Alexander Pietras

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Erik FredlundDept. Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, SwedenVerified email at ki.se
Vasiliki PantazopoulouPhD, Lund UniversityVerified email at med.lu.se
Eric HollandFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
David GisselssonProfessor of Molecular Pathology, Lund UniversityVerified email at med.lu.se
Jonas SjölundTranslational Cancer Research, Lund UniversityVerified email at med.lu.se
Elisa Stellaria GrassiTraslational Cancer Research, University of LundVerified email at unimi.it
Kristoffer von StedingkPost Doc | Translational Cancer Research | Lund UniversityVerified email at med.lu.se
Johan Vallon-ChristerssonDivision of Oncology, Department of Clinical Sciences Lund, Lund University, SwedenVerified email at med.lu.se
Åke BorgDepartment of Oncology, Clinical Sciences, Lund University, SwedenVerified email at med.lu.se
Katarina GradinKarolinska InstitutetVerified email at ki.se
David LindgrenCenter for Molecular Pathology, Lund University, SwedenVerified email at med.lu.se
Kenneth PitterAssistant Professor in the Department of Radiation Oncology, The Ohio State Comprehensive CancerVerified email at osumc.edu
David R. KaplanHospital for Sick ChildrenVerified email at sickkids.ca
Joseph DoughertyProfessor, Washington UniversityVerified email at genetics.wustl.edu
Cameron BrennanAttending Neurosurgeon, Memorial Sloan-Kettering Cancer CenterVerified email at mskcc.org
Ana MilosevicThe Rockefeller UniversityVerified email at rockefeller.edu
Mattias BeltingProfessor/Senior Consultant of Oncology, Lund University, Lund, Sweden. Guest Professor in ClinicalVerified email at med.lu.se
Massimo SquatritoCentro Nacional de Investigaciones Oncológicas (CNIO)Verified email at cnio.es
Johan BengzonConsultant, Dept of Neurosurgery, Lund University HospitalVerified email at med.lu.se
Franziska MichorAssociate Professor of Biostatistics, Harvard UniversityVerified email at jimmy.harvard.edu

Alexander Pietras

Lund University | Translational Cancer Research

Verified email at med.lu.se - Homepage

cancer biology neuro-oncology brain tumors hypoxia


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Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ... Cancer cell 10 (5), 413-423, 2006	806	2006
Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth A Pietras, AM Katz, EJ Ekström, B Wee, JJ Halliday, KL Pitter, JL Werbeck, ... Cell stem cell 14 (3), 357-369, 2014	465	2014
Hypoxia inducible factor-2alpha in cancer T Lofstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ... CELL CYCLE-LANDES BIOSCIENCE- 6 (8), 919, 2007	232	2007
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Sjölund, M Johansson, S Manna, C Norin, A Pietras, S Beckman, ... The Journal of clinical investigation 118 (1), 217-228, 2008	212	2008
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ... Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009	167	2009
High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche A Pietras, D Gisselsson, I Øra, R Noguera, S Beckman, S Navarro, ... The Journal of pathology 214 (4), 482-488, 2008	130	2008
Cancer stem cells in tumor heterogeneity A Pietras Advances in cancer research 112, 255-281, 2011	104	2011
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor VascularizationHIFs, VEGF, and … R Noguera, E Fredlund, M Piqueras, A Pietras, S Beckman, S Navarro, ... Clinical Cancer Research 15 (23), 7130-7136, 2009	94	2009
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression EI Fomchenko, JD Dougherty, KY Helmy, AM Katz, A Pietras, C Brennan, ... PloS one 6 (7), e20605, 2011	90	2011
CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells E Johansson, ES Grassi, V Pantazopoulou, B Tong, D Lindgren, TJ Berg, ... Cell reports 20 (7), 1641-1653, 2017	86	2017
The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization A Pietras, AS Johnsson, S Påhlman Diverse Effects of Hypoxia on Tumor Progression, 1-20, 2010	78	2010
JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation A Pietras, K von Stedingk, D Lindgren, S Påhlman, H Axelson Molecular Cancer Research 9 (5), 626, 2011	69	2011
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells HM Pettersson, A Pietras, M Munksgaard Persson, J Karlsson, ... Molecular cancer therapeutics 8 (1), 160-170, 2009	59	2009
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells B Wee, A Pietras, T Ozawa, E Bazzoli, O Podlaha, C Antczak, ... Scientific reports 6 (1), 1-9, 2016	51	2016
Arsenic trioxide and neuroblastoma cytotoxicity HM Pettersson, J Karlsson, A Pietras, I Øra, S Påhlman Journal of bioenergetics and biomembranes 39 (1), 35-41, 2007	32	2007
The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2RT-Induced Microenvironmental Support of Radioresistance TJ Berg, C Marques, V Pantazopoulou, E Johansson, K Von Stedingk, ... Cancer research 81 (8), 2101-2115, 2021	21	2021
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma ES Grassi, V Pantazopoulou, A Pietras Oncogene 39 (20), 4028-4044, 2020	21	2020
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax J Karlsson, A Pietras, S Beckman, HM Pettersson, C Larsson, S Påhlman Oncogene 26 (42), 6150-6159, 2007	20	2007
The p75 neurotrophin receptor enhances HIF-dependent signaling in glioma B Tong, V Pantazopoulou, E Johansson, A Pietras Experimental cell research 371 (1), 122-129, 2018	16	2018
Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells TJ Berg, A Pietras Seminars in cancer biology, 2022	11	2022

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