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Javier Oroz
Javier Oroz
Rocasolano Institute for Physical Chemistry
Verifierad e-postadress på iqfr.csic.es
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On the remarkable mechanostability of scaffoldins and the mechanical clamp motif
A Valbuena, J Oroz, R Hervás, AM Vera, D Rodríguez, M Menéndez, ...
Proceedings of the National Academy of Sciences 106 (33), 13791-13796, 2009
1412009
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
SA Mok, C Condello, R Freilich, A Gillies, T Arhar, J Oroz, H Kadavath, ...
Nature structural & molecular biology 25 (5), 384-393, 2018
1312018
ASC pyrin domain self-associates and binds NLRP3 protein using equivalent binding interfaces
J Oroz, S Barrera-Vilarmau, C Alfonso, G Rivas, E De Alba
Journal of Biological Chemistry 291 (37), 19487-19501, 2016
842016
Common features at the start of the neurodegeneration cascade
R Hervas, J Oroz, A Galera-Prat, O Goni, A Valbuena, AM Vera, ...
PLoS biology 10 (5), e1001335, 2012
762012
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex
J Oroz, BJ Chang, P Wysoczanski, CT Lee, Á Pérez-Lara, P Chakraborty, ...
Nature communications 9 (1), 4532, 2018
742018
Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90
J Oroz, JH Kim, BJ Chang, M Zweckstetter
Nature structural & molecular biology 24 (4), 407-413, 2017
552017
Nanomechanics of the cadherin ectodomain:“canalization” by Ca2+ binding results in a new mechanical element
J Oroz, A Valbuena, AM Vera, J Mendieta, P Gómez-Puertas, ...
Journal of Biological Chemistry 286 (11), 9405-9418, 2011
542011
Global structure of the intrinsically disordered protein tau emerges from its local structure
LS Stelzl, LM Pietrek, A Holla, J Oroz, M Sikora, J Köfinger, B Schuler, ...
Jacs Au 2 (3), 673-686, 2022
522022
Mechanical properties of β-catenin revealed by single-molecule experiments
A Valbuena, AM Vera, J Oroz, M Menéndez, M Carrión-Vázquez
Biophysical journal 103 (8), 1744-1752, 2012
392012
Protein nanomechanics—as studied by AFM single-molecule force spectroscopy
M Carrión-Vázquez, AF Oberhauser, H Diez, R Hervás, J Oroz, ...
Advanced Techniques in Biophysics, 163-245, 2006
362006
Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau
P Gracia, D Polanco, J Tarancón-Díez, I Serra, M Bracci, J Oroz, ...
Nature Communications 13 (1), 4586, 2022
262022
Mechanistic insights into the role of molecular chaperones in protein misfolding diseases: from molecular recognition to amyloid disassembly
R Hervás, J Oroz
International journal of molecular sciences 21 (23), 9186, 2020
252020
Unequivocal single-molecule force spectroscopy of proteins by AFM using pFS vectors
J Oroz, R Hervas, M Carrion-Vazquez
Biophysical journal 102 (3), 682-690, 2012
252012
Quasi-simultaneous imaging/pulling analysis of single polyprotein molecules by atomic force microscopy
A Valbuena, J Oroz, AM Vera, A Gimeno, J Gomez-Herrero, ...
Review of Scientific Instruments 78 (11), 2007
232007
Dynamic Aha1 co‐chaperone binding to human Hsp90
J Oroz, LJ Blair, M Zweckstetter
Protein Science 28 (9), 1545-1551, 2019
222019
Structure of monomeric transthyretin carrying the clinically important T119M mutation
JH Kim, J Oroz, M Zweckstetter
Angewandte Chemie International Edition 55 (52), 16168-16171, 2016
212016
Molecular basis of the interaction of Hsp90 with its co‐chaperone Hop
A Lott, J Oroz, M Zweckstetter
Protein Science 29 (12), 2422-2432, 2020
182020
Nanomechanics of tip-link cadherins
J Oroz, A Galera-Prat, R Hervás, A Valbuena, D Fernández-Bravo, ...
Scientific Reports 9 (1), 13306, 2019
182019
The Y9P variant of the titin I27 module: Structural determinants of its revisited nanomechanics
J Oroz, M Bruix, DV Laurents, A Galera-Prat, J Schönfelder, ...
Structure 24 (4), 606-616, 2016
152016
Do polyproline II helix associations modulate biomolecular condensates?
M Mompeán, J Oroz, DV Laurents
FEBS Open bio 11 (9), 2390-2399, 2021
142021
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Artiklar 1–20