| RNA toxicity and foci formation in microsatellite expansion diseases N Zhang, T Ashizawa Current opinion in genetics & development 44, 17-29, 2017 | 95 | 2017 |
| Structures of the RNA polymerase-σ54 reveal new and conserved regulatory strategies Y Yang, VC Darbari, N Zhang, D Lu, R Glyde, YP Wang, JT Winkelman, ... Science 349 (6250), 882-885, 2015 | 79 | 2015 |
| Structures of RNA polymerase closed and intermediate complexes reveal mechanisms of DNA opening and transcription initiation R Glyde, F Ye, VC Darbari, N Zhang, M Buck, X Zhang Molecular cell 67 (1), 106-116. e4, 2017 | 53 | 2017 |
| Coupling AAA protein function to regulated gene expression N Joly, N Zhang, M Buck, X Zhang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 108-116, 2012 | 49 | 2012 |
| The bacterial enhancer-dependent RNA polymerase N Zhang, VC Darbari, R Glyde, X Zhang, M Buck Biochemical Journal 473 (21), 3741-3753, 2016 | 40 | 2016 |
| A perspective on the enhancer dependent bacterial RNA polymerase N Zhang, M Buck Biomolecules 5 (2), 1012-1019, 2015 | 40 | 2015 |
| The role of the conserved phenylalanine in the σ54-interacting GAFTGA motif of bacterial enhancer binding proteins N Zhang, N Joly, PC Burrows, M Jovanovic, SR Wigneshweraraj, M Buck Nucleic acids research 37 (18), 5981-5992, 2009 | 38 | 2009 |
| ATPase site architecture is required for self-assembly and remodeling activity of a hexameric AAA+ transcriptional activator N Joly, N Zhang, M Buck Molecular cell 47 (3), 484-490, 2012 | 31 | 2012 |
| Genome wide interactions of wild-type and activator bypass forms of σ54 J Schaefer, C Engl, N Zhang, E Lawton, M Buck Nucleic acids research 43 (15), 7280-7291, 2015 | 25 | 2015 |
| The NtrY–NtrX two‐component system is involved in controlling nitrate assimilation in Herbaspirillum seropedicae strain SmR1 P Bonato, LR Alves, JH Osaki, LU Rigo, FO Pedrosa, EM Souza, N Zhang, ... The FEBS Journal 283 (21), 3919-3930, 2016 | 23 | 2016 |
| Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies A Sharma, RN Leach, C Gell, N Zhang, PC Burrows, DA Shepherd, ... Nucleic Acids Research 42 (8), 5177-5190, 2014 | 23 | 2014 |
| A CRISPR-Cas13a based strategy that tracks and degrades toxic RNA in myotonic dystrophy type 1 N Zhang, B Bewick, G Xia, D Furling, T Ashizawa Frontiers in Genetics 11, 594576, 2020 | 17 | 2020 |
| A common feature from different subunits of a homomeric AAA+ protein contacts three spatially distinct transcription elements N Zhang, N Joly, M Buck Nucleic acids research 40 (18), 9139-9152, 2012 | 17 | 2012 |
| Intravenously administered novel liposomes, DCL64, deliver oligonucleotides to cerebellar purkinje cells AT Ashizawa, J Holt, K Faust, W Liu, A Tiwari, N Zhang, T Ashizawa The Cerebellum 18, 99-108, 2019 | 15 | 2019 |
| Polyglutamine Expansion in Huntingtin and Mechanism of DNA Damage Repair Defects in Huntington’s Disease S Pradhan, R Gao, K Bush, N Zhang, Y Wairkar, P Sarkar Frontiers in Cellular Neuroscience, 2022 | 13 | 2022 |
| DNAzyme cleavage of CAG repeat RNA in polyglutamine diseases N Zhang, B Bewick, J Schultz, A Tiwari, R Krencik, A Zhang, K Adachi, ... Neurotherapeutics 18 (3), 1710-1728, 2021 | 12 | 2021 |
| Subunit Dynamics and Nucleotide-Dependent Asymmetry of an AAA+ Transcription Complex N Zhang, Y Gordiyenko, N Joly, E Lawton, CV Robinson, M Buck Journal of molecular biology 426 (1), 71-83, 2014 | 12 | 2014 |
| Use, exposure and omics characterisation of potential hazard in nanomaterials NL Ma, N Zhang, WTL Yong, S Misbah, F Hashim, CF Soon, GP Lim, ... Materials Today Advances 17, 100341, 2023 | 11 | 2023 |
| A Key Hydrophobic Patch Identified in an AAA+ Protein Essential for Its In Trans Inhibitory Regulation N Zhang, T Simpson, E Lawton, P Uzdavinys, N Joly, P Burrows, M Buck Journal of molecular biology 425 (15), 2656-2669, 2013 | 11 | 2013 |
| Mutations in RNA polymerase bridge helix and switch regions affect active-site networks and transcript-assisted hydrolysis N Zhang, J Schäfer, A Sharma, L Rayner, X Zhang, R Tuma, P Stockley, ... Journal of Molecular Biology 427 (22), 3516-3526, 2015 | 10 | 2015 |
