science 318 (5856), 1637-1640, 2007
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
S Gravel, JR Chapman, C Magill, SP Jackson
Genes & development 22 (20), 2767-2772, 2008
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection
JR Chapman, P Barral, JB Vannier, V Borel, M Steger, A Tomas-Loba, ...
Molecular cell 49 (5), 858-871, 2013
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
G Xu, JR Chapman, I Brandsma, J Yuan, M Mistrik, P Bouwman, ...
Nature 521 (7553), 541-544, 2015
Phospho‐dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
JR Chapman, SP Jackson
EMBO reports 9 (8), 795-801, 2008
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
JR Chapman, AJ Sossick, SJ Boulton, SP Jackson
Journal of cell science 125 (15), 3529-3534, 2012
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
FR Day, KS Ruth, DJ Thompson, KL Lunetta, N Pervjakova, DI Chasman, ...
Nature genetics 47 (11), 1294-1303, 2015
A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
J Lloyd, JR Chapman, JA Clapperton, LF Haire, E Hartsuiker, J Li, ...
Cell 139 (1), 100-111, 2009
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, ...
Molecular cell 45 (4), 505-516, 2012
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
H Ghezraoui, C Oliveira, JR Becker, K Bilham, D Moralli, C Anzilotti, ...
Nature 560 (7716), 122-127, 2018
53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms
R Cuella-Martin, C Oliveira, HE Lockstone, S Snellenberg, N Grolmusova, ...
Molecular cell 64 (1), 51-64, 2016
Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility
DJ Wright, FR Day, ND Kerrison, F Zink, A Cardona, P Sulem, ...
Nature genetics 49 (5), 674, 2017
The CST complex mediates end protection at double-strand breaks and promotes PARP inhibitor sensitivity in BRCA1-deficient cells
M Barazas, S Annunziato, SJ Pettitt, I de Krijger, H Ghezraoui, SJ Roobol, ...
Cell reports 23 (7), 2107-2118, 2018
Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression
K Townsend, H Mason, AN Blackford, ES Miller, JR Chapman, ...
Journal of Biological Chemistry 284 (49), 33939-33948, 2009
A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
N Altemose, N Noor, E Bitoun, A Tumian, M Imbeault, JR Chapman, ...
Elife 6, e28383, 2017
The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis
EM Taylor, SM Cecillon, A Bonis, JR Chapman, LF Povirk, HD Lindsay
Nucleic acids research 38 (2), 441-454, 2010
H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids
K Nakamura, G Saredi, JR Becker, BM Foster, NV Nguyen, TE Beyer, ...
Nature cell biology 21 (3), 311-318, 2019
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ...
Nature communications 9 (1), 1-12, 2018
An essential role for the Zn 2+ transporter ZIP7 in B cell development
C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ...
Nature immunology 20 (3), 350-361, 2019
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