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Grainne O'Kane
Grainne O'Kane
Princess Margaret Cancer Center
Verifierad e-postadress på tcd.ie
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Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
Cancer discovery 8 (9), 1112-1129, 2018
7912018
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ...
Nature 563 (7732), 579-583, 2018
7072018
Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial
KL Aung, SE Fischer, RE Denroche, GH Jang, A Dodd, S Creighton, ...
Clinical Cancer Research 24 (6), 1344-1354, 2018
4882018
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ...
Nature genetics 52 (2), 231-240, 2020
4462020
EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes
N Marcoux, SN Gettinger, G O’Kane, KC Arbour, JW Neal, H Husain, ...
Journal of Clinical Oncology 37 (4), 278-285, 2019
3472019
GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer
GM O’Kane, BT Grünwald, GH Jang, M Masoomian, S Picardo, RC Grant, ...
Clinical Cancer Research 26 (18), 4901-4910, 2020
2252020
Spatially confined sub-tumor microenvironments in pancreatic cancer
BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ...
Cell 184 (22), 5577-5592. e18, 2021
2232021
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ...
Immunity 55 (2), 324-340. e8, 2022
2152022
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases
AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ...
Cancer cell 35 (2), 267-282. e7, 2019
1732019
Uncommon EGFR mutations in advanced non-small cell lung cancer
GM O’Kane, PA Bradbury, R Feld, NB Leighl, G Liu, KM Pisters, ...
Lung Cancer 109, 137-144, 2017
1532017
Altered gene expression along the glycolysis–cholesterol synthesis axis is associated with outcome in pancreatic cancer
JM Karasinska, JT Topham, SE Kalloger, GH Jang, RE Denroche, ...
Clinical Cancer Research 26 (1), 135-146, 2020
1372020
A phase 2 trial of sunitinib in patients with progressive paraganglioma or pheochromocytoma: the SNIPP trial
GM O’Kane, S Ezzat, AM Joshua, I Bourdeau, R Leibowitz-Amit, HJ Olney, ...
British journal of cancer 120 (12), 1113-1119, 2019
1102019
A four-chemokine signature is associated with a T-cell–inflamed phenotype in primary and metastatic pancreatic cancer
JM Romero, B Grünwald, GH Jang, PP Bavi, A Jhaveri, M Masoomian, ...
Clinical Cancer Research 26 (8), 1997-2010, 2020
1062020
Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome
SN Kalimuthu, GW Wilson, RC Grant, M Seto, G O’Kane, R Vajpeyi, ...
Gut 69 (2), 317-328, 2020
1002020
Genomic features and classification of homologous recombination deficient pancreatic ductal adenocarcinoma
T Golan, GM O’Kane, RE Denroche, M Raitses-Gurevich, RC Grant, ...
Gastroenterology 160 (6), 2119-2132. e9, 2021
992021
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
98
Monitoring and management of immune‐related adverse events associated with programmed cell death protein‐1 axis inhibitors in lung cancer
GM O’Kane, C Labbé, MK Doherty, K Young, H Albaba, NB Leighl
The Oncologist 22 (1), 70-80, 2017
802017
A national stakeholder consensus study of challenges and priorities for clinical learning environments in postgraduate medical education
C Kilty, A Wiese, C Bergin, P Flood, N Fu, M Horgan, A Higgins, B Maher, ...
BMC Medical Education 17, 1-9, 2017
702017
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma
RC Grant, R Denroche, GH Jang, KM Nowak, A Zhang, A Borgida, ...
Gut 70 (10), 1894-1903, 2021
662021
Third-generation tyrosine kinase inhibitors targeting epidermal growth factor receptor mutations in non-small cell lung cancer
TA Barnes, GM O’Kane, MD Vincent, NB Leighl
Frontiers in oncology 7, 113, 2017
642017
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Artiklar 1–20