Designing a polyvalent inhibitor of anthrax toxin M Mourez, RS Kane, J Mogridge, S Metallo, P Deschatelets, BR Sellman, ... Nature biotechnology 19 (10), 958-961, 2001 | 377 | 2001 |
Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax BR Sellman, M Mourez, RJ Collier Science 292 (5517), 695-697, 2001 | 251 | 2001 |
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa A DiGiandomenico, AE Keller, C Gao, GJ Rainey, P Warrener, ... Science Translational Medicine 6 (262), 262ra155-262ra155, 2014 | 186 | 2014 |
Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia L Hua, JJ Hilliard, Y Shi, C Tkaczyk, LI Cheng, X Yu, V Datta, S Ren, ... Antimicrobial agents and chemotherapy 58 (2), 1108-1117, 2014 | 131 | 2014 |
Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease A Jenkins, BA Diep, TT Mai, NH Vo, P Warrener, J Suzich, CK Stover, ... MBio 6 (1), 2015 | 119 | 2015 |
Point mutations in anthrax protective antigen that block translocation BR Sellman, S Nassi, RJ Collier Journal of biological chemistry 276 (11), 8371-8376, 2001 | 117 | 2001 |
Identification of anti-alpha toxin monoclonal antibodies that reduce the severity of Staphylococcus aureus dermonecrosis and exhibit a correlation between affinity and potency C Tkaczyk, L Hua, R Varkey, Y Shi, L Dettinger, R Woods, A Barnes, ... Clinical and Vaccine Immunology 19 (3), 377-385, 2012 | 115 | 2012 |
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models P Warrener, R Varkey, JC Bonnell, A DiGiandomenico, M Camara, ... Antimicrobial agents and chemotherapy 58 (8), 4384-4391, 2014 | 93 | 2014 |
Moving toward endotypes in atopic dermatitis: identification of patient clusters based on serum biomarker analysis JL Thijs, I Strickland, CAFM Bruijnzeel-Koomen, S Nierkens, ... Journal of Allergy and Clinical Immunology 140 (3), 730-737, 2017 | 87 | 2017 |
Generation of a membrane‐bound, oligomerized pre‐pore complex is necessary for pore formation by Clostridium septicum alpha toxin BR Sellman, BL Kagan, RK Tweten Molecular microbiology 23 (3), 551-558, 1997 | 81 | 1997 |
Identification of immunogenic and serum binding proteins of Staphylococcus epidermidis BR Sellman, AP Howell, C Kelly-Boyd, SM Baker Infection and immunity 73 (10), 6591-6600, 2005 | 76 | 2005 |
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections TS Cohen, JJ Hilliard, O Jones-Nelson, AE Keller, T O’Day, C Tkaczyk, ... Science Translational Medicine 8 (329), 329ra31-329ra31, 2016 | 73 | 2016 |
Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model C Tkaczyk, MM Hamilton, V Datta, XP Yang, JJ Hilliard, GL Stephens, ... PLoS One 8 (10), e75103, 2013 | 73 | 2013 |
2001: a year of major advances in anthrax toxin research M Mourez, DB Lacy, K Cunningham, R Legmann, BR Sellman, ... TRENDS in Microbiology 10 (6), 287-293, 2002 | 72 | 2002 |
Antibacterial monoclonal antibodies: the next generation? A DiGiandomenico, BR Sellman Current opinion in microbiology 27, 78-85, 2015 | 69 | 2015 |
Mechanisms of neutralization of a human anti-α-toxin antibody V Oganesyan, L Peng, MM Damschroder, L Cheng, A Sadowska, ... Journal of Biological Chemistry 289 (43), 29874-29880, 2014 | 68 | 2014 |
Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus … BA Diep, A Afasizheva, HN Le, O Kajikawa, G Matute-Bello, C Tkaczyk, ... The Journal of infectious diseases 208 (1), 75-82, 2013 | 68 | 2013 |
α-Toxin induces platelet aggregation and liver injury during Staphylococcus aureus sepsis BGJ Surewaard, A Thanabalasuriar, Z Zeng, C Tkaczyk, TS Cohen, ... Cell host & microbe 24 (2), 271-284. e3, 2018 | 57 | 2018 |
IVIG-mediated protection against necrotizing pneumonia caused by MRSA BA Diep, VTM Le, C Badiou, HN Le, MG Pinheiro, AH Duong, X Wang, ... Science translational medicine 8 (357), 357ra124-357ra124, 2016 | 57 | 2016 |
Heterogeneous in vivo expression of clumping factor A and capsular polysaccharide by Staphylococcus aureus: implications for vaccine design JS Nanra, Y Timofeyeva, SM Buitrago, BR Sellman, DA Dilts, P Fink, ... Vaccine 27 (25-26), 3276-3280, 2009 | 57 | 2009 |