Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4′-phosphopantetheinyl transferase superfamily K Reuter, MR Mofid, MA Marahiel, R Ficner The EMBO journal 18 (23), 6823-6831, 1999 | 264 | 1999 |
Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis K Reuter, S Sanderbrand, H Jomaa, J Wiesner, I Steinbrecher, E Beck, ... Journal of Biological Chemistry 277 (7), 5378-5384, 2002 | 187 | 2002 |
Crystal structure of tRNA‐guanine transglycosylase: RNA modification by base exchange. C Romier, K Reuter, D Suck, R Ficner The EMBO journal 15 (11), 2850-2857, 1996 | 160 | 1996 |
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis R Brenk, L Naerum, U Grädler, HD Gerber, GA Garcia, K Reuter, ... Journal of medicinal chemistry 46 (7), 1133-1143, 2003 | 128 | 2003 |
The crystal structure of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain … C Grimm, E Maser, E Möbus, G Klebe, K Reuter, R Ficner Journal of Biological Chemistry 275 (52), 41333-41339, 2000 | 116 | 2000 |
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase U Grädler, HD Gerber, DAM Goodenough-Lashua, GA Garcia, R Ficner, ... Journal of Molecular Biology 306 (3), 455-467, 2001 | 104 | 2001 |
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes K Reuter, R Slany, F Ullrich, H Kersten Journal of bacteriology 173 (7), 2256-2264, 1991 | 98 | 1991 |
Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein K Reuter, S Nottrott, P Fabrizio, R Lührmann, R Ficner Journal of molecular biology 294 (2), 515-525, 1999 | 97 | 1999 |
Mechanism and Substrate Specificity of tRNA–Guanine Transglycosylases (TGTs): tRNA‐Modifying Enzymes from the Three Different Kingdoms of Life Share a Common Catalytic Mechanism B Stengl, K Reuter, G Klebe ChemBioChem 6 (11), 1926-1939, 2005 | 95 | 2005 |
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron (II) and 2-oxoglutarate-dependent dioxygenase EctD K Reuter, M Pittelkow, J Bursy, A Heine, T Craan, E Bremer PloS one 5 (5), e10647, 2010 | 83 | 2010 |
Mutagenesis and Crystallographic Studies of Zymomonas mobilis tRNA-Guanine Transglycosylase Reveal Aspartate 102 as the Active Site Nucleophile, C Romier, K Reuter, D Suck, R Ficner Biochemistry 35 (49), 15734-15739, 1996 | 64 | 1996 |
Sequence analysis and overexpression of the Zymomonas mobilis tgt gene encoding tRNA-guanine transglycosylase: purification and biochemical characterization of the enzyme K Reuter, R Ficner Journal of bacteriology 177 (18), 5284-5288, 1995 | 57 | 1995 |
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction T Ritschel, C Atmanene, K Reuter, A Van Dorsselaer, ... Journal of molecular biology 393 (4), 833-847, 2009 | 56 | 2009 |
A novel recessive hyperekplexia allele GLRA1 (S231R): genotyping by MALDI-TOF mass spectrometry and functional characterisation as a determinant of cellular glycine receptor … A Humeny, T Bonk, K Becker, M Jafari-Boroujerdi, U Stephani, K Reuter, ... European Journal of Human Genetics 10 (3), 188-196, 2002 | 55 | 2002 |
Flexible Adaptations in the Structure of the tRNA‐Modifying Enzyme tRNA–Guanine Transglycosylase and Their Implications for Substrate Selectivity, Reaction Mechanism and … R Brenk, MT Stubbs, A Heine, K Reuter, G Klebe ChemBioChem 4 (10), 1066-1077, 2003 | 49 | 2003 |
3α-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance, three-dimensional structure and gene regulation E Maser, G Xiong, C Grimm, R Ficner, K Reuter Chemico-Biological Interactions 130, 707-722, 2001 | 49 | 2001 |
Purification, crystallization, and preliminary X‐ray diffraction studies of tRNA‐guanine transglycosylase from Zymomonas mobilis C Romier, R Ficner, K Reuter, D Suck Proteins: Structure, Function, and Bioinformatics 24 (4), 516-519, 1996 | 49 | 1996 |
Synthesis, Biological Evaluation, and Crystallographic Studies of Extended Guanine‐Based (lin‐Benzoguanine) Inhibitors for tRNA‐Guanine Transglycosylase (TGT) EA Meyer, N Donati, M Guillot, WB Schweizer, F Diederich, B Stengl, ... Helvetica chimica acta 89 (4), 573-597, 2006 | 47 | 2006 |
Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening R Brenk, EA Meyer, K Reuter, MT Stubbs, GA Garcia, F Diederich, ... Journal of molecular biology 338 (1), 55-75, 2004 | 47 | 2004 |
Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre C Grimm, A Evers, M Brock, C Maerker, G Klebe, W Buckel, K Reuter Journal of molecular biology 328 (3), 609-621, 2003 | 46 | 2003 |