Alexander Pietras

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Erik FredlundDept. Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, SwedenVerified email at ki.se
Vasiliki PantazopoulouPostdoctoral Fellow, Salk InstituteVerified email at salk.edu
Eric HollandFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
Elisa Stellaria GrassiTraslational Cancer Research, University of LundVerified email at unimi.it
Jonas SjölundTranslational Cancer Research, Lund UniversityVerified email at med.lu.se
David GisselssonProfessor of Molecular Pathology, Lund UniversityVerified email at med.lu.se
Kristoffer von StedingkPost Doc | Translational Cancer Research | Lund UniversityVerified email at med.lu.se
Johan Vallon-ChristerssonDivision of Oncology, Department of Clinical Sciences Lund, Lund University, SwedenVerified email at med.lu.se
Åke BorgDepartment of Oncology, Clinical Sciences, Lund University, SwedenVerified email at med.lu.se
Katarina GradinKarolinska InstitutetVerified email at ki.se
David LindgrenCenter for Molecular Pathology, Lund University, SwedenVerified email at med.lu.se
Kenneth PitterAssistant Professor in the Department of Radiation Oncology, The Ohio State Comprehensive CancerVerified email at osumc.edu
Nduka AmankulorUniversity of PennsylvaniaVerified email at pennmedicine.upenn.edu
David R. KaplanHospital for Sick ChildrenVerified email at sickkids.ca
Mattias BeltingProfessor/Senior Consultant of Oncology, Lund University, Lund, Sweden.Verified email at med.lu.se
Massimo SquatritoCentro Nacional de Investigaciones Oncológicas (CNIO)Verified email at cnio.es
Johan BengzonConsultant, Dept of Neurosurgery, Lund University HospitalVerified email at med.lu.se
Fredrik Johansson SwartlingUppsala UniversityVerified email at igp.uu.se
Joseph DoughertyProfessor, Washington UniversityVerified email at genetics.wustl.edu
Cameron BrennanAttending Neurosurgeon, Memorial Sloan-Kettering Cancer CenterVerified email at mskcc.org

Alexander Pietras

Lund University | Translational Cancer Research

Verified email at med.lu.se - Homepage

cancer biology neuro-oncology brain tumors hypoxia


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Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ... Cancer cell 10 (5), 413-423, 2006	848	2006
Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth A Pietras, AM Katz, EJ Ekström, B Wee, JJ Halliday, KL Pitter, JL Werbeck, ... Cell stem cell 14 (3), 357-369, 2014	503	2014
Hypoxia inducible factor-2alpha in cancer T Lofstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ... CELL CYCLE-LANDES BIOSCIENCE- 6 (8), 919, 2007	239	2007
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Sjölund, M Johansson, S Manna, C Norin, A Pietras, S Beckman, ... The Journal of clinical investigation 118 (1), 217-228, 2008	217	2008
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ... Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009	169	2009
High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche A Pietras, D Gisselsson, I Øra, R Noguera, S Beckman, S Navarro, ... The Journal of pathology 214 (4), 482-488, 2008	137	2008
Cancer stem cells in tumor heterogeneity A Pietras Advances in cancer research 112, 255-281, 2011	107	2011
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization R Noguera, E Fredlund, M Piqueras, A Pietras, S Beckman, S Navarro, ... Clinical Cancer Research 15 (23), 7130-7136, 2009	98	2009
CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells E Johansson, ES Grassi, V Pantazopoulou, B Tong, D Lindgren, TJ Berg, ... Cell reports 20 (7), 1641-1653, 2017	96	2017
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression EI Fomchenko, JD Dougherty, KY Helmy, AM Katz, A Pietras, C Brennan, ... PloS one 6 (7), e20605, 2011	93	2011
The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization A Pietras, AS Johnsson, S Påhlman Diverse Effects of Hypoxia on Tumor Progression, 1-20, 2010	79	2010
JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation A Pietras, K von Stedingk, D Lindgren, S Påhlman, H Axelson Molecular Cancer Research 9 (5), 626, 2011	74	2011
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells HM Pettersson, A Pietras, M Munksgaard Persson, J Karlsson, ... Molecular cancer therapeutics 8 (1), 160-170, 2009	60	2009
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells B Wee, A Pietras, T Ozawa, E Bazzoli, O Podlaha, C Antczak, ... Scientific reports 6 (1), 25956, 2016	56	2016
Arsenic trioxide and neuroblastoma cytotoxicity HM Pettersson, J Karlsson, A Pietras, I Øra, S Påhlman Journal of bioenergetics and biomembranes 39 (1), 35-41, 2007	34	2007
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma ES Grassi, V Pantazopoulou, A Pietras Oncogene 39 (20), 4028-4044, 2020	28	2020
The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2 TJ Berg, C Marques, V Pantazopoulou, E Johansson, K Von Stedingk, ... Cancer research 81 (8), 2101-2115, 2021	26	2021
Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells TJ Berg, A Pietras Seminars in Cancer Biology 86, 846-856, 2022	22	2022
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax J Karlsson, A Pietras, S Beckman, HM Pettersson, C Larsson, S Påhlman Oncogene 26 (42), 6150-6159, 2007	22	2007
The p75 neurotrophin receptor enhances HIF-dependent signaling in glioma B Tong, V Pantazopoulou, E Johansson, A Pietras Experimental cell research 371 (1), 122-129, 2018	16	2018

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