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Alexandre Escargueil
Alexandre Escargueil
Sorbonne Université
Verified email at inserm.fr
Title
Cited by
Cited by
Year
Catalytic topoisomerase II inhibitors in cancer therapy
AK Larsen, AE Escargueil, A Skladanowski
Pharmacology & therapeutics 99 (2), 167-181, 2003
5272003
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
AK Larsen, AE Escargueil, A Skladanowski
Pharmacology & therapeutics 85 (3), 217-229, 2000
5162000
The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane
A Garrigues, AE Escargueil, S Orlowski
Proceedings of the National Academy of Sciences 99 (16), 10347-10352, 2002
2792002
Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
DG Soares, AE Escargueil, V Poindessous, A Sarasin, A de Gramont, ...
Proceedings of the National Academy of Sciences 104 (32), 13062-13067, 2007
1982007
PARPs and the DNA damage response
FG Sousa, R Matuo, DG Soares, AE Escargueil, JAP Henriques, ...
Carcinogenesis 33 (8), 1433-1440, 2012
1812012
Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
A Lorz, T Lorenzi, J Clairambault, A Escargueil, B Perthame
Bulletin of mathematical biology 77, 1-22, 2015
1362015
P-glycoprotein and ‘lipid rafts’: some ambiguous mutual relationships (floating on them, building them or meeting them by chance?)
S Orlowski, S Martin, A Escargueil
Cellular and Molecular Life Sciences CMLS 63, 1038-1059, 2006
1362006
Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation
RH Chisholm, T Lorenzi, A Lorz, AK Larsen, LN Almeida, A Escargueil, ...
Cancer research 75 (6), 930-939, 2015
1352015
What histone code for DNA repair?
AE Escargueil, DG Soares, M Salvador, AK Larsen, JAP Henriques
Mutation Research/Reviews in Mutation Research 658 (3), 259-270, 2008
1332008
Mitotic phosphorylation of DNA topoisomerase II α by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469
AE Escargueil, SY Plisov, O Filhol, C Cochet, AK Larsen
Journal of Biological Chemistry 275 (44), 34710-34718, 2000
992000
Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by …
P Mésange, V Poindessous, M Sabbah, AE Escargueil, A de Gramont, ...
Oncotarget 5 (13), 4709, 2014
862014
Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells
DG Soares, MS Machado, CJ Rocca, V Poindessous, D Ouaret, A Sarasin, ...
Molecular cancer therapeutics 10 (8), 1481-1489, 2011
862011
5‐Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line
R Matuo, FG Sousa, AE Escargueil, I Grivicich, D Garcia‐Santos, ...
Journal of Applied Toxicology 29 (4), 308-316, 2009
832009
Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries
FJ Iborra, AE Escargueil, KY Kwek, A Akoulitchev, PR Cook
Journal of cell science 117 (6), 899-906, 2004
802004
Saccharomyces cerevisiae as a model system to study the response to anticancer agents
R Matuo, FG Sousa, DG Soares, D Bonatto, J Saffi, AE Escargueil, ...
Cancer chemotherapy and pharmacology 70, 491-502, 2012
762012
From DNA damage to G~ 2 arrest: the many roles of topoisomerase II
AK Larsen, AE Escargueil, A Skladanowski
PROGRESS IN CELL CYCLE RESEARCH. 5, 295-300, 2003
722003
EGFR-and VEGF (R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies
V Poindessous, D Ouaret, K El Ouadrani, A Battistella, VF Mégalophonos, ...
Clinical Cancer Research 17 (20), 6522-6530, 2011
612011
DNA alkylation damage and autophagy induction
DL Bordin, M Lima, G Lenz, J Saffi, LB Meira, P Mesange, DG Soares, ...
Mutation Research/Reviews in Mutation Research 753 (2), 91-99, 2013
492013
Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status
A Petitprez, V Poindessous, D Ouaret, M Regairaz, G Bastian, E Guérin, ...
International journal of oncology 42 (5), 1644-1653, 2013
422013
DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP
R Matuo, FG Sousa, AE Escargueil, DG Soares, I Grivicich, J Saffi, ...
Biochemical pharmacology 79 (2), 147-153, 2010
412010
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