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Matthew Oser
Matthew Oser
Dana-Farber Cancer Institute
Verifierad e-postadress på dfci.harvard.edu
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Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin
MG Oser, MJ Niederst, LV Sequist, JA Engelman
The Lancet Oncology 16 (4), e165-e172, 2015
8292015
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ...
Journal of Cell Biology 186 (4), 571-587, 2009
4372009
Polycomb group protein ezh2 controls actin polymerization and cell signaling
I Su, MW Dobenecker, E Dickinson, M Oser, A Basavaraj, R Marqueron, ...
Cell 121 (3), 425-436, 2005
4202005
An EGFR–Src–Arg–cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion
CC Mader, M Oser, MAO Magalhaes, JJ Bravo-Cordero, J Condeelis, ...
Cancer research 71 (5), 1730-1741, 2011
3402011
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis
U Philippar, ET Roussos, M Oser, H Yamaguchi, HD Kim, S Giampieri, ...
Developmental cell 15 (6), 813-828, 2008
3362008
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway
MAO Magalhaes, DR Larson, CC Mader, JJ Bravo-Cordero, H Gil-Henn, ...
Journal of Cell Biology 195 (5), 903-920, 2011
2462011
The cofilin activity cycle in lamellipodia and invadopodia
M Oser, J Condeelis
Journal of cellular biochemistry 108 (6), 1252-1262, 2009
2252009
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia
JJ Bravo-Cordero, M Oser, X Chen, R Eddy, L Hodgson, J Condeelis
Current Biology 21 (8), 635-644, 2011
2212011
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia
M Oser, CC Mader, H Gil-Henn, M Magalhaes, JJ Bravo-Cordero, ...
Journal of cell science 123 (21), 3662-3673, 2010
1892010
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer
H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ...
Cancer cell 37 (1), 37-54. e9, 2020
1672020
New approaches to SCLC therapy: from the laboratory to the clinic
JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ...
Journal of Thoracic Oncology 15 (4), 520-540, 2020
1462020
N‐WASP and cortactin are involved in invadopodium‐dependent chemotaxis to EGF in breast tumor cells
V DesMarais, H Yamaguchi, M Oser, L Soon, G Mouneimne, C Sarmiento, ...
Cell motility and the cytoskeleton 66 (6), 303-316, 2009
1422009
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
MG Oser, R Fonseca, AA Chakraborty, R Brough, A Spektor, RB Jennings, ...
Cancer discovery 9 (2), 230-247, 2019
1382019
Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion
IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ...
Cell metabolism 29 (5), 1166-1181. e6, 2019
1262019
Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity
NR Mahadevan, EH Knelson, JO Wolff, A Vajdi, M Saigí, M Campisi, ...
Cancer discovery 11 (8), 1952-1969, 2021
932021
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis
MG Oser, AH Sabet, W Gao, AA Chakraborty, AC Schinzel, RB Jennings, ...
Genes & development 33 (23-24), 1718-1738, 2019
802019
Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes
M Oser, A Dovas, D Cox, J Condeelis
European journal of cell biology 90 (2-3), 181-188, 2011
702011
Cyclin D–CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB
AE Schade, MG Oser, HE Nicholson, JA DeCaprio
Oncogene 38 (25), 4962-4976, 2019
622019
Targeting oncoproteins with a positive selection assay for protein degraders
V Koduri, L Duplaquet, BL Lampson, AC Wang, AH Sabet, M Ishoey, ...
Science Advances 7 (6), eabd6263, 2021
282021
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
C Zhang, X Li, G Adelmant, J Dobbins, C Geisen, MG Oser, ...
Proceedings of the National Academy of Sciences 112 (50), 15372-15377, 2015
272015
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Artiklar 1–20