| TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway S Viel, A Marçais, FSF Guimaraes, R Loftus, J Rabilloud, M Grau, ... Science signaling 9 (415), ra19-ra19, 2016 | 573 | 2016 |
| Metabolic reprogramming of natural killer cells in obesity limits antitumor responses X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ... Nature immunology 19 (12), 1330-1340, 2018 | 485 | 2018 |
| mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function RP Donnelly, RM Loftus, SE Keating, KT Liou, CA Biron, CM Gardiner, ... The Journal of Immunology 193 (9), 4477-4484, 2014 | 448 | 2014 |
| Immunometabolism: cellular metabolism turns immune regulator RM Loftus, DK Finlay Journal of Biological Chemistry 291 (1), 1-10, 2016 | 445 | 2016 |
| Srebp-controlled glucose metabolism is essential for NK cell functional responses N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, ... Nature immunology 18 (11), 1197-1206, 2017 | 307 | 2017 |
| Metabolic reprogramming supports IFN-γ production by CD56bright NK cells SE Keating, V Zaiatz-Bittencourt, RM Loftus, C Keane, K Brennan, ... The Journal of Immunology 196 (6), 2552-2560, 2016 | 297 | 2016 |
| Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice RM Loftus, N Assmann, N Kedia-Mehta, KL O’Brien, A Garcia, C Gillespie, ... Nature communications 9 (1), 2341, 2018 | 289 | 2018 |
| Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments N Lopes, C McIntyre, S Martin, M Raverdeau, N Sumaria, AC Kohlgruber, ... Nature immunology 22 (2), 179-192, 2021 | 122 | 2021 |
| Obesity reduces mTORC1 activity in mucosal-associated invariant T cells, driving defective metabolic and functional responses A O’Brien, RM Loftus, MM Pisarska, LM Tobin, R Bergin, NAW Wood, ... The Journal of Immunology 202 (12), 3404-3411, 2019 | 62 | 2019 |
| Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function L Dyck, H Prendeville, M Raverdeau, MM Wilk, RM Loftus, A Douglas, ... Journal of Experimental Medicine 219 (3), 2022 | 54 | 2022 |
| Amino Acid-dependant MTORC1 and CMyc Signaling is Essential for Natural Killer Cell Metabolic and Functional Responses R Loftus Trinity College Dublin, 2017 | | 2017 |
