| Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome E Porcu, MC Sadler, K Lepik, C Auwerx, AR Wood, A Weihs, ... Nature communications 12 (1), 5647, 2021 | 69 | 2021 |
| The individual and global impact of copy-number variants on complex human traits C Auwerx, M Lepamets, MC Sadler, M Patxot, M Stojanov, D Baud, ... The American Journal of Human Genetics 109 (4), 647-668, 2022 | 44 | 2022 |
| Sex-and age-dependent genetics of longevity in a heterogeneous mouse population M Bou Sleiman, S Roy, AW Gao, MC Sadler, GVG von Alvensleben, H Li, ... Science 377 (6614), eabo3191, 2022 | 28 | 2022 |
| Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease B Ponte, MC Sadler, E Olinger, P Vollenweider, M Bochud, ... Kidney international 100 (6), 1282-1291, 2021 | 27 | 2021 |
| From pharmacogenetics to pharmaco-omics: Milestones and future directions C Auwerx, MC Sadler, A Reymond, Z Kutalik Human Genetics and Genomics Advances 3 (2), 2022 | 23 | 2022 |
| Causality-enriched epigenetic age uncouples damage and adaptation K Ying, H Liu, AE Tarkhov, MC Sadler, AT Lu, M Moqri, S Horvath, ... Nature Aging, 1-16, 2024 | 18 | 2024 |
| Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations C Auwerx, MC Sadler, T Woh, A Reymond, Z Kutalik, E Porcu Elife 12, e81097, 2023 | 11 | 2023 |
| Multi-layered genetic approaches to identify approved drug targets MC Sadler, C Auwerx, P Deelen, Z Kutalik Cell Genomics 3 (7), 2023 | 10 | 2023 |
| Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases MC Sadler, C Auwerx, K Lepik, E Porcu, Z Kutalik Nature Communications 13 (1), 7559, 2022 | 10 | 2022 |
| Computational surveillance of microbial water quality with online flow cytometry MC Sadler, J Senouillet, S Kuenzi, L Grasso, DC Watson Frontiers in Water 2, 586969, 2020 | 10 | 2020 |
| Chromosomal deletions on 16p11. 2 encompassing SH2B1 are associated with accelerated metabolic disease R Hanssen, C Auwerx, M Jõeloo, MC Sadler, E Henning, J Keogh, ... Cell Reports Medicine 4 (8), 2023 | 7 | 2023 |
| Promises and challenges in pharmacoepigenetics DA Smith, MC Sadler, RB Altman Cambridge Prisms: Precision Medicine 1, e18, 2023 | 4 | 2023 |
| The impact of 22q11. 2 copy-number variants on human traits in the general population M Zamariolli, C Auwerx, MC Sadler, A van der Graaf, K Lepik, T Schoeler, ... The American Journal of Human Genetics 110 (2), 300-313, 2023 | 3 | 2023 |
| Possible association of 16p11. 2 copy number variation with altered lymphocyte and neutrophil counts G Giannuzzi, N Chatron, K Mannik, C Auwerx, S Pradervand, G Willemin, ... NPJ Genomic Medicine 7 (1), 38, 2022 | 3 | 2022 |
| Quantifying mediation between omics layers and complex traits MC Sadler, C Auwerx, E Porcu, Z Kutalik bioRxiv, 2021.09. 29.462396, 2021 | 3 | 2021 |
| Rare copy-number variants as modulators of common disease susceptibility C Auwerx, M Jõeloo, MC Sadler, N Tesio, S Ojavee, CJ Clark, R Mägi, ... Genome Medicine 16 (1), 5, 2024 | 2 | 2024 |
| Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset SE Ojavee, ES Maksimova, K Läll, MC Sadler, R Mägi, Z Kutalik, ... medRxiv, 2022.03. 25.22272955, 2022 | 2 | 2022 |
| Genetic association studies using disease liabilities from deep neural networks L Yang, MC Sadler, RB Altman medRxiv, 2023 | 1 | 2023 |
| Making genome editing a success story in Africa HM Abkallo, P Arbuthnot, TO Auer, DK Berger, J Burger, E Chakauya, ... Nature Biotechnology, 1-4, 2024 | | 2024 |
| Leveraging large-scale biobank EHRs to enhance pharmacogenetics of cardiometabolic disease medications MC Sadler, A Apostolov, C Cevallos, DM Ribeiro, RB Altman, Z Kutalik medRxiv, 2024.04. 06.24305415, 2024 | | 2024 |
