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Klara Stefflova
Klara Stefflova
Caltech
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Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
RA Eeles, Z Kote-Jarai, AA Al Olama, GG Giles, M Guy, G Severi, K Muir, ...
Nature genetics 41 (10), 1116-1121, 2009
4872009
Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation
G Zheng, J Chen, K Stefflova, M Jarvi, H Li, BC Wilson
Proceedings of the National Academy of Sciences 104 (21), 8989-8994, 2007
3492007
Rapid turnover of long noncoding RNAs and the evolution of gene expression
C Kutter, S Watt, K Stefflova, MD Wilson, A Goncalves, CP Ponting, ...
PLoS genetics 8 (7), e1002841, 2012
3392012
Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation
J Chen, K Stefflova, MJ Niedre, BC Wilson, B Chance, JD Glickson, ...
Journal of the American Chemical Society 126 (37), 11450-11451, 2004
2002004
Extensive compensatory cis-trans regulation in the evolution of mouse gene expression
A Goncalves, S Leigh-Brown, D Thybert, K Stefflova, E Turro, P Flicek, ...
Genome research 22 (12), 2376-2384, 2012
1762012
Cooperativity and rapid evolution of cobound transcription factors in closely related mammals
K Stefflova, D Thybert, MD Wilson, I Streeter, J Aleksic, P Karagianni, ...
Cell 154 (3), 530-540, 2013
1722013
Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent
K Stefflova, H Li, J Chen, G Zheng
Bioconjugate chemistry 18 (2), 379-388, 2007
1382007
Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers
PC Lo, J Chen, K Stefflova, MS Warren, R Navab, B Bandarchi, S Mullins, ...
Journal of medicinal chemistry 52 (2), 358-368, 2009
1312009
Validation of genome-wide prostate cancer associations in men of African descent
BL Chang, E Spangler, S Gallagher, CA Haiman, B Henderson, W Isaacs, ...
Cancer epidemiology, biomarkers & prevention 20 (1), 23-32, 2011
1202011
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways
B Ballester, A Medina-Rivera, D Schmidt, M Gonzàlez-Porta, M Carlucci, ...
Elife 3, e02626, 2014
1142014
Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains
E Kentepozidou, SJ Aitken, C Feig, K Stefflova, X Ibarra-Soria, DT Odom, ...
Genome biology 21, 1-19, 2020
1102020
Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ
K Stefflova, J Chen, D Marotta, H Li, G Zheng
Journal of medicinal chemistry 49 (13), 3850-3856, 2006
942006
Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes
D Thybert, M Roller, FCP Navarro, I Fiddes, I Streeter, C Feig, ...
Genome research 28 (4), 448-459, 2018
922018
A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production
J Chen, JF Lovell, PC Lo, K Stefflova, M Niedre, BC Wilson, G Zheng
Photochemical & Photobiological Sciences 7 (7), 775-781, 2008
802008
Using molecular beacons for cancer imaging and treatment
K Stefflova, J Chen, G Zheng
Front Biosci 12 (12), 4709-4721, 2007
752007
Dissecting the within-Africa ancestry of populations of African descent in the Americas
K Stefflova, MC Dulik, JS Barnholtz-Sloan, AA Pai, AH Walker, ...
Plos one 6 (1), e14495, 2011
672011
Killer beacons for combined cancer imaging and therapy
K Stefflova, J Chen, G Zheng
Current medicinal chemistry 14 (20), 2110-2125, 2007
592007
Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals
ES Wong, D Thybert, BM Schmitt, K Stefflova, DT Odom, P Flicek
Genome research 25 (2), 167-178, 2015
562015
In Vivo Detection of Phospholipase C by Enzyme-Activated Near-Infrared Probes
TM Mawn, AV Popov, NJ Beardsley, K Stefflova, M Milkevitch, G Zheng, ...
Bioconjugate Chemistry 22 (12), 2434-2443, 2011
472011
Targeted photodynamic therapy agent with a built-in apoptosis sensor for in vivo near-infrared imaging of tumor apoptosis triggered by its photosensitization in situ
K Stefflova, J Chen, H Li, G Zheng
Molecular imaging 5 (4), 7290.2006. 00027, 2006
452006
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Artiklar 1–20