| Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy N Cartier, S Hacein-Bey-Abina, CC Bartholomae, G Veres, M Schmidt, ... science 326 (5954), 818-823, 2009 | 1727 | 2009 |
| Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia M Cavazzana-Calvo, E Payen, O Negre, G Wang, K Hehir, F Fusil, ... Nature 467 (7313), 318-322, 2010 | 1587 | 2010 |
| Adeno-associated virus-based gene therapy for CNS diseases M Hocquemiller, L Giersch, M Audrain, S Parker, N Cartier Human gene therapy 27 (7), 478-496, 2016 | 304 | 2016 |
| A two-year trial of oleic and erucic acids (“Lorenzo's oil”) as treatment for adrenomyeloneuropathy P Aubourg, C Adamsbaum, MC Lavallard-Rousseau, F Rocchiccioli, ... New England Journal of Medicine 329 (11), 745-752, 1993 | 301 | 1993 |
| Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection A Biffi, CC Bartolomae, D Cesana, N Cartier, P Aubourg, M Ranzani, ... Blood, The Journal of the American Society of Hematology 117 (20), 5332-5339, 2011 | 270 | 2011 |
| Glucose transporter 2 (GLUT 2): expression in specific brain nuclei C Leloup, M Arluison, N Lepetit, N Cartier, P Marfaing-Jallat, P Ferré, ... Brain research 638 (1-2), 221-226, 1994 | 243 | 1994 |
| Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia M Perdomini, B Belbellaa, L Monassier, L Reutenauer, N Messaddeq, ... Nature medicine 20 (5), 542-547, 2014 | 233 | 2014 |
| Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's … E Hudry, D Van Dam, W Kulik, PP De Deyn, FS Stet, O Ahouansou, ... Molecular Therapy 18 (1), 44-53, 2010 | 210 | 2010 |
| Human CD34+ cells differentiate into microglia and express recombinant therapeutic protein M Asheuer, F Pflumio, S Benhamida, A Dubart-Kupperschmitt, F Fouquet, ... Proceedings of the National Academy of Sciences 101 (10), 3557-3562, 2004 | 209 | 2004 |
| CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease F Djelti, J Braudeau, E Hudry, M Dhenain, J Varin, I Bieche, C Marquer, ... Brain 138 (8), 2383-2398, 2015 | 198 | 2015 |
| Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model R Fol, J Braudeau, S Ludewig, T Abel, SW Weyer, JP Roederer, F Brod, ... Acta neuropathologica 131, 247-266, 2016 | 184 | 2016 |
| Homo-and heterodimerization of peroxisomal ATP-binding cassette half-transporters LX Liu, K Janvier, V Berteaux-Lecellier, N Cartier, R Benarous, P Aubourg Journal of Biological Chemistry 274 (46), 32738-32743, 1999 | 182 | 1999 |
| Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. L Miquerol, S Lopez, N Cartier, M Tulliez, M Raymondjean, A Kahn Journal of Biological Chemistry 269 (12), 8944-8951, 1994 | 179 | 1994 |
| Hematopoietic stem cell transplantation and hematopoietic stem cell gene therapy in X‐linked adrenoleukodystrophy N Cartier, P Aubourg Brain pathology 20 (4), 857-862, 2010 | 172 | 2010 |
| CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease L Boussicault, S Alves, A Lamazière, A Planques, N Heck, L Moumné, ... Brain 139 (3), 953-970, 2016 | 164 | 2016 |
| Lentiviral hematopoietic cell gene therapy for X-linked adrenoleukodystrophy N Cartier, S Hacein-Bey-Abina, CC Bartholomae, P Bougnères, ... Methods in enzymology 507, 187-198, 2012 | 161 | 2012 |
| Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice S Alves, G Churlaud, M Audrain, K Michaelsen-Preusse, R Fol, B Souchet, ... Brain 140 (3), 826-842, 2017 | 154 | 2017 |
| Discrete brain areas express the insulin-responsive glucose transporter GLUT4 C Leloup, M Arluison, N Kassis, N Lepetit, N Cartier, P Ferré, L Pénicaud Molecular Brain Research 38 (1), 45-53, 1996 | 153 | 1996 |
| Deficiency of long-chain 3-hydroxyacyl-CoA dehydrogenase: a cause of lethal myopathy and cardiomyopathy in early childhood F Rocchicciolo, RJA Wanders, P Aubourg, C Vianey-Liaud, L Ijlst, ... Pediatric research 28 (6), 657-662, 1990 | 134 | 1990 |
| Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts. N Cartier, J LoPEZ, P Moullier, F RocCHICCIOLI, MO Rolland, P Jorge, ... Proceedings of the National Academy of Sciences 92 (5), 1674-1678, 1995 | 133 | 1995 |
