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Esa Pitkänen
Esa Pitkänen
Institute for Molecular Medicine Finland (FIMM)
Verifierad e-postadress på helsinki.fi - Startsida
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Pan-cancer analysis of whole genomes
PCAWG Consortium
Nature 578 (7793), 82, 2020
1690*2020
CTCF/cohesin-binding sites are frequently mutated in cancer
R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ...
Nature genetics 47 (7), 818-821, 2015
4552015
Characterization of uterine leiomyomas by whole-genome sequencing
M Mehine, E Kaasinen, N Mäkinen, R Katainen, K Kämpjärvi, E Pitkänen, ...
New England Journal of Medicine 369 (1), 43-53, 2013
3452013
The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera
V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ...
Nature communications 5 (1), 4737, 2014
2362014
Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers
M Mehine, E Kaasinen, HR Heinonen, N Mäkinen, K Kämpjärvi, ...
Proceedings of the National Academy of Sciences 113 (5), 1315-1320, 2016
2072016
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer
T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ...
International journal of cancer 135 (3), 611-623, 2014
1282014
Comparative Genome-Scale Reconstruction of Gapless Metabolic Networks for Present and Ancestral Species
E Pitkänen, P Jouhten, J Hou, MS Fahad, P Blomberg, J Kludas, M Oja, ...
PLOS Computational Biology 10 (2), e1003465, 2014
1062014
Whole-genome sequencing of growth hormone (GH)-secreting pituitary adenomas
N Välimäki, H Demir, E Pitkänen, E Kaasinen, A Karppinen, L Kivipelto, ...
The Journal of Clinical Endocrinology & Metabolism 100 (10), 3918-3927, 2015
1002015
Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer
AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ...
PLOS Genetics 9 (10), e1003876, 2013
952013
Inferring branching pathways in genome-scale metabolic networks
E Pitkänen, P Jouhten, J Rousu
BMC systems biology 3 (1), 103, 2009
902009
MED12 mutation frequency in unselected sporadic uterine leiomyomas
HR Heinonen, NS Sarvilinna, J Sjöberg, K Kämpjärvi, E Pitkänen, ...
Fertility and sterility 102 (4), 1137-1142, 2014
812014
Identification of 33 candidate oncogenes by screening for base-specific mutations
S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ...
British journal of cancer 111 (8), 1657-1662, 2014
782014
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability
AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ...
Gastroenterology 145 (3), 540-543. e22, 2013
762013
Exome-wide somatic mutation characterization of small bowel adenocarcinoma
UA Hänninen, R Katainen, T Tanskanen, RM Plaketti, R Laine, ...
PLoS genetics 14 (3), e1007200, 2018
752018
Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer
E Pitkänen, T Cajuso, R Katainen, E Kaasinen, N Välimäki, K Palin, ...
Oncotarget 5 (3), 853–859, 2014
662014
Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas
HR Heinonen, A Pasanen, O Heikinheimo, T Tanskanen, K Palin, ...
Scientific reports 7 (1), 1015, 2017
622017
Comparative analysis of molecular fingerprints in prediction of drug combination effects
B Zagidullin, Z Wang, Y Guan, E Pitkänen, J Tang
Briefings in bioinformatics 22 (6), bbab291, 2021
612021
Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
T Cajuso, P Sulo, T Tanskanen, R Katainen, A Taira, UA Hänninen, ...
Nature communications 10 (1), 4022, 2019
612019
Towards structured output prediction of enzyme function
K Astikainen, L Holm, E Pitkänen, S Szedmak, J Rousu
BMC proceedings 2 (Suppl 4), S2, 2008
602008
MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas
K Kämpjärvi, N Mäkinen, M Mehine, S Välipakka, O Uimari, E Pitkänen, ...
British journal of cancer 114 (12), 1405-1411, 2016
542016
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