Deniz Kirik
Deniz Kirik
Professor of Neuroscience
Verified email at
Cited by
Cited by
Neuronal replacement from endogenous precursors in the adult brain after stroke
A Arvidsson, T Collin, D Kirik, Z Kokaia, O Lindvall
Nature medicine 8 (9), 963-970, 2002
Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system
D Kirik, C Rosenblad, C Burger, C Lundberg, TE Johansen, N Muzyczka, ...
Journal of Neuroscience 22 (7), 2780-2791, 2002
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
D Kirik, C Rosenblad, A Björklund
Experimental neurology 152 (2), 259-277, 1998
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
M Lundblad, M Andersson, C Winkler, D Kirik, N Wierup, MA Cenci
European Journal of Neuroscience 15 (1), 120-132, 2002
Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats
M Carta, T Carlsson, D Kirik, A Björklund
Brain 130 (7), 1819-1833, 2007
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned …
D Kirik, C Rosenblad, A Björklund, RJ Mandel
Journal of Neuroscience 20 (12), 4686-4700, 2000
L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function
C Winkler, D Kirik, A Björklund, MA Cenci
Neurobiology of disease 10 (2), 165-186, 2002
Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: a new primate model of Parkinson's disease
D Kirik, LE Annett, C Burger, N Muzyczka, RJ Mandel, A Björklund
Proceedings of the National Academy of Sciences 100 (5), 2884-2889, 2003
Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat …
A Björklund, D Kirik, C Rosenblad, B Georgievska, C Lundberg, ...
Brain research 886 (1-2), 82-98, 2000
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
BA Horger, MC Nishimura, MP Armanini, LC Wang, KT Poulsen, ...
Journal of Neuroscience 18 (13), 4929-4937, 1998
A general chemical method to regulate protein stability in the mammalian central nervous system
M Iwamoto, T Björklund, C Lundberg, D Kirik, TJ Wandless
Chemistry & biology 17 (9), 981-988, 2010
Localized striatal delivery of GDNF as a treatment for Parkinson disease
D Kirik, B Georgievska, A Björklund
Nature neuroscience 7 (2), 105-110, 2004
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
A Björklund, C Rosenblad, C Winkler, D Kirik
Neurobiology of disease 4 (3-4), 186-200, 1997
Cell transplantation in Parkinson's disease: how can we make it work?
C Winkler, D Kirik, A Björklund
Trends in neurosciences 28 (2), 86-92, 2005
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the …
C Rosenblad, D Kirik, B Devaux, B Moffat, HS Phillips, A Björklund
European Journal of Neuroscience 11 (5), 1554-1566, 1999
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of l-DOPA-induced dyskinesia
A Munoz, Q Li, F Gardoni, E Marcello, C Qin, T Carlsson, D Kirik, ...
Brain 131 (12), 3380-3394, 2008
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and …
L Thompson, P Barraud, E Andersson, D Kirik, A Björklund
Journal of Neuroscience 25 (27), 6467-6477, 2005
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral …
A Eslamboli, B Georgievska, RM Ridley, HF Baker, N Muzyczka, C Burger, ...
Journal of Neuroscience 25 (4), 769-777, 2005
Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease
H Hall, S Reyes, N Landeck, C Bye, G Leanza, K Double, L Thompson, ...
Brain 137 (9), 2493-2508, 2014
Microglia acquire distinct activation profiles depending on the degree of α-synuclein neuropathology in a rAAV based model of Parkinson's disease
V Sanchez-Guajardo, F Febbraro, D Kirik, M Romero-Ramos
PloS one 5 (1), e8784, 2010
The system can't perform the operation now. Try again later.
Articles 1–20