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Sebastian Ueckert
Sebastian Ueckert
Verified email at farmbio.uu.se
Title
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Cited by
Year
PopED: An extended, parallelized, nonlinear mixed effects models optimal design tool
J Nyberg, S Ueckert, EA Strömberg, S Hennig, MO Karlsson, AC Hooker
Computer Methods and Programs in Biomedicine, 2012
1122012
Improved utilization of ADAS-cog assessment data through item response theory based pharmacometric modeling
S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker, ...
Pharmaceutical research 31, 2152-2165, 2014
902014
Comparison of model averaging and model selection in dose finding trials analyzed by nonlinear mixed effect models
S Buatois, S Ueckert, N Frey, S Retout, F Mentré
The AAPS journal 20, 1-9, 2018
432018
Item response theory as an efficient tool to describe a heterogeneous clinical rating scale in de novo idiopathic Parkinson’s disease patients
S Buatois, S Retout, N Frey, S Ueckert
Pharmaceutical research 34 (10), 2109-2118, 2017
372017
Application of item response theory to modeling of expanded disability status scale in multiple sclerosis
AM Novakovic, EHJ Krekels, A Munafo, S Ueckert, MO Karlsson
The AAPS journal 19, 172-179, 2017
352017
Evaluation of bias, precision, robustness and runtime for estimation methods in NONMEM 7
ÅM Johansson, S Ueckert, EL Plan, AC Hooker, MO Karlsson
Journal of pharmacokinetics and pharmacodynamics 41, 223-238, 2014
332014
Modeling composite assessment data using item response theory
S Ueckert
CPT: Pharmacometrics & Systems Pharmacology 7 (4), 205-218, 2018
312018
A new method for evaluation of the Fisher information matrix for discrete mixed effect models using Monte Carlo sampling and adaptive Gaussian quadrature
S Ueckert, F Mentré
Computational statistics & data analysis 111, 203-219, 2017
222017
An MCMC method for the evaluation of the Fisher information matrix for non-linear mixed effect models
MK Riviere, S Ueckert, F Mentré
Biostatistics 17 (4), 737-750, 2016
222016
Accelerating Monte Carlo power studies through parametric power estimation
S Ueckert, MO Karlsson, AC Hooker
Journal of pharmacokinetics and pharmacodynamics 43, 223-234, 2016
192016
Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled …
HJL Heerspink, A Kiyosue, DC Wheeler, M Lin, E Wijkmark, G Carlson, ...
The Lancet 402 (10416), 2004-2017, 2023
132023
A novel BACE inhibitor (PF-05297909):: A two-part adaptive design to evaluate safety, pharmacokinetics and pharmacodynamics for modifying beta-amyloid in a first-in-human study
J Bell, B ONeill, M Brodney, E Hajos-Korcsok, Y Lu, D Riddell, K Ito, ...
Alzheimer's & Dementia: Journal of the Alzheimer's Association 9 (4), P287, 2013
102013
Xpose and Perl speaks NONMEM (PsN)
K Harling, S Ueckert, AC Hooker, EN Jonsson, MO Karlsson
Population Approach Group Europe (PAGE), Berlin, 2010
102010
Application of Item Response Theory to ADAS-cog Scores Modelling in Alzheimer’s Disease
S Ueckert, EL Plan, K Ito, MO Karlsson, B Corrigan, AC Hooker
PAGE 21 (2012), 2012
92012
Performance of longitudinal item response theory models in shortened or partial assessments
L Arrington, S Ueckert, M Ahamadi, S Macha, MO Karlsson
Journal of Pharmacokinetics and Pharmacodynamics 47, 461-471, 2020
82020
Handling Below Limit of Quantification Data in Optimal Trial Design
C Vong, S Ueckert, J Nyberg, AC Hooker
PAGE 21 (2012), 2012
82012
Modeling the Neuropsychiatric Inventory (NPI)-Strengths and Weaknesses of a Multidimensional Item Response Theory Approach
S Ueckert, P Lockwood, P Schwartz, S Riley
Journal of Pharmacokinetics and Pharmacodynamics 42 (S1), S92-S92, 2015
62015
Optimizing disease progression study designs for drug effect discrimination
S Ueckert, S Hennig, J Nyberg, MO Karlsson, AC Hooker
Journal of pharmacokinetics and pharmacodynamics 40, 587-596, 2013
62013
Application of Item Response Theory to EDSS Modeling in Multiple Sclerosis
A Kalezic, R Savic, A Munafo, S Ueckert, M Karlsson
PAGE, 2013
62013
cLRT‐Mod: An efficient methodology for pharmacometric model‐based analysis of longitudinal Phase II dose finding studies under model uncertainty
S Buatois, S Ueckert, N Frey, S Retout, F Mentré
Statistics in Medicine 40 (10), 2435-2451, 2021
52021
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Articles 1–20