| Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay DM Molina, R Jafari, M Ignatushchenko, T Seki, EA Larsson, C Dan, ... Science 341 (6141), 84-87, 2013 | 1699 | 2013 |
| The cellular thermal shift assay for evaluating drug target interactions in cells R Jafari, H Almqvist, H Axelsson, M Ignatushchenko, T Lundbäck, ... Nature protocols 9 (9), 2100-2122, 2014 | 1077 | 2014 |
| Tracking cancer drugs in living cells by thermal profiling of the proteome MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ... Science 346 (6205), 1255784, 2014 | 983 | 2014 |
| Functional mapping and single chain construction of the anti-cytokeratin 8 monoclonal antibody TS1 P Holm, R Jafari, BE Sundström Molecular Immunology 44 (6), 1075-1084, 2007 | 322 | 2007 |
| CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil H Almqvist, H Axelsson, R Jafari, C Dan, A Mateus, M Haraldsson, ... Nature communications 7 (1), 11040, 2016 | 154 | 2016 |
| Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 140 | 2016 |
| Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia M Yang, M Vesterlund, I Siavelis, LH Moura-Castro, A Castor, T Fioretos, ... Nature communications 10 (1), 1519, 2019 | 72 | 2019 |
| Optimization of production of the anti-keratin 8 single-chain Fv TS1-218 in Pichia pastoris using design of experiments R Jafari, BE Sundström, P Holm Microbial cell factories 10, 1-8, 2011 | 41 | 2011 |
| Novel broad-spectrum antiviral inhibitors targeting host factors essential for replication of pathogenic RNA viruses M Tampere, A Pettke, C Salata, O Wallner, T Koolmeister, ... Viruses 12 (12), 1423, 2020 | 26 | 2020 |
| Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines IR Leo, L Aswad, M Stahl, E Kunold, F Post, T Erkers, N Struyf, ... Nature Communications 13 (1), 1691, 2022 | 25 | 2022 |
| Proteogenomics refines the molecular classification of chronic lymphocytic leukemia SA Herbst, M Vesterlund, AJ Helmboldt, R Jafari, I Siavelis, M Stahl, ... Nature Communications 13 (1), 6226, 2022 | 23 | 2022 |
| Construction of divalent anti-keratin 8 single-chain antibodies (sc (Fv) 2), expression in Pichia pastoris and their reactivity with multicellular tumor spheroids R Jafari, P Holm, M Piercecchi, BE Sundström Journal of immunological methods 364 (1-2), 65-76, 2011 | 18 | 2011 |
| Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy LC Cheung, C Aya-Bonilla, MN Cruickshank, SK Chiu, V Kuek, ... Leukemia 37 (1), 61-71, 2023 | 15 | 2023 |
| Deep thermal profiling for detection of functional proteoform groups N Kurzawa, IR Leo, M Stahl, E Kunold, I Becher, A Audrey, G Mermelekas, ... Nature Chemical Biology 19 (8), 962-971, 2023 | 13 | 2023 |
| Thermal proteome profiling identifies PIP4K2A and ZADH2 as off‐targets of Polo‐like kinase 1 inhibitor volasertib O Goroshchuk, I Kolosenko, E Kunold, L Vidarsdottir, M Pirmoradian, ... The FASEB Journal 35 (7), e21741, 2021 | 10 | 2021 |
| The transcriptome‐wide landscape of molecular subtype‐specific mRNA expression profiles in acute myeloid leukemia T Mou, Y Pawitan, M Stahl, M Vesterlund, W Deng, R Jafari, A Bohlin, ... American Journal of hematology 96 (5), 580-588, 2021 | 8 | 2021 |
| Localization of complexed anticytokeratin 8 scFv TS1-218 to HeLa HEp-2 multicellular tumor spheroids and experimental tumors R Jafari, P Holm, J Sandegren, T Stigbrand, BE Sundström Cancer biotherapy & radiopharmaceuticals 25 (4), 455-463, 2010 | 5 | 2010 |
| Deep thermal proteome profiling for detection of proteoforms and drug sensitivity biomarkers N Kurzawa, M Stahl, I Leo, E Kunold, I Becher, A Audrey, G Mermelekas, ... bioRxiv, 2022.06. 10.495491, 2022 | 2 | 2022 |
| Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound TA Giovannucci, FA Salomons, M Haraldsson, LHM Elfman, M Wickström, ... Cell Death & Disease 12 (10), 914, 2021 | 2 | 2021 |
| Prediction model for drug response of acute myeloid leukemia patients QT Trac, Y Pawitan, T Mou, T Erkers, P Östling, A Bohlin, A Österroos, ... NPJ Precision Oncology 7 (1), 32, 2023 | 1 | 2023 |
