Heterogeneous blood–tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer PR Lockman, RK Mittapalli, KS Taskar, V Rudraraju, B Gril, KA Bohn, ... Clinical cancer research 16 (23), 5664-5678, 2010 | 677 | 2010 |
Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer FC Thomas, K Taskar, V Rudraraju, S Goda, HR Thorsheim, JA Gaasch, ... Pharmaceutical research 26, 2486-2494, 2009 | 262 | 2009 |
Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cells JA Gaasch, PR Lockman, WJ Geldenhuys, DD Allen, CJ Van der Schyf Neurochemical research 32, 1196-1208, 2007 | 250 | 2007 |
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer KS Taskar, V Rudraraju, RK Mittapalli, R Samala, HR Thorsheim, ... Pharmaceutical research 29, 770-781, 2012 | 228 | 2012 |
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks D Palmieri, PR Lockman, FC Thomas, E Hua, J Herring, E Hargrave, ... Clinical Cancer Research 15 (19), 6148-6157, 2009 | 176 | 2009 |
Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures JA Gaasch, WJ Geldenhuys, PR Lockman, DD Allen, CJ Van der Schyf Neurochemical research 32, 1686-1693, 2007 | 74 | 2007 |
P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model CE Adkins, RK Mittapalli, VK Manda, MI Nounou, AS Mohammad, ... Frontiers in pharmacology 4, 136, 2013 | 63 | 2013 |
Quantitative fluorescence microscopy measures vascular pore size in primary and metastatic brain tumors RK Mittapalli, CE Adkins, KA Bohn, AS Mohammad, JA Lockman, ... Cancer research 77 (2), 238-246, 2017 | 60 | 2017 |
Differential effect of nimodipine in attenuating iron-induced toxicity in brain-and blood–brain barrier-associated cell types JA Lockman, WJ Geldenhuys, KA Bohn, SF Desilva, DD Allen, ... Neurochemical research 37, 134-142, 2012 | 26 | 2012 |
Using WebCt to implement a basic science competency education course PR Lockman, JA Gaasch, K Borges, A Ehlo, QR Smith American Journal of Pharmaceutical Education 72 (2), 2008 | 18 | 2008 |
NGP1-01, a multi-targeted polycyclic cage amine, attenuates brain endothelial cell death in iron overload conditions JA Lockman, WJ Geldenhuys, MR Jones-Higgins, JD Patrick, DD Allen, ... Brain research 1489, 133-139, 2012 | 17 | 2012 |
Hepatocyte growth factor-regulated genes in differentiated RAW 264.7 osteoclast and undifferentiated cells JA Gaasch, AB Bolwahnn, JS Lindsey Gene 369, 142-152, 2006 | 16 | 2006 |
Nicotine exposure does not alter plasma to brain choline transfer PR Lockman, J Gaasch, G McAfee, TJ Abbruscato, CJ Van der Schyf, ... Neurochemical research 31, 503-508, 2006 | 7 | 2006 |
ET-09: A new drug, ANG1005, a conjugate of Paclitaxel and Angiopep peptide vector able to cross the Blood-Brain Barrier for the treatment of brain cancers. R Gabathuler, M Demeule, A Régina, C Ché, P Lockman, F Thomas, ... | 3 | 2008 |
ANG1005, a new therapeutic drug able to cross the blood-brain barrier for the treatment of brain cancers. M Demeule, R Gabathuler, A Regina, C Che, P Lockman, F Thomas, ... Cancer Research 68 (9_Supplement), LB-108-LB-108, 2008 | 1 | 2008 |
Blood-tumor barrier permeability and drug uptake in an experimental model of brain metastases of breast cancer Q Smith, V Rudraraju, K Taskar, R Mittapalli, K Bohn, J Gaasch, ... Cancer Research 68 (9_Supplement), 1620-1620, 2008 | | 2008 |
Iron-overload toxicity in central nervous system-associated cells and its attenuation by calcium channel blockers JA Gaasch | | 2006 |