PopED: An extended, parallelized, nonlinear mixed effects models optimal design tool J Nyberg, S Ueckert, EA Strömberg, S Hennig, MO Karlsson, AC Hooker Computer Methods and Programs in Biomedicine, 2012 | 121 | 2012 |
Improved utilization of ADAS-cog assessment data through item response theory based pharmacometric modeling S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker, ... Pharmaceutical research 31, 2152-2165, 2014 | 99 | 2014 |
Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled … HJL Heerspink, A Kiyosue, DC Wheeler, M Lin, E Wijkmark, G Carlson, ... The Lancet 402 (10416), 2004-2017, 2023 | 56 | 2023 |
Comparison of model averaging and model selection in dose finding trials analyzed by nonlinear mixed effect models S Buatois, S Ueckert, N Frey, S Retout, F Mentré The AAPS journal 20, 1-9, 2018 | 49 | 2018 |
Item response theory as an efficient tool to describe a heterogeneous clinical rating scale in de novo idiopathic Parkinson’s disease patients S Buatois, S Retout, N Frey, S Ueckert Pharmaceutical research 34 (10), 2109-2118, 2017 | 47 | 2017 |
Modeling composite assessment data using item response theory S Ueckert CPT: Pharmacometrics & Systems Pharmacology 7 (4), 205-218, 2018 | 43 | 2018 |
Application of item response theory to modeling of expanded disability status scale in multiple sclerosis AM Novakovic, EHJ Krekels, A Munafo, S Ueckert, MO Karlsson The AAPS journal 19, 172-179, 2017 | 43 | 2017 |
Evaluation of bias, precision, robustness and runtime for estimation methods in NONMEM 7 ÅM Johansson, S Ueckert, EL Plan, AC Hooker, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 41, 223-238, 2014 | 39 | 2014 |
A new method for evaluation of the Fisher information matrix for discrete mixed effect models using Monte Carlo sampling and adaptive Gaussian quadrature S Ueckert, F Mentré Computational Statistics & Data Analysis 111, 203-219, 2017 | 22 | 2017 |
An MCMC method for the evaluation of the Fisher information matrix for non-linear mixed effect models MK Riviere, S Ueckert, F Mentré Biostatistics 17 (4), 737-750, 2016 | 22 | 2016 |
Accelerating Monte Carlo power studies through parametric power estimation S Ueckert, MO Karlsson, AC Hooker Journal of pharmacokinetics and pharmacodynamics 43, 223-234, 2016 | 21 | 2016 |
Performance of longitudinal item response theory models in shortened or partial assessments L Arrington, S Ueckert, M Ahamadi, S Macha, MO Karlsson Journal of Pharmacokinetics and Pharmacodynamics 47, 461-471, 2020 | 13 | 2020 |
A novel BACE inhibitor (PF-05297909):: A two-part adaptive design to evaluate safety, pharmacokinetics and pharmacodynamics for modifying beta-amyloid in a first-in-human study J Bell, B ONeill, M Brodney, E Hajos-Korcsok, Y Lu, D Riddell, K Ito, ... Alzheimer's & Dementia: Journal of the Alzheimer's Association 9 (4), P287, 2013 | 11 | 2013 |
Xpose and Perl speaks NONMEM (PsN) K Harling, S Ueckert, AC Hooker, EN Jonsson, MO Karlsson Population Approach Group Europe (PAGE), Berlin, 2010 | 10 | 2010 |
Application of Item Response Theory to ADAS-cog Scores Modelling in Alzheimer’s Disease S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker PAGE 21 (2012), 2012 | 9 | 2012 |
cLRT‐Mod: An efficient methodology for pharmacometric model‐based analysis of longitudinal Phase II dose finding studies under model uncertainty S Buatois, S Ueckert, N Frey, S Retout, F Mentré Statistics in Medicine 40 (10), 2435-2451, 2021 | 8 | 2021 |
Handling Below Limit of Quantification Data in Optimal Trial Design C Vong, S Ueckert, J Nyberg, AC Hooker PAGE 21 (2012), 2012 | 8 | 2012 |
An item response theory–informed strategy to model total score data from composite scales GJ Wellhagen, S Ueckert, MC Kjellsson, MO Karlsson The AAPS Journal 23, 1-10, 2021 | 6 | 2021 |
Modeling the Neuropsychiatric Inventory (NPI)-Strengths and Weaknesses of a Multidimensional Item Response Theory Approach S Ueckert, P Lockwood, P Schwartz, S Riley Journal of Pharmacokinetics and Pharmacodynamics 42 (S1), S92-S92, 2015 | 6 | 2015 |
Optimizing disease progression study designs for drug effect discrimination S Ueckert, S Hennig, J Nyberg, MO Karlsson, AC Hooker Journal of pharmacokinetics and pharmacodynamics 40, 587-596, 2013 | 6 | 2013 |