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Simeng Lin
Simeng Lin
Exeter IBD Research Group
Verifierad e-postadress på exeter.ac.uk
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Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
6332019
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
NA Kennedy, S Lin, JR Goodhand, N Chanchlani, B Hamilton, ...
Gut 70 (10), 1884-1893, 2021
292*2021
Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab
NA Kennedy, JR Goodhand, C Bewshea, R Nice, D Chee, S Lin, ...
Gut 70 (5), 865-875, 2021
1852021
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab
S Lin, NA Kennedy, A Saifuddin, DM Sandoval, CJ Reynolds, RC Seoane, ...
Nature communications 13 (1), 1379, 2022
852022
Adalimumab and infliximab impair SARS-CoV-2 antibody responses: results from a therapeutic drug monitoring study in 11 422 biologic-treated patients
N Chanchlani, S Lin, D Chee, B Hamilton, R Nice, Z Arkir, C Bewshea, ...
Journal of Crohn's and Colitis 16 (3), 389-397, 2022
512022
Long-term outcomes in patients diagnosed with bile-acid diarrhoea
S Lin, DS Sanders, JT Gleeson, C Osborne, L Messham, M Kurien
European Journal of Gastroenterology & Hepatology 28 (2), 240-245, 2016
392016
Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic
NA Kennedy, M Janjua, N Chanchlani, S Lin, C Bewshea, R Nice, ...
Gut 72 (2), 295-305, 2023
372023
The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients
JL Alexander, BH Mullish, NP Danckert, Z Liu, ML Olbei, A Saifuddin, ...
EBioMedicine 88, 2023
362023
Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic
S Lin, LHS Lau, N Chanchlani, NA Kennedy, SC Ng
Gut 71 (7), 1426-1439, 2022
322022
Quality improvement project identifies factors associated with delay in IBD diagnosis
GJ Walker, S Lin, N Chanchlani, A Thomas, P Hendy, N Heerasing, ...
Alimentary Pharmacology & Therapeutics 52 (3), 471-480, 2020
292020
Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA. 1 and BA. 4/5 variants in patients with inflammatory bowel disease treated with infliximab and …
Z Liu, K Le, X Zhou, JL Alexander, S Lin, C Bewshea, N Chanchlani, ...
The Lancet Gastroenterology & Hepatology 8 (2), 145-156, 2023
272023
Root‐cause analyses of missed opportunities for the diagnosis of colorectal cancer in patients with inflammatory bowel disease
C Gordon, D Chee, B Hamilton, NM Heerasing, P Hendy, N Chanchlani, ...
Alimentary pharmacology & therapeutics 53 (2), 291-301, 2021
242021
Patient-led Remote IntraCapillary pharmacoKinetic Sampling (fingerPRICKS) for therapeutic drug monitoring in patients with inflammatory bowel disease
D Chee, R Nice, B Hamilton, E Jones, S Hawkins, C Redstone, V Cairnes, ...
Journal of Crohn's and Colitis 16 (2), 190-198, 2022
182022
UK Inflammatory Bowel Disease Pharmacogenetics Study Group Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn’s disease: a …
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
Lancet Gastroenterol Hepatol 4 (5), 341, 2019
182019
Covid-19 vaccine-induced antibodies are attenuated and decay rapidly in infliximab treated patients
S Lin, NA Kennedy, A Saifuddin, DM Sandoval, C Reynolds, RC Seoane, ...
152021
Implications for sequencing of biologic therapy and choice of second anti‐TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti‐TNF …
N Chanchlani, S Lin, MK Auth, CL Lee, H Robbins, S Looi, SV Murugesan, ...
Alimentary Pharmacology & Therapeutics 56 (8), 1250-1263, 2022
142022
Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study
GJ Walker, N Chanchlani, A Thomas, S Lin, L Moore, NM Heerasing, ...
Archives of Disease in Childhood 105 (10), 957-963, 2020
132020
Clinical features and genetic risk of demyelination following anti-TNF treatment
S Lin, HD Green, P Hendy, NM Heerasing, N Chanchlani, B Hamilton, ...
Journal of Crohn's and Colitis 14 (12), 1653-1661, 2020
112020
Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease
M Hanić, F Vučković, H Deriš, C Bewshea, S Lin, JR Goodhand, T Ahmad, ...
Biomolecules 13 (6), 954, 2023
82023
Whole blood DNA methylation changes are associated with anti-TNF drug concentration in patients with Crohn's disease
S Lin, E Hannon, M Reppell, JF Waring, N Smaoui, V Pivorunas, H Guay, ...
medRxiv, 2023.03. 22.23287574, 2023
82023
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Artiklar 1–20