Följ
Fabián E. Sáenz
Fabián E. Sáenz
Centro de Investigación para la Salud en América Latina
Verifierad e-postadress på puce.edu.ec
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Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
2462013
The Transmembrane Isoform of Plasmodium falciparum MAEBL Is Essential for the Invasion of Anopheles Salivary Glands
FE Saenz, B Balu, J Smith, SR Mendonca, JH Adams
PloS one 3 (5), e2287, 2008
602008
Malaria epidemiology in low-endemicity areas of the northern coast of Ecuador: high prevalence of asymptomatic infections
FE Sáenz, A Arévalo-Cortés, G Valenzuela, AF Vallejo, A Castellanos, ...
Malaria journal 16, 1-10, 2017
512017
Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium
RM Cross, DL Flanigan, A Monastyrskyi, AN LaCrue, FE Sáenz, ...
Journal of Medicinal Chemistry 57 (21), 8860-8879, 2014
422014
4(1H)-Quinolones with Liver Stage Activity against Plasmodium berghei
AN LaCrue, FE Sáenz, RM Cross, KO Udenze, A Monastyrskyi, S Stein, ...
Antimicrobial agents and chemotherapy 57 (1), 417-424, 2013
422013
Novel 4-Aminoquinoline Analogs Highly Active against the Blood and Sexual Stages of Plasmodium In Vivo and In Vitro
FE Sáenz, T Mutka, K Udenze, AMJ Oduola, DE Kyle
Antimicrobial agents and chemotherapy 56 (9), 4685-4692, 2012
412012
Clonal population expansion in an outbreak of Plasmodium falciparum on the northwest coast of Ecuador
FE Sáenz, LC Morton, SA Okoth, G Valenzuela, CA Vera-Arias, ...
Malaria journal 14, 1-10, 2015
382015
4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-Ones Prevent the Transmission of Plasmodium falciparum to Anopheles freeborni
FE Sáenz, AN LaCrue, RM Cross, JR Maignan, KO Udenze, R Manetsch, ...
Antimicrobial agents and chemotherapy 57 (12), 6187-6195, 2013
272013
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy
CA Vera-Arias, A Holzschuh, CO Oduma, K Badu, M Abdul-Hakim, ...
Elife 11, e72083, 2022
262022
The relative role of climate variation and control interventions on malaria elimination efforts in El Oro, Ecuador: a modeling study
IK Fletcher, AM Stewart-Ibarra, R Sippy, G Carrasco-Escobar, M Silva, ...
Frontiers in Environmental Science 8, 135, 2020
202020
Diverse origin of Plasmodium falciparum in northwest Ecuador
CA Vera-Arias, LE Castro, J Gómez-Obando, FE Sáenz
Malaria journal 18, 1-11, 2019
192019
Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med 5: 177ra37
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
192013
Anopheline and human drivers of malaria risk in northern coastal, Ecuador: a pilot study
JA Martin, AL Hendershot, IA Saá Portilla, DJ English, M Woodruff, ...
Malaria Journal 19, 1-11, 2020
182020
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model
PP Henrich, C O'Brien, FE Sáenz, S Cremers, DE Kyle, DA Fidock
Antimicrobial agents and chemotherapy 58 (1), 183-195, 2014
172014
Targeted disruption of maebl in Plasmodium falciparum
J Fu, FE Sáenz, MB Reed, B Balu, N Singh, PL Blair, AF Cowman, ...
Molecular and biochemical parasitology 141 (1), 113, 2005
162005
Lamina-associated polypeptide 2 (LAP2) expression in fish and amphibians.
EM Del-Pino, FE Saenz, OD Perez, FD Brown, ME Avila, VA Barragan, ...
International Journal of Developmental Biology 46 (2), 227-234, 2002
132002
Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis
M Carrasquilla, AM Early, AR Taylor, A Knudson Ospina, DF Echeverry, ...
PLoS pathogens 18 (12), e1010993, 2022
112022
Clinical malaria incidence following an outbreak in Ecuador was predominantly associated with Plasmodium falciparum with recombinant variant antigen gene …
S Ruybal-Pesántez, FE Sáenz, S Deed, EK Johnson, DB Larremore, ...
MedRxiv, 2021.04. 12.21255093, 2021
102021
Genotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
G Valenzuela, LE Castro, J Valencia-Zamora, CA Vera-Arias, P Rohrbach, ...
Malaria Journal 18, 1-13, 2019
102019
Molecular epidemiology of continued Plasmodium falciparum disease transmission after an outbreak in Ecuador
S Ruybal-Pesántez, FE Sáenz, SL Deed, EK Johnson, DB Larremore, ...
Frontiers in Tropical Diseases 4, 1085862, 2023
52023
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Artiklar 1–20