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Richard Bryan Tunnicliffe
Richard Bryan Tunnicliffe
Post doc
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Pressure‐induced changes in the solution structure of the GB1 domain of protein G
DJ Wilton, RB Tunnicliffe, YO Kamatari, K Akasaka, MP Williamson
Proteins: Structure, Function, and Bioinformatics 71 (3), 1432-1440, 2008
642008
Characterization of a double dockerin from the cellulosome of the anaerobic fungus Piromyces equi
T Nagy, RB Tunnicliffe, LD Higgins, C Walters, HJ Gilbert, MP Williamson
Journal of molecular biology 373 (3), 612-622, 2007
572007
Structure of a mannan-specific family 35 carbohydrate-binding module: evidence for significant conformational changes upon ligand binding
RB Tunnicliffe, DN Bolam, G Pell, HJ Gilbert, MP Williamson
Journal of molecular biology 347 (2), 287-296, 2005
562005
Structural basis for the recognition of cellular mRNA export factor REF by herpes viral proteins HSV-1 ICP27 and HVS ORF57
RB Tunnicliffe, GM Hautbergue, P Kalra, BR Jackson, A Whitehouse, ...
PLoS pathogens 7 (1), e1001244, 2011
522011
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding
H Troilo, AV Zuk, RB Tunnicliffe, AP Wohl, R Berry, RF Collins, TA Jowitt, ...
Proceedings of the National Academy of Sciences 111 (36), 13063-13068, 2014
472014
The solution structure of the PufX polypeptide from Rhodobacter sphaeroides
RB Tunnicliffe, EC Ratcliffe, CN Hunter, MP Williamson
FEBS letters 580 (30), 6967-6971, 2006
462006
Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module
MAS Correia, DW Abbott, TM Gloster, VO Fernandes, JAM Prates, ...
Biochemistry 49 (29), 6193-6205, 2010
412010
Experimental evidence that the membrane-spanning helix of PufX adopts a bent conformation that facilitates dimerisation of the Rhodobacter sphaeroides RC–LH1 complex through N …
EC Ratcliffe, RB Tunnicliffe, IW Ng, PG Adams, P Qian, K Holden-Dye, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (1), 95-107, 2011
372011
Novel xylan-binding properties of an engineered family 4 carbohydrate-binding module
L Cicortas Gunnarsson, C Montanier, RB Tunnicliffe, MP Williamson, ...
Biochemical Journal 406 (2), 209-214, 2007
362007
An experimental investigation of conformational fluctuations in proteins G and L
RB Tunnicliffe, JL Waby, RJ Williams, MP Williamson
Structure 13 (11), 1677-1684, 2005
352005
The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer
RB Tunnicliffe, M Schacht, C Levy, TA Jowitt, RM Sandri-Goldin, ...
Scientific reports 5 (1), 11234, 2015
272015
The herpes viral transcription factor ICP4 forms a novel DNA recognition complex
RB Tunnicliffe, MP Lockhart-Cairns, C Levy, AP Mould, TA Jowitt, H Sito, ...
Nucleic acids research 45 (13), 8064-8078, 2017
252017
Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF
RB Tunnicliffe, GM Hautbergue, SA Wilson, P Kalra, AP Golovanov
PLoS pathogens 10 (2), e1003907, 2014
252014
Molecular mechanism of SR protein kinase 1 inhibition by the herpes virus protein ICP27
RB Tunnicliffe, WK Hu, MY Wu, C Levy, AP Mould, EA McKenzie, ...
MBio 10 (5), 10.1128/mbio. 02551-19, 2019
222019
Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway
H Troilo, AL Barrett, AV Zuk, MP Lockhart-Cairns, AP Wohl, CP Bayley, ...
Matrix Biology 55, 49-62, 2016
172016
Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF
RB Tunnicliffe, X Tian, J Storer, RM Sandri-Goldin, AP Golovanov
Scientific Reports 8, 15005, 2018
152018
The ICP27 homology domain of the human cytomegalovirus protein UL69 adopts a dimer-of-dimers structure
RB Tunnicliffe, RF Collins, HD Ruiz Nivia, RM Sandri-Goldin, ...
MBio 9 (3), 10.1128/mbio. 01112-18, 2018
132018
Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition
RB Tunnicliffe, C Levy, HD Ruiz Nivia, RM Sandri-Goldin, AP Golovanov
Nucleic acids research 47 (4), 1987-2001, 2019
52019
A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening …
M Frederickson, IR Selvam, D Evangelopoulos, KJ McLean, MM Katariya, ...
European Journal of Medicinal Chemistry 230, 114105, 2022
42022
Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold
M Zalar, S Indrakumar, CW Levy, RB Tunnicliffe, GHJ Peters, ...
Scientific Reports 9 (1), 9067, 2019
42019
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