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John Platig
John Platig
Assistant Prof. University of Virginia
Verifierad e-postadress på virginia.edu
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Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
Y Yang, AL Shaffer, NC Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer Cell 21 (6), 723–737, 2012
5842012
Understanding tissue-specific gene regulation
AR Sonawane, J Platig, M Fagny, CY Chen, JN Paulson, ...
Cell reports 21 (4), 1077-1088, 2017
3682017
Sex differences in gene expression and regulatory networks across 29 human tissues
CM Lopes-Ramos, CY Chen, ML Kuijjer, JN Paulson, AR Sonawane, ...
Cell reports 31 (12), 2020
2332020
Exploring regulation in tissues with eQTL networks
M Fagny, JN Paulson, ML Kuijjer, AR Sonawane, CY Chen, ...
Proceedings of the National Academy of Sciences 114 (37), E7841-E7850, 2017
962017
External periodic driving of large systems of globally coupled phase oscillators
TM Antonsen, RT Faghih, M Girvan, E Ott, J Platig
Chaos: An Interdisciplinary Journal of Nonlinear Science 18 (3), 2008
962008
Bipartite community structure of eQTLs
J Platig, PJ Castaldi, D DeMeo, J Quackenbush
PLoS computational biology 12 (9), e1005033, 2016
622016
Regulatory network changes between cell lines and their tissues of origin
CM Lopes-Ramos, JN Paulson, CY Chen, ML Kuijjer, M Fagny, J Platig, ...
BMC genomics 18, 1-13, 2017
552017
Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface
X Carette, J Platig, DC Young, M Helmel, AT Young, Z Wang, LP Potluri, ...
MBio 9 (2), 10.1128/mbio. 02333-17, 2018
542018
Tissue-aware RNA-Seq processing and normalization for heterogeneous and sparse data
JN Paulson, CY Chen, CM Lopes-Ramos, ML Kuijjer, J Platig, ...
BMC bioinformatics 18, 1-10, 2017
512017
Thermodynamic measures of cancer: Gibbs free energy and entropy of protein–protein interactions
EA Rietman, J Platig, JA Tuszynski, G Lakka Klement
Journal of biological physics 42, 339-350, 2016
452016
GRAND: a database of gene regulatory network models across human conditions
M Ben Guebila, CM Lopes-Ramos, D Weighill, AR Sonawane, R Burkholz, ...
Nucleic Acids Research 50 (D1), D610-D621, 2022
422022
Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility
J Zeng, J Platig, TY Cheng, S Ahmed, Y Skaf, LP Potluri, D Schwartz, ...
PLoS Pathogens 16 (4), e1008452, 2020
382020
Robustness of network measures to link errors
J Platig, E Ott, M Girvan
Physical Review E 88 (6), 062812, 2013
372013
Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function
M Fagny, J Platig, ML Kuijjer, X Lin, J Quackenbush
British journal of cancer 122 (4), 569-577, 2020
362020
Echo phenomena in large systems of coupled oscillators
E Ott, JH Platig, TM Antonsen, M Girvan
Chaos: An Interdisciplinary Journal of Nonlinear Science 18 (3), 2008
332008
Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts
MM Parker, Y Hao, F Guo, B Pham, R Chase, J Platig, MH Cho, CP Hersh, ...
Elife 8, e42720, 2019
272019
Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease
JD Morrow, MH Cho, J Platig, X Zhou, DL DeMeo, W Qiu, B Celli, ...
Human genomics 12, 1-12, 2018
272018
Sexual dimorphism in gene expression and regulatory networks across human tissues
CY Chen, C Lopes-Ramos, ML Kuijjer, JN Paulson, AR Sonawane, ...
BioRxiv, 082289, 2016
262016
Gene regulatory network inference as relaxed graph matching
D Weighill, MB Guebila, C Lopes-Ramos, K Glass, J Quackenbush, ...
Proceedings of the AAAI Conference on Artificial Intelligence 35 (11), 10263 …, 2021
162021
Histopathological image QTL discovery of immune infiltration variants
JD Barry, M Fagny, JN Paulson, HJWL Aerts, J Platig, J Quackenbush
Iscience 5, 80-89, 2018
16*2018
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Artiklar 1–20