Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ... The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019 | 633 | 2019 |
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD NA Kennedy, S Lin, JR Goodhand, N Chanchlani, B Hamilton, ... Gut 70 (10), 1884-1893, 2021 | 292* | 2021 |
Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab NA Kennedy, JR Goodhand, C Bewshea, R Nice, D Chee, S Lin, ... Gut 70 (5), 865-875, 2021 | 185 | 2021 |
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab S Lin, NA Kennedy, A Saifuddin, DM Sandoval, CJ Reynolds, RC Seoane, ... Nature communications 13 (1), 1379, 2022 | 85 | 2022 |
Adalimumab and infliximab impair SARS-CoV-2 antibody responses: results from a therapeutic drug monitoring study in 11 422 biologic-treated patients N Chanchlani, S Lin, D Chee, B Hamilton, R Nice, Z Arkir, C Bewshea, ... Journal of Crohn's and Colitis 16 (3), 389-397, 2022 | 51 | 2022 |
Long-term outcomes in patients diagnosed with bile-acid diarrhoea S Lin, DS Sanders, JT Gleeson, C Osborne, L Messham, M Kurien European Journal of Gastroenterology & Hepatology 28 (2), 240-245, 2016 | 39 | 2016 |
Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic NA Kennedy, M Janjua, N Chanchlani, S Lin, C Bewshea, R Nice, ... Gut 72 (2), 295-305, 2023 | 37 | 2023 |
The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients JL Alexander, BH Mullish, NP Danckert, Z Liu, ML Olbei, A Saifuddin, ... EBioMedicine 88, 2023 | 36 | 2023 |
Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic S Lin, LHS Lau, N Chanchlani, NA Kennedy, SC Ng Gut 71 (7), 1426-1439, 2022 | 32 | 2022 |
Quality improvement project identifies factors associated with delay in IBD diagnosis GJ Walker, S Lin, N Chanchlani, A Thomas, P Hendy, N Heerasing, ... Alimentary Pharmacology & Therapeutics 52 (3), 471-480, 2020 | 29 | 2020 |
Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA. 1 and BA. 4/5 variants in patients with inflammatory bowel disease treated with infliximab and … Z Liu, K Le, X Zhou, JL Alexander, S Lin, C Bewshea, N Chanchlani, ... The Lancet Gastroenterology & Hepatology 8 (2), 145-156, 2023 | 27 | 2023 |
Root‐cause analyses of missed opportunities for the diagnosis of colorectal cancer in patients with inflammatory bowel disease C Gordon, D Chee, B Hamilton, NM Heerasing, P Hendy, N Chanchlani, ... Alimentary pharmacology & therapeutics 53 (2), 291-301, 2021 | 24 | 2021 |
Patient-led Remote IntraCapillary pharmacoKinetic Sampling (fingerPRICKS) for therapeutic drug monitoring in patients with inflammatory bowel disease D Chee, R Nice, B Hamilton, E Jones, S Hawkins, C Redstone, V Cairnes, ... Journal of Crohn's and Colitis 16 (2), 190-198, 2022 | 18 | 2022 |
UK Inflammatory Bowel Disease Pharmacogenetics Study Group Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn’s disease: a … NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ... Lancet Gastroenterol Hepatol 4 (5), 341, 2019 | 18 | 2019 |
Covid-19 vaccine-induced antibodies are attenuated and decay rapidly in infliximab treated patients S Lin, NA Kennedy, A Saifuddin, DM Sandoval, C Reynolds, RC Seoane, ... | 15 | 2021 |
Implications for sequencing of biologic therapy and choice of second anti‐TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti‐TNF … N Chanchlani, S Lin, MK Auth, CL Lee, H Robbins, S Looi, SV Murugesan, ... Alimentary Pharmacology & Therapeutics 56 (8), 1250-1263, 2022 | 14 | 2022 |
Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study GJ Walker, N Chanchlani, A Thomas, S Lin, L Moore, NM Heerasing, ... Archives of Disease in Childhood 105 (10), 957-963, 2020 | 13 | 2020 |
Clinical features and genetic risk of demyelination following anti-TNF treatment S Lin, HD Green, P Hendy, NM Heerasing, N Chanchlani, B Hamilton, ... Journal of Crohn's and Colitis 14 (12), 1653-1661, 2020 | 11 | 2020 |
Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease M Hanić, F Vučković, H Deriš, C Bewshea, S Lin, JR Goodhand, T Ahmad, ... Biomolecules 13 (6), 954, 2023 | 8 | 2023 |
Whole blood DNA methylation changes are associated with anti-TNF drug concentration in patients with Crohn's disease S Lin, E Hannon, M Reppell, JF Waring, N Smaoui, V Pivorunas, H Guay, ... medRxiv, 2023.03. 22.23287574, 2023 | 8 | 2023 |