Inhibition of the fungal fatty acid synthase type I multienzyme complex P Johansson, B Wiltschi, P Kumari, B Kessler, C Vonrhein, J Vonck, ... Proceedings of the National Academy of Sciences 105 (35), 12803-12808, 2008 | 103 | 2008 |
Parameters affecting the X-ray dose absorbed by macromolecular crystals JW Murray, E Rudino-Pinera, RL Owen, M Grininger, RBG Ravelli, ... Journal of synchrotron radiation 12 (3), 268-275, 2005 | 83 | 2005 |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production J Gajewski, R Pavlovic, M Fischer, E Boles, M Grininger Nature communications 8 (1), 1-8, 2017 | 79 | 2017 |
Expanding the product portfolio of fungal type I fatty acid synthases Z Zhu, YJ Zhou, A Krivoruchko, M Grininger, ZK Zhao, J Nielsen Nature chemical biology 13 (4), 360-362, 2017 | 72 | 2017 |
Protein denaturation at the air-water interface and how to prevent it E D'Imprima, D Floris, M Joppe, R Sánchez, M Grininger, W Kühlbrandt Elife 8, e42747, 2019 | 68 | 2019 |
Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy P Gipson, DJ Mills, R Wouts, M Grininger, J Vonck, W Kühlbrandt Proceedings of the National Academy of Sciences 107 (20), 9164-9169, 2010 | 58 | 2010 |
Engineering strategies for rational polyketide synthase design M Klaus, M Grininger Natural product reports 35 (10), 1070-1081, 2018 | 55 | 2018 |
Dodecins: a family of lumichrome binding proteins M Grininger, K Zeth, D Oesterhelt Journal of molecular biology 357 (3), 842-857, 2006 | 53 | 2006 |
Engineering fatty acid synthases for directed polyketide production J Gajewski, F Buelens, S Serdjukow, M Janßen, N Cortina, H Grubmüller, ... Nature chemical biology 13 (4), 363-365, 2017 | 50 | 2017 |
Dodecin is the key player in flavin homeostasis of archaea M Grininger, H Staudt, P Johansson, J Wachtveitl, D Oesterhelt Journal of Biological Chemistry 284 (19), 13068-13076, 2009 | 46 | 2009 |
Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems M Grininger Current opinion in structural biology 25, 49-56, 2014 | 43 | 2014 |
Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase P Johansson, B Mulinacci, C Koestler, R Vollrath, D Oesterhelt, ... Structure 17 (8), 1063-1074, 2009 | 43 | 2009 |
Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase A Wende, P Johansson, R Vollrath, M Dyall-Smith, D Oesterhelt, ... Journal of molecular biology 400 (1), 52-62, 2010 | 34 | 2010 |
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex L Ciccarelli, SR Connell, M Enderle, DJ Mills, J Vonck, M Grininger Structure 21 (7), 1251-1257, 2013 | 30 | 2013 |
Dodecin sequesters FAD in closed conformation from the aqueous solution M Grininger, F Seiler, K Zeth, D Oesterhelt Journal of molecular biology 364 (4), 561-566, 2006 | 29 | 2006 |
Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase C Anselmi, M Grininger, P Gipson, JD Faraldo-Gómez Journal of the American Chemical Society 132 (35), 12357-12364, 2010 | 28 | 2010 |
Fatty acid biosynthesis: Chain‐length regulation and control CS Heil, SS Wehrheim, KS Paithankar, M Grininger ChemBioChem 20 (18), 2298-2321, 2019 | 24 | 2019 |
Ultrafast excited-state deactivation of flavins bound to dodecin H Staudt, D Oesterhelt, M Grininger, J Wachtveitl Journal of Biological Chemistry 287 (21), 17637-17644, 2012 | 24 | 2012 |
Cryo‐EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS M Fischer, D Rhinow, Z Zhu, DJ Mills, ZK Zhao, J Vonck, M Grininger Protein Science 24 (6), 987-995, 2015 | 22 | 2015 |
Multi-ligand-binding flavoprotein dodecin as a key element for reversible surface modification in nano-biotechnology C Gutiérrez Sánchez, Q Su, H Schönherr, M Grininger, G Nöll ACS nano 9 (4), 3491-3500, 2015 | 19 | 2015 |