Eleonora Gianti
Title
Cited by
Cited by
Year
Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 …
Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ...
Journal of the American Chemical Society 136 (52), 17987-17995, 2014
592014
Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors
F Thaler, A Colombo, A Mai, R Amici, C Bigogno, R Boggio, A Cappa, ...
Journal of Medicinal Chemistry 53 (2), 822-839, 2009
312009
Identification and selection of “privileged fragments” suitable for primary screening
E Gianti, L Sartori
Journal of Chemical Information and Modeling 48 (11), 2129-2139, 2008
242008
Hydrogen-bonded water molecules in the M2 channel of the influenza A virus guide the binding preferences of ammonium-based inhibitors
E Gianti, V Carnevale, WF DeGrado, ML Klein, G Fiorin
The Journal of Physical Chemistry B 119 (3), 1173-1183, 2015
222015
Does Proton Conduction in the Voltage-Gated H+ Channel hHv1 Involve Grotthuss-Like Hopping via Acidic Residues?
S van Keulen, E Gianti, V Carnevale, M Klein, U Rothlisberger, ...
J Phys Chem B, DOI:10.1021/acs.jpcb.6b08339, 2016
172016
Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling
GR Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG
Biophys J, DOI:10.1016/j.bpj.2017.08.040, 2017
16*2017
Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design
E Gianti, TE Messick, PM Lieberman, RJ Zauhar
Journal of computer-aided molecular design 30 (4), 285-303, 2016
162016
Modeling androgen receptor flexibility: a binding mode hypothesis of CYP17 inhibitors/antiandrogens for prostate cancer therapy
E Gianti, RJ Zauhar
Journal of chemical information and modeling 52 (10), 2670-2683, 2012
152012
On the role of water density fluctuations in the inhibition of a proton channel
E Gianti, L Delemotte, ML Klein, V Carnevale
Proceedings of the National Academy of Sciences 113 (52), E8359-E8368, 2016
132016
Fragment-based Shape Signatures: a new tool for virtual screening and drug discovery
RJ Zauhar, E Gianti, WJ Welsh
Journal of Computer-Aided Molecular Design 27 (12), 1009-1036, 2013
132013
An SH2 domain model of STAT5 in complex with phospho-peptides define “STAT5 Binding Signatures”
E Gianti, RJ Zauhar
Journal of computer-aided molecular design 29 (5), 451-470, 2015
92015
PoInTree: a polar and interactive phylogenetic tree.
M Carreras, E Gianti, L Sartori, SE Plyte, A Isacchi, R Bosotti
Genomics Proteomics Bioinformatics 3 (1), 58-60, 2005
3*2005
TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism
T Chernov-Rogan, E Gianti, C Liu, E Villemure, AP Cridland, X Hu, ...
Proceedings of the National Academy of Sciences 116 (51), 26008-26019, 2019
22019
Suppression of Zika virus infection in the brain by the antiretroviral drug rilpivirine
IK Sariyer, J Gordon, TH Burdo, HS Wollebo, E Gianti, M Donadoni, ...
Molecular Therapy 27 (12), 2067-2079, 2019
12019
Computational approaches to studying voltage-gated ion channel modulation by general anesthetics
E Gianti, V Carnevale
Methods in enzymology 602, 25-59, 2018
12018
The Molecular Mechanisms of TRMP3 Channel Regulation by Gβγ and Phosphoinositides
S Zhao, E Gianti, V Carnevale, T Rohacs
Biophysical Journal 118 (3), 21a, 2020
2020
Mechanism of TRPV1 Activation by Oxytocin
A Suma, E Gianti, Y Nersesyan, E Zakharian, V Carnevale
Biophysical Journal 118 (3), 412a, 2020
2020
Dual Regulation of TRPV1 by Phosphatidylinositol via Functionally Distinct Binding Sites
AT Yazici, E Gianti, V Carnevale, T Rohacs
Biophysical Journal 118 (3), 411a, 2020
2020
TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism (vol 116, pg 26008, 2019)
T Chernov-Rogan, E Gianti, C Liu, E Villemure, AP Cridland, X Hu, ...
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2020
2020
Activation of TRPV1 by Lipids: Can Lipid Tails Bridge the Gap between the Vanilloid Binding Site and the Peripheral Cavities?
E Gianti, ML Klein, T Rohacs, V Carnevale
Biophysical Journal 116 (3), 536a, 2019
2019
The system can't perform the operation now. Try again later.
Articles 1–20