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Iain MacPhee
Iain MacPhee
Professor of Renal Medicine, St. George's, University of London
Verifierad e-postadress på sgul.ac.uk
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing
KA Birdwell, B Decker, JM Barbarino, JF Peterson, CM Stein, W Sadee, ...
Clinical Pharmacology & Therapeutics 98 (1), 19-24, 2015
6472015
Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report
M Brunet, T Van Gelder, A Åsberg, V Haufroid, DA Hesselink, L Langman, ...
Therapeutic drug monitoring 41 (3), 261-307, 2019
5002019
Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement
IAM Macphee, S Fredericks, T Tai, P Syrris, ND Carter, A Johnston, ...
Transplantation 74 (11), 1486-1489, 2002
4272002
Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids.
IA MacPhee, FA Antoni, DW Mason
The Journal of experimental medicine 169 (2), 431-445, 1989
3851989
The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation
IAM MacPhee, S Fredericks, T Tai, P Syrris, ND Carter, A Johnston, ...
American Journal of Transplantation 4 (6), 914-919, 2004
3112004
Tacrolimus pharmacogenetics: the CYP3A5* 1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians
IAM MacPhee, S Fredericks, M Mohamed, M Moreton, ND Carter, ...
Transplantation 79 (4), 499-502, 2005
2612005
The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat.
D Mason, I MacPhee, F Antoni
Immunology 70 (1), 1, 1990
2401990
European Society for Organ Transplantation Advisory Committee recommendations on generic substitution of immunosuppressive drugs
T van Gelder
Transplant International 24 (12), 1135-1141, 2011
1112011
A renal registry for Africa: first steps
MR Davids, JB Eastwood, NH Selwood, FA Arogundade, G Ashuntantang, ...
Clinical kidney journal 9 (1), 162-167, 2016
1092016
Biomarkers of tolerance in kidney transplantation: are we predicting tolerance or response to immunosuppressive treatment?
I Rebollo-Mesa, E Nova-Lamperti, P Mobillo, M Runglall, S Christakoudi, ...
American Journal of Transplantation 16 (12), 3443-3457, 2016
1082016
Renohepatic crosstalk: does acute kidney injury cause liver dysfunction?
K Lane, JJ Dixon, IAM MacPhee, BJ Philips
Nephrology dialysis transplantation 28 (7), 1634-1647, 2013
992013
Isolation of encephalitogenic CD4+ T cell clones in the rat: Cloning methodology and interferon-γ secretion
JD Sedgwick, IAM MacPhee, M Puklavec
Journal of immunological methods 121 (2), 185-196, 1989
911989
LONG-TERM OUTCOME OF A PROSPECTIVE RANDOMIZED TRIAL OF CONVERSION FROM CYCLOSPORINE TO AZATHIOPRINE TREATMENT ONE YEAR AFTER RENAL TRANSPLANTATION1
IAM MacPhee, JA Bradley, JD Briggs, BJR Junor, SG MacPherson, ...
Transplantation 66 (9), 1186-1192, 1998
841998
Plasma concentrations of mycophenolic acid acyl glucuronide are not associated with diarrhea in renal transplant recipients
T Heller, T Van Gelder, K Budde, JW De Fijter, D Kuypers, W Arns, ...
American journal of transplantation 7 (7), 1822-1831, 2007
822007
Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements
S Fredericks, M Moreton, S Reboux, ND Carter, L Goldberg, DW Holt, ...
Transplantation 82 (5), 705-708, 2006
802006
Pharmacokinetics of mycophenolate mofetil in patients with end-stage renal failure
IAM MacPhee, S Spreafico, M Bewick, C Davis, JB Eastwood, A Johnston, ...
Kidney international 57 (3), 1164-1168, 2000
752000
A pharmacogenetic strategy for immunosuppression based on the CYP3A5 genotype
IAM MacPhee, DW Holt
Transplantation 85 (2), 163-165, 2008
672008
Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients
CJ Kirwan, IAM MacPhee, T Lee, DW Holt, BJ Philips
Intensive care medicine 38, 76-84, 2012
652012
Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are not associated with cyclosporine pharmacokinetics nor with cyclosporine clinical end points after renal transplantation
R Bouamar, DA Hesselink, RHN van Schaik, W Weimar, IAM MacPhee, ...
Therapeutic drug monitoring 33 (2), 178-184, 2011
652011
Antigen-specific damage to brain vascular endothelial cells mediated by encephalitogenic and nonencephalitogenic CD4+ T cell lines in vitro.
JD Sedgwick, CC Hughes, DK Male, IA MacPhee, V ter Meulen
Journal of immunology (Baltimore, Md.: 1950) 145 (8), 2474-2481, 1990
651990
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