Alexander Pietras

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Erik FredlundDept. Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, SwedenVerified email at ki.se
Vasiliki PantazopoulouPostdoctoral Fellow, Salk InstituteVerified email at salk.edu
Jonas SjölundTranslational Cancer Research, Lund UniversityVerified email at med.lu.se
Eric HollandFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
Elisa Stellaria GrassiTraslational Cancer Research, University of LundVerified email at unimi.it
David GisselssonProfessor of Molecular Pathology, Lund UniversityVerified email at med.lu.se
Jason T HuseProfessor, Department of Pathology, University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Kristoffer von StedingkPost Doc | Translational Cancer Research | Lund UniversityVerified email at med.lu.se
Johan Vallon-ChristerssonDivision of Oncology, Department of Clinical Sciences Lund, Lund University, SwedenVerified email at med.lu.se
Åke BorgDepartment of Oncology, Clinical Sciences, Lund University, SwedenVerified email at med.lu.se
Katarina GradinKarolinska InstitutetVerified email at ki.se
David LindgrenCenter for Molecular Pathology, Lund University, SwedenVerified email at med.lu.se
Kenneth PitterAssistant Professor in the Department of Radiation Oncology, The Ohio State Comprehensive CancerVerified email at osumc.edu
Nduka AmankulorUniversity of PennsylvaniaVerified email at pennmedicine.upenn.edu
Mattias BeltingProfessor/Senior Consultant of Oncology, Lund University, Lund, Sweden.Verified email at med.lu.se
David R. KaplanHospital for Sick ChildrenVerified email at sickkids.ca
Massimo SquatritoCentro Nacional de Investigaciones Oncológicas (CNIO)Verified email at cnio.es
Johan BengzonConsultant, Dept of Neurosurgery, Lund University HospitalVerified email at med.lu.se
Fredrik SwartlingAssoc. Professor, Uppsala UniversityVerified email at igp.uu.se
Joseph DoughertyProfessor, Washington UniversityVerified email at genetics.wustl.edu

Alexander Pietras

Lund University | Translational Cancer Research

Verified email at med.lu.se - Homepage

cancer biology neuro-oncology brain tumors hypoxia


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Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ... Cancer cell 10 (5), 413-423, 2006	885	2006
Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth A Pietras, AM Katz, EJ Ekström, B Wee, JJ Halliday, KL Pitter, JL Werbeck, ... Cell stem cell 14 (3), 357-369, 2014	535	2014
Hypoxia inducible factor-2alpha in cancer T Lofstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ... CELL CYCLE-LANDES BIOSCIENCE- 6 (8), 919, 2007	246	2007
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Sjölund, M Johansson, S Manna, C Norin, A Pietras, S Beckman, ... The Journal of clinical investigation 118 (1), 217-228, 2008	220	2008
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ... Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009	173	2009
High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche A Pietras, D Gisselsson, I Øra, R Noguera, S Beckman, S Navarro, ... The Journal of pathology 214 (4), 482-488, 2008	142	2008
Cancer stem cells in tumor heterogeneity A Pietras Advances in cancer research 112, 255-281, 2011	114	2011
CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells E Johansson, ES Grassi, V Pantazopoulou, B Tong, D Lindgren, TJ Berg, ... Cell reports 20 (7), 1641-1653, 2017	110	2017
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization R Noguera, E Fredlund, M Piqueras, A Pietras, S Beckman, S Navarro, ... Clinical cancer research 15 (23), 7130-7136, 2009	101	2009
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression EI Fomchenko, JD Dougherty, KY Helmy, AM Katz, A Pietras, C Brennan, ... PloS one 6 (7), e20605, 2011	95	2011
The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization A Pietras, AS Johnsson, S Påhlman Diverse Effects of Hypoxia on Tumor Progression, 1-20, 2010	79	2010
JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation A Pietras, K von Stedingk, D Lindgren, S Påhlman, H Axelson Molecular Cancer Research 9 (5), 626, 2011	75	2011
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells B Wee, A Pietras, T Ozawa, E Bazzoli, O Podlaha, C Antczak, ... Scientific reports 6 (1), 25956, 2016	62	2016
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells HM Pettersson, A Pietras, M Munksgaard Persson, J Karlsson, ... Molecular cancer therapeutics 8 (1), 160-170, 2009	60	2009
Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells TJ Berg, A Pietras Seminars in cancer biology 86, 846-856, 2022	41	2022
The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2 TJ Berg, C Marques, V Pantazopoulou, E Johansson, K Von Stedingk, ... Cancer research 81 (8), 2101-2115, 2021	35	2021
Arsenic trioxide and neuroblastoma cytotoxicity HM Pettersson, J Karlsson, A Pietras, I Øra, S Påhlman Journal of bioenergetics and biomembranes 39 (1), 35-41, 2007	34	2007
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma ES Grassi, V Pantazopoulou, A Pietras Oncogene 39 (20), 4028-4044, 2020	31	2020
Emerging roles of DLK1 in the stem cell niche and cancer stemness ES Grassi, A Pietras Journal of Histochemistry & Cytochemistry 70 (1), 17-28, 2022	24	2022
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax J Karlsson, A Pietras, S Beckman, HM Pettersson, C Larsson, S Påhlman Oncogene 26 (42), 6150-6159, 2007	22	2007

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