Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse E Clappier, B Gerby, F Sigaux, M Delord, F Touzri, L Hernandez, ... Journal of Experimental Medicine 208 (4), 653-661, 2011 | 225 | 2011 |
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity F Armstrong, PB de La Grange, B Gerby, MC Rouyez, J Calvo, ... Blood, The Journal of the American Society of Hematology 113 (8), 1730-1740, 2009 | 183 | 2009 |
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ... Cell 150 (3), 575-589, 2012 | 158 | 2012 |
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models C Thiollier, CK Lopez, B Gerby, C Ignacimouttou, S Poglio, Y Duffourd, ... Journal of Experimental Medicine 209 (11), 2017-2031, 2012 | 107 | 2012 |
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia S Kusy, B Gerby, N Goardon, N Gault, F Ferri, D Gérard, F Armstrong, ... Journal of Experimental Medicine 207 (10), 2141-2156, 2010 | 83 | 2010 |
SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells B Gerby, CS Tremblay, M Tremblay, S Rojas-Sutterlin, S Herblot, J Hébert, ... PLoS genetics 10 (12), e1004768, 2014 | 78 | 2014 |
Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations B Gerby, E Clappier, F Armstrong, C Deswarte, J Calvo, S Poglio, ... Leukemia 25 (8), 1249-1258, 2011 | 78 | 2011 |
Piperazinobenzopyranones and phenalkylaminobenzopyranones: potent inhibitors of breast cancer resistance protein (ABCG2) A Boumendjel, E Nicolle, T Moraux, B Gerby, M Blanc, X Ronot, ... Journal of medicinal chemistry 48 (23), 7275-7281, 2005 | 64 | 2005 |
Interleukin‐18 produced by bone marrow‐derived stromal cells supports T‐cell acute leukaemia progression B Uzan, S Poglio, B Gerby, CL Wu, J Gross, F Armstrong, J Calvo, X Cahu, ... EMBO molecular medicine 6 (6), 821-834, 2014 | 43 | 2014 |
High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells B Gerby, DFT Veiga, J Krosl, S Nourreddine, J Ouellette, A Haman, ... The Journal of Clinical Investigation 126 (12), 4569-4584, 2016 | 39 | 2016 |
Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia N Duployez, LA Jamrog, V Fregona, C Hamelle, L Fenwarth, S Lejeune, ... Blood, The Journal of the American Society of Hematology 137 (10), 1424-1428, 2021 | 37 | 2021 |
Genetic interaction between Kit and Scl J Lacombe, G Krosl, M Tremblay, B Gerby, R Martin, PD Aplan, S Lemieux, ... Blood, The Journal of the American Society of Hematology 122 (7), 1150-1161, 2013 | 36 | 2013 |
2-Arylidenedihydroindole-3-ones: Design, synthesis, and biological activity on bladder carcinoma cell lines B Gerby, A Boumendjel, M Blanc, PP Bringuier, P Champelovier, ... Bioorganic & Medicinal Chemistry Letters 17 (1), 208-213, 2007 | 33 | 2007 |
PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice L Jamrog, G Chemin, V Fregona, L Coster, M Pasquet, C Oudinet, ... Proceedings of the National Academy of Sciences 115 (41), 10357-10362, 2018 | 30 | 2018 |
Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity B Gerby, F Armstrong, PB de la Grange, H Medyouf, J Calvo, ... Leukemia 24 (3), 646-649, 2010 | 16 | 2010 |
Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ... Cell 150 (3), 575, 2012 | 12 | 2012 |
PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation C Cresson, S Péron, L Jamrog, N Rouquié, N Prade, M Dubois, ... Oncotarget 9 (67), 32841, 2018 | 8 | 2018 |
The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11 M Lafage-Pochitaloff, B Gerby, V Baccini, L Largeaud, V Fregona, ... Blood Advances 6 (2), 386-398, 2022 | 7 | 2022 |
Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance R Barattin, B Gerby, K Bourges, G Hardy, J Olivares, J Boutonnat, ... Anticancer research 30 (7), 2553-2559, 2010 | 7 | 2010 |
Oncogene-induced reprogramming in acute lymphoblastic leukemia: towards targeted therapy of leukemia-initiating cells V Fregona, M Bayet, B Gerby Cancers 13 (21), 5511, 2021 | 6 | 2021 |