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Fredrik Karpe
Fredrik Karpe
Professor of Metabolic Medicine
Verifierad e-postadress på ocdem.ox.ac.uk - Startsida
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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ...
Science 316 (5826), 889-894, 2007
55442007
Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
45812015
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ...
Nature genetics 42 (11), 937-948, 2010
35052010
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
24762010
Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ...
Nature genetics 40 (6), 768-775, 2008
15612008
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ...
Nature genetics 42 (11), 949-960, 2010
10902010
Fatty acids, obesity, and insulin resistance: time for a reevaluation
F Karpe, JR Dickmann, KN Frayn
Diabetes 60 (10), 2441-2449, 2011
10292011
Gluteofemoral body fat as a determinant of metabolic health
KN Manolopoulos, F Karpe, KN Frayn
International journal of obesity 34 (6), 949-959, 2010
8902010
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, ...
Nature genetics 45 (5), 501-512, 2013
7322013
Integrative physiology of human adipose tissue
KN Frayn, F Karpe, BA Fielding, IA Macdonald, SW Coppack
International journal of obesity 27 (8), 875-888, 2003
7262003
Postprandial lipoproteins and progression of coronary atherosclerosis
F Karpe, G Steiner, K Uffelman, T Olivecrona, A Hamsten
Atherosclerosis 106 (1), 83-97, 1994
6401994
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
CM Lindgren, IM Heid, JC Randall, C Lamina, V Steinthorsdottir, L Qi, ...
PLoS genetics 5 (6), e1000508, 2009
6192009
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ
DB Savage, GD Tan, CL Acerini, SA Jebb, M Agostini, M Gurnell, ...
Diabetes 52 (4), 910-917, 2003
5762003
Physical activity and exercise in the regulation of human adipose tissue physiology
D Thompson, F Karpe, M Lafontan, K Frayn
Physiological reviews, 2012
4942012
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, ...
PLoS genetics 9 (6), e1003500, 2013
4652013
Remodeling phenotype of human subcutaneous adipose tissue macrophages
V Bourlier, A Zakaroff-Girard, A Miranville, S De Barros, M Maumus, ...
Circulation 117 (6), 806-815, 2008
4462008
Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?
SE McQuaid, L Hodson, MJ Neville, AL Dennis, J Cheeseman, ...
Diabetes 60 (1), 47-55, 2011
4282011
Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI
RM Freathy, NJ Timpson, DA Lawlor, A Pouta, Y Ben-Shlomo, ...
Diabetes 57 (5), 1419-1426, 2008
4272008
Plasma tumour necrosis factor-α and early carotid atherosclerosis in healthy middle-aged men
T Skoog, W Dichtl, S Boquist, C Skoglund-Andersson, F Karpe, R Tang, ...
European heart journal 23 (5), 376-383, 2002
4272002
Activation of peroxisome proliferator–activated receptor (PPAR) δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid …
U Risérus, D Sprecher, T Johnson, E Olson, S Hirschberg, A Liu, Z Fang, ...
Diabetes 57 (2), 332-339, 2008
3582008
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