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Paul A Dickinson
Paul A Dickinson
Seda Pharmaceutical Development Services
Verifierad e-postadress på sedapds.com - Startsida
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AZD9291 in EGFR inhibitor–resistant non–small-cell lung cancer
PA Jänne, JCH Yang, DW Kim, D Planchard, Y Ohe, SS Ramalingam, ...
New England Journal of Medicine 372 (18), 1689-1699, 2015
22722015
In vitro models for the prediction of in vivo performance of oral dosage forms
ES Kostewicz, B Abrahamsson, M Brewster, J Brouwers, J Butler, ...
European Journal of Pharmaceutical Sciences 57, 342-366, 2014
3982014
The effects of pharmaceutical excipients on drug disposition
TR Buggins, PA Dickinson, G Taylor
Advanced drug delivery reviews 59 (15), 1482-1503, 2007
1702007
Clinical relevance of dissolution testing in quality by design
PA Dickinson, WW Lee, PW Stott, AI Townsend, JP Smart, P Ghahramani, ...
The AAPS journal 10, 380-390, 2008
1682008
Osimertinib Western and Asian clinical pharmacokinetics in patients and healthy volunteers: implications for formulation, dose, and dosing frequency in pivotal clinical studies
D Planchard, KH Brown, DW Kim, SW Kim, Y Ohe, E Felip, P Leese, ...
Cancer Chemotherapy and pharmacology 77, 767-776, 2016
1312016
An investigation into the utility of a multi-compartmental, dynamic, system of the upper gastrointestinal tract to support formulation development and establish bioequivalence …
PA Dickinson, R Abu Rmaileh, L Ashworth, RA Barker, WM Burke, ...
The AAPS journal 14 (2), 196-205, 2012
1222012
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation
AT Larsen, AG Ohlsson, B Polentarutti, RA Barker, AR Phillips, ...
European Journal of Pharmaceutical Sciences 48 (1-2), 339-350, 2013
1122013
Metabolic disposition of osimertinib in rats, dogs, and humans: insights into a drug designed to bind covalently to a cysteine residue of epidermal growth factor receptor
PA Dickinson, MV Cantarini, J Collier, P Frewer, S Martin, K Pickup, ...
Drug Metabolism and Disposition 44 (8), 1201-1212, 2016
1062016
The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance
A Selen, PA Dickinson, A Müllertz, JR Crison, HB Mistry, MT Cruañes, ...
Journal of Pharmaceutical Sciences 103 (11), 3377-3397, 2014
722014
An investigation of the disintegration of tablets in biorelevant media
S Anwar, JT Fell, PA Dickinson
International journal of pharmaceutics 290 (1-2), 121-127, 2005
672005
The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages
BG Jones, PA Dickinson, M Gumbleton, IW Kellaway
International journal of pharmaceutics 236 (1-2), 65-79, 2002
672002
Pharmacokinetics of gefitinib in humans: the influence of gastrointestinal factors
E Bergman, P Forsell, EM Persson, L Knutson, P Dickinson, R Smith, ...
International journal of pharmaceutics 341 (1-2), 134-142, 2007
652007
Novel nanoparticles for pulmonary drug administration
PA Dickinson, SW Howells, IW Kellaway
Journal of drug targeting 9 (4), 295-302, 2001
632001
Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans
HA Thörn, A Lundahl, JA Schrickx, PA Dickinson, H Lennernäs
European journal of pharmaceutical sciences 43 (3), 89-98, 2011
622011
AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - Results of two parallel first-in-human Phase I studies.
A Omlin, RJ Jones, R van der Noll, T Satoh, M Niwakawa, SA Smith, ...
Investigational New Drugs. 33 (3), 679-690., 2015
552015
The effect of itraconazole and rifampicin on the pharmacokinetics of osimertinib
K Vishwanathan, PA Dickinson, K So, K Thomas, YM Chen, ...
British journal of clinical pharmacology 84 (6), 1156-1169, 2018
512018
The effect of food or omeprazole on the pharmacokinetics of osimertinib in patients with non‐small‐cell lung cancer and in healthy volunteers
K Vishwanathan, PA Dickinson, K Bui, PA Cassier, A Greystoke, E Lisbon, ...
The Journal of Clinical Pharmacology 58 (4), 474-484, 2018
482018
Particulate composition
PA Dickinson, IW Kellaway, SW Howells
US Patent 7,018,657, 2006
482006
Lung surfactant phospholipids inhibit the uptake of respirable microspheres by the alveolar macrophage NR8383
BG Jones, PA Dickinson, M Gumbleton, IW Kellaway
Journal of pharmacy and pharmacology 54 (8), 1065-1072, 2002
452002
An investigation of the solubility of various compounds in the hydrofluoroalkane propellants and possible model liquid propellants
PA Dickinson, PC Seville, H McHale, NC Perkins, G Taylor
Journal of aerosol medicine 13 (3), 179-186, 2000
432000
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Artiklar 1–20