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David Ruau
David Ruau
CSO @ Sensyne Health
Verified email at cam.ac.uk - Homepage
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Year
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
JB Kim, H Zaehres, G Wu, L Gentile, K Ko, V Sebastiano, ...
nature 454 (7204), 646-650, 2008
12992008
Oct4-induced pluripotency in adult neural stem cells
JB Kim, V Sebastiano, G Wu, MJ Araúzo-Bravo, P Sasse, L Gentile, K Ko, ...
cell 136 (3), 411-419, 2009
12342009
Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage
Y Pan, A Leifert, D Ruau, S Neuss, J Bornemann, G Schmid, W Brandau, ...
small 5 (18), 2067-2076, 2009
8342009
Induction of pluripotency in adult unipotent germline stem cells
K Ko, N Tapia, G Wu, JB Kim, MJA Bravo, P Sasse, T Glaser, D Ruau, ...
Cell stem cell 5 (1), 87-96, 2009
2992009
Sex differences in reported pain across 11,000 patients captured in electronic medical records
D Ruau, LY Liu, JD Clark, MS Angst, AJ Butte
The Journal of Pain 13 (3), 228-234, 2012
2192012
DNMT3A loss drives enhancer hypomethylation in FLT3-ITD-associated leukemias
L Yang, B Rodriguez, A Mayle, HJ Park, X Lin, M Luo, M Jeong, CV Curry, ...
Cancer cell 29 (6), 922-934, 2016
1312016
Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases
R Chen, E Corona, M Sikora, JT Dudley, AA Morgan, A Moreno-Estrada, ...
PLoS genetics 8 (4), e1002621, 2012
1222012
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors
F Meier-Stiegen, R Schwanbeck, K Bernoth, S Martini, T Hieronymus, ...
PloS one 5 (7), e11481, 2010
1192010
CODEX: a next-generation sequencing experiment database for the haematopoietic and embryonic stem cell communities
M Sánchez-Castillo, D Ruau, AC Wilkinson, FSL Ng, R Hannah, ...
Nucleic acids research 43 (D1), D1117-D1123, 2015
1092015
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells
D Ruau, R Ensenat-Waser, TC Dinger, DS Vallabhapurapu, ...
Stem cells 26 (4), 920-926, 2008
1052008
The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia
G Giotopoulos, WI Chan, SJ Horton, D Ruau, P Gallipoli, A Fowler, ...
Oncogene 35 (3), 279-289, 2016
662016
Disease risk factors identified through shared genetic architecture and electronic medical records
L Li, DJ Ruau, CJ Patel, SC Weber, R Chen, NP Tatonetti, JT Dudley, ...
Science translational medicine 6 (234), 234ra57-234ra57, 2014
522014
Neural induction intermediates exhibit distinct roles of Fgf signaling
J Sterneckert, M Stehling, C Bernemann, MJ Araúzo-Bravo, B Greber, ...
Stem cells 28 (10), 1772-1781, 2010
412010
Update of NUREBASE: nuclear hormone receptor functional genomics
D Ruau, J Duarte, T Ourjdal, G Perrière, V Laudet, M Robinson‐Rechavi
Nucleic acids research 32 (suppl_1), D165-D167, 2004
342004
Transforming growth factor β1 up‐regulates interferon regulatory factor 8 during dendritic cell development
XS Ju, D Ruau, P Jäntti, K Seré, C Becker, E Wiercinska, C Bartz, ...
European journal of immunology 37 (5), 1174-1183, 2007
272007
Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells
FSL Ng, J Schütte, D Ruau, E Diamanti, R Hannah, SJ Kinston, ...
Nucleic acids research 42 (22), 13513-13524, 2014
182014
GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells
I Gamper, KR Koh, D Ruau, K Ullrich, J Bartunkova, D Piroth, C Hacker, ...
Experimental hematology 37 (5), 539-548. e4, 2009
182009
Integrative approach to pain genetics identifies pain sensitivity loci across diseases
D Ruau, JT Dudley, R Chen, NG Phillips, GE Swan, LC Lazzeroni, ...
PLoS computational biology 8 (6), e1002538, 2012
172012
Comparison of Automated and Human Assignment of MeSH Terms on Publicly-Available Molecular Datasets
D Ruau, M Mbagwu, JT Dudley, V Krishnan, AJ Butte
Journal of Biomedical Informatics, 2011
172011
Systematic identification of risk factors for Alzheimer's disease through shared genetic architecture and electronic medical records
L Li, D Ruau, R Chen, S Weber, AJ Butte
Biocomputing 2013, 224-235, 2013
152013
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