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mirgani r or mirghani r
mirgani r or mirghani r
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The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes
M Christensen, K Andersson, P Dalén, RA Mirghani, GJ Muirhead, ...
Clinical Pharmacology & Therapeutics 73 (6), 517-528, 2003
2202003
4β-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians
U Diczfalusy, J Miura, HK Roh, RA Mirghani, J Sayi, H Larsson, KG Bodin, ...
Pharmacogenetics and genomics 18 (3), 201-208, 2008
1692008
Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer
H Green, P Söderkvist, P Rosenberg, RA Mirghani, P Rymark, ...
Basic & clinical pharmacology & toxicology 104 (2), 130-137, 2009
1652009
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population
RA Mirghani, J Sayi, E Aklillu, A Allqvist, M Jande, A Wennerholm, ...
Pharmacogenetics and genomics 16 (9), 637-645, 2006
932006
Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography
RA Mirghani, Ö Ericsson, J Cook, P Yu, LL Gustafsson
Journal of Chromatography B: Biomedical Sciences and Applications 754 (1), 57-64, 2001
622001
The roles of cytochrome P450 3A4 and lA2 in the 3‐hydroxylation of quinine in vivo
RA Mirghani, U Hellgren, PA Westerberg, O Ericsson, L Bertilsson, ...
Clinical Pharmacology & Therapeutics 66 (5), 454-460, 1999
531999
CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity
H Gréen, K Skoglund, F Rommel, RA Mirghani, K Lotfi
European journal of clinical pharmacology 66, 383-386, 2010
502010
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers
A Allqvist, J Miura, L Bertilsson, RA Mirghani
European journal of clinical pharmacology 63, 173-179, 2007
482007
Metabolism and elimination of quinine in healthy volunteers
RA Mirghani, U Hellgren, L Bertilsson, LL Gustafsson, Ö Ericsson
European journal of clinical pharmacology 59, 423-427, 2003
482003
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man
RA Mirghani, Ö Ericsson, G Tybring, LL Gustafsson, L Bertilsson
European journal of clinical pharmacology 59, 23-28, 2003
482003
Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria
II Abdelrahim, I Adam, G Elghazali, LL Gustafsson, MI Elbashir, ...
Journal of Clinical pharmacy and Therapeutics 32 (1), 15-19, 2007
452007
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway
RA Mirghani, Ü Yasar, T Zheng, JM Cook, LL Gustafsson, G Tybring, ...
Drug metabolism and disposition 30 (12), 1368-1371, 2002
412002
Frequency of rs731236 (Taql), rs2228570 (Fok1) of Vitamin-D Receptor (VDR) gene in Emirati healthy population
E Osman, F Al Anouti, A Haq, R Mirgani, H Al Safar
Meta gene 6, 49-52, 2015
322015
High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper
Å Jansson, LL Gustafsson, RA Mirghani
Journal of Chromatography B 795 (1), 151-156, 2003
322003
Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of α-and 4-hydroxy metabolites in healthy subjects
A Wennerholm, A Allqvist, JO Svensson, LL Gustafsson, RA Mirghani, ...
European journal of clinical pharmacology 61, 113-118, 2005
282005
Simultaneous quantification of alprazolam, 4-and α-hydroxyalprazolam in plasma samples using liquid chromatography mass spectrometry
A Allqvist, A Wennerholm, JO Svensson, RA Mirghani
Journal of Chromatography B 814 (1), 127-131, 2005
252005
Distribution of the major cytochrome P450 (CYP) 2C9 genetic variants in a Saudi population
RA Mirghani, G Chowdhary, G Elghazali
Basic & clinical pharmacology & toxicology 109 (2), 111-114, 2011
232011
Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat
H Xie, P Afsharian, Y Terelius, RA Mirghani, Ü Yasar, AL Hagbjörk, ...
Xenobiotica 35 (3), 239-251, 2005
192005
High-performance liquid chromatographic method for the determination of the major quinine metabolite, 3-hydroxyquinine, in plasma and urine
RA Mirghani, Ö Ericsson, LL Gustafsson
Journal of Chromatography B: Biomedical Sciences and Applications 708 (1-2 …, 1998
121998
Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women
RA Mirghani, I Elagib, G Elghazali, U Hellgren, LL Gustafsson
European journal of clinical pharmacology 66, 1229-1234, 2010
112010
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Artiklar 1–20