Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 565 | 2020 |
An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function L Wang, K Pang, K Han, CJ Adamski, W Wang, L He, JK Lai, VV Bondar, ... Molecular psychiatry 25 (10), 2534-2555, 2020 | 70 | 2020 |
A phylogenetic analysis of normal modes evolution in enzymes and its relationship to enzyme function J Lai, J Jin, J Kubelka, D Liberles Biophysical Journal 102 (3), 450a, 2012 | 27 | 2012 |
Sequence, structure, and cooperativity in folding of elementary protein structural motifs JK Lai, GS Kubelka, J Kubelka Proceedings of the National Academy of Sciences 112 (32), 9890-9895, 2015 | 25 | 2015 |
Enhancing structure prediction and design of soluble and membrane proteins with explicit solvent-protein interactions JK Lai, J Ambia, Y Wang, P Barth Structure 25 (11), 1758-1770. e8, 2017 | 23 | 2017 |
A new parameter‐rich structure‐aware mechanistic model for amino acid substitution during evolution PB Chi, D Kim, JK Lai, N Bykova, CC Weber, J Kubelka, DA Liberles Proteins: Structure, Function, and Bioinformatics 86 (2), 218-228, 2018 | 12 | 2018 |
The phylogenetic distribution and evolution of enzymes within the thymidine kinase 2-like gene family in metazoa A Konrad, J Lai, Z Mutahir, J Piškur, DA Liberles Journal of molecular evolution 78, 202-216, 2014 | 6 | 2014 |
Effect of mutations on the global and site-specific stability and folding of an elementary protein structural motif JK Lai, GS Kubelka, J Kubelka The Journal of Physical Chemistry B 122 (49), 11083-11094, 2018 | 4 | 2018 |
Computational design of highly signaling active membrane receptors through de novo solvent-mediated allosteric networks KY Chen, JK Lai, J Wang, AM Russell, K Conners, ME Rutter, B Condon, ... bioRxiv, 2021.09. 29.462228, 2021 | | 2021 |
Sequence, structure, and cooperativity in folding of elementary protein structural motifs (vol 112, pg 9890, 2015) JK Lai, GS Kubelka, J Kubelka PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2016 | | 2016 |
Statistical Mechanical Models for Analyzing the Site-Specific Folding of helix-turn-helix Motifs JK Lai, J Kubelka Biophysical Journal 106 (2), 671a-672a, 2014 | | 2014 |