Gregor Blaha
Gregor Blaha
Assistant Professor of Biochemistry, UC Riverside
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Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance
D Tu, G Blaha, PB Moore, TA Steitz
Cell 121 (2), 257-270, 2005
Dissection of the mechanism for the stringent factor RelA
TM Wendrich, G Blaha, DN Wilson, MA Marahiel, KH Nierhaus
Molecular cell 10 (4), 779-788, 2002
Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome
G Blaha, RE Stanley, TA Steitz
science 325 (5943), 966-970, 2009
[19] Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy
G Blaha, U Stelzl, CMT Spahn, RK Agrawal, J Frank, KH Nierhaus
Academic Press 317, 292-309, 2000
Revisiting the structures of several antibiotics bound to the bacterial ribosome
D Bulkley, CA Innis, G Blaha, TA Steitz
Proceedings of the National Academy of Sciences 107 (40), 17158-17163, 2010
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
RE Stanley, G Blaha, RL Grodzicki, MD Strickler, TA Steitz
Nature structural & molecular biology 17 (3), 289, 2010
How hibernation factors RMF, HPF, and YfiA turn off protein synthesis
YS Polikanov, GM Blaha, TA Steitz
Science 336 (6083), 915-918, 2012
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:: The Structures of Tiamulin, Homoharringtonine, and Bruceantin Bound to the Ribosome
G Gürel, G Blaha, PB Moore, TA Steitz
Journal of molecular biology 389 (1), 146-156, 2009
Localization of the ribosomal protection protein Tet (O) on the ribosome and the mechanism of tetracycline resistance
CMT Spahn, G Blaha, RK Agrawal, P Penczek, RA Grassucci, CA Trieber, ...
Molecular cell 7 (5), 1037-1045, 2001
Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome
DN Wilson, G Blaha, SR Connell, PV Ivanov, H Jenke, U Stelzl, Y Teraoka, ...
Current Protein and Peptide Science 3 (1), 1-53, 2002
Mutations outside the anisomycin-binding site can make ribosomes drug-resistant
G Blaha, G Gürel, SJ Schroeder, PB Moore, TA Steitz
Journal of molecular biology 379 (3), 505-519, 2008
The structure of LepA, the ribosomal back translocase
RN Evans, G Blaha, S Bailey, TA Steitz
Proceedings of the National Academy of Sciences 105 (12), 4673-4678, 2008
Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui
G Gürel, G Blaha, TA Steitz, PB Moore
Antimicrobial agents and chemotherapy 53 (12), 5010-5014, 2009
Localization of the trigger factor binding site on the ribosomal 50 S subunit
G Blaha, DN Wilson, G Stoller, G Fischer, R Willumeit, KH Nierhaus
Journal of molecular biology 326 (3), 887-897, 2003
Insights into base selectivity from the 1.8 Å resolution structure of an RB69 DNA polymerase ternary complex
M Wang, S Xia, G Blaha, TA Steitz, WH Konigsberg, J Wang
Biochemistry 50 (4), 581-590, 2011
The structures of antibiotics bound to the E site region of the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole
SJ Schroeder, G Blaha, J Tirado-Rives, TA Steitz, PB Moore
Journal of molecular biology 367 (5), 1471-1479, 2007
Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit
SJ Schroeder, G Blaha, PB Moore
Antimicrobial agents and chemotherapy 51 (12), 4462-4465, 2007
The E3 Ubiquitin Ligase XIAP Restricts Anaplasma phagocytophilum Colonization of Ixodes scapularis Ticks
MS Severo, A Choy, KD Stephens, OS Sakhon, G Chen, DWD Chung, ...
The Journal of infectious diseases 208 (11), 1830-1840, 2013
Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit
MA Schäfer, AÖ Tastan, S Patzke, G Blaha, CMT Spahn, DN Wilson, ...
Journal of Biological Chemistry 277 (21), 19095-19105, 2002
Structural insights into complete metal ion coordination from ternary complexes of B family RB69 DNA polymerase
S Xia, M Wang, G Blaha, WH Konigsberg, J Wang
Biochemistry 50 (42), 9114-9124, 2011
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