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Klaus Reuter
Klaus Reuter
Institut für Pharmazeutische Chemie - Uni Marburg
Verifierad e-postadress på staff.uni-marburg.de
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Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4′-phosphopantetheinyl transferase superfamily
K Reuter, MR Mofid, MA Marahiel, R Ficner
The EMBO journal 18 (23), 6823-6831, 1999
2641999
Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis
K Reuter, S Sanderbrand, H Jomaa, J Wiesner, I Steinbrecher, E Beck, ...
Journal of Biological Chemistry 277 (7), 5378-5384, 2002
1872002
Crystal structure of tRNA‐guanine transglycosylase: RNA modification by base exchange.
C Romier, K Reuter, D Suck, R Ficner
The EMBO journal 15 (11), 2850-2857, 1996
1601996
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis
R Brenk, L Naerum, U Grädler, HD Gerber, GA Garcia, K Reuter, ...
Journal of medicinal chemistry 46 (7), 1133-1143, 2003
1282003
The crystal structure of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain …
C Grimm, E Maser, E Möbus, G Klebe, K Reuter, R Ficner
Journal of Biological Chemistry 275 (52), 41333-41339, 2000
1162000
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase
U Grädler, HD Gerber, DAM Goodenough-Lashua, GA Garcia, R Ficner, ...
Journal of Molecular Biology 306 (3), 455-467, 2001
1042001
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes
K Reuter, R Slany, F Ullrich, H Kersten
Journal of bacteriology 173 (7), 2256-2264, 1991
981991
Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein
K Reuter, S Nottrott, P Fabrizio, R Lührmann, R Ficner
Journal of molecular biology 294 (2), 515-525, 1999
971999
Mechanism and Substrate Specificity of tRNA–Guanine Transglycosylases (TGTs): tRNA‐Modifying Enzymes from the Three Different Kingdoms of Life Share a Common Catalytic Mechanism
B Stengl, K Reuter, G Klebe
ChemBioChem 6 (11), 1926-1939, 2005
952005
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron (II) and 2-oxoglutarate-dependent dioxygenase EctD
K Reuter, M Pittelkow, J Bursy, A Heine, T Craan, E Bremer
PloS one 5 (5), e10647, 2010
832010
Mutagenesis and Crystallographic Studies of Zymomonas mobilis tRNA-Guanine Transglycosylase Reveal Aspartate 102 as the Active Site Nucleophile,
C Romier, K Reuter, D Suck, R Ficner
Biochemistry 35 (49), 15734-15739, 1996
641996
Sequence analysis and overexpression of the Zymomonas mobilis tgt gene encoding tRNA-guanine transglycosylase: purification and biochemical characterization of the enzyme
K Reuter, R Ficner
Journal of bacteriology 177 (18), 5284-5288, 1995
571995
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction
T Ritschel, C Atmanene, K Reuter, A Van Dorsselaer, ...
Journal of molecular biology 393 (4), 833-847, 2009
562009
A novel recessive hyperekplexia allele GLRA1 (S231R): genotyping by MALDI-TOF mass spectrometry and functional characterisation as a determinant of cellular glycine receptor …
A Humeny, T Bonk, K Becker, M Jafari-Boroujerdi, U Stephani, K Reuter, ...
European Journal of Human Genetics 10 (3), 188-196, 2002
552002
Flexible Adaptations in the Structure of the tRNA‐Modifying Enzyme tRNA–Guanine Transglycosylase and Their Implications for Substrate Selectivity, Reaction Mechanism and …
R Brenk, MT Stubbs, A Heine, K Reuter, G Klebe
ChemBioChem 4 (10), 1066-1077, 2003
492003
3α-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance, three-dimensional structure and gene regulation
E Maser, G Xiong, C Grimm, R Ficner, K Reuter
Chemico-Biological Interactions 130, 707-722, 2001
492001
Purification, crystallization, and preliminary X‐ray diffraction studies of tRNA‐guanine transglycosylase from Zymomonas mobilis
C Romier, R Ficner, K Reuter, D Suck
Proteins: Structure, Function, and Bioinformatics 24 (4), 516-519, 1996
491996
Synthesis, Biological Evaluation, and Crystallographic Studies of Extended Guanine‐Based (lin‐Benzoguanine) Inhibitors for tRNA‐Guanine Transglycosylase (TGT)
EA Meyer, N Donati, M Guillot, WB Schweizer, F Diederich, B Stengl, ...
Helvetica chimica acta 89 (4), 573-597, 2006
472006
Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening
R Brenk, EA Meyer, K Reuter, MT Stubbs, GA Garcia, F Diederich, ...
Journal of molecular biology 338 (1), 55-75, 2004
472004
Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre
C Grimm, A Evers, M Brock, C Maerker, G Klebe, W Buckel, K Reuter
Journal of molecular biology 328 (3), 609-621, 2003
462003
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Artiklar 1–20